Antithrombogenic platiniferous ceramic composition and article containing the same

Abstract

An antithrombotic composition comprising (i) alumina, (ii) at least one substance selected from silica and titanium oxide, and (iii) at least one element or compound selected from platinum or a platinum compound, palladium or a palladium compound, iridium or an iridium compound and rhodium or a rhodium compound, and an article such as clothing, bedding and so forth comprising the composition. The antithrombotic property can be worked by the composition or the article without lapsing into bleeding tendency.

1 . An antithrombotic composition comprising (i)alumina, (ii) at least one substance selected from silica and titanium oxide, and (iii) at least one element or compound selected from platinum or a platinum compound, palladium or a palladium compound, iridium or an iridium compound and rhodium or a rhodium compound.  
     
     
         2 . A composition according to  claim 1  additionally comprising (iv) at least one element or compound selected from silver or a silver compound and gold or a gold compound.  
     
     
         3 . An antithrombotic article comprising a composition according to  claim 1  or  2 .  
     
     
         4 . Antithrombotic clothing comprising a composition according to  claim 1  or  2 .  
     
     
         5 . Antithrombotic bedding comprising a composition according to  claim 1  or  2 .  
     
     
         6 . (canceled)  
     
     
         7 . (canceled)  
     
     
         8 . A method of preparing the antithrombotic composition of  claim 1  or  2 , comprising: 
 step (a) mixing alumina particles with platinum or platinum oxide dispersed in a colloid, and  
 step (b-1) preparing silica particles and/or titanium oxide particles, or  
 step (b-2) mixing silica particles and/or titanium oxide particles with platinum or platinum oxide dispersed in a colloid, and  
 step (c) mixing the particles resulted from step (a) and step (b-1) or (b-2), and if necessary, further comprising  
 step (d) adding and mixing a powder of silver, gold or compound thereof.  
 
     
     
         9 . A method for preparing an antithrombotic article containing the antithrombotic composition of  claim 1  or  2  comprising: 
 step (i) blending the antithrombotic composition of  claim 1  or  2  into a synthetic polymer material of the fiber material which is then spun into filaments or hollow fibers and so forth to obtain a thread,  
 step (ii) blending threads obtained in step (i) with other threads not containing the composition of  claim 1  or  2 , such as cotton, hemp, silk, wool and other natural fibers or synthetic fibers, or  
 step (iii) mixing the antithrombotic composition or  claim 1  or  2  into a synthetic resin material and producing molded products of any desired shape.