Use of vitamin B6 to mitigate visual field defects associated with the use of GABAergic drugs in mammals

Abstract

The invention provides a method for treating visual field defects in a mammal in need thereof by administering an effective amount of vitamin B6 to the mammal. Novel compositions containing a GABAergic drug and vitamin B6 are also provided.

1 . A method for treating visual field defects in a mammal in need thereof comprising administering an effective amount of vitamin B6 to the mammal.  
     
     
         2 . The method according to  claim 1 , wherein the mammal is a human.  
     
     
         3 . The method according to  claim 1 , wherein the effective amount of vitamin B6 is from about 5 mg/day to about 300 mg/day.  
     
     
         4 . The method according to  claim 1 , wherein the effective amount of vitamin B6 is from about 50 mg/day to about 100 mg/day.  
     
     
         5 . The method according to  claim 1 , wherein the effective amount of vitamin B6 is from about 10 mg/day to about 50 mg/day.  
     
     
         6 . The method according to  claim 1 , wherein the mammal is being treated with gamma vinyl GABA for a drug addiction.  
     
     
         7 . The method according to  claim 1 , wherein the mammal is being treated with gamma vinyl GABA for a seizure disorder.  
     
     
         8 . The method according to  claim 1 , wherein the vitamin B6 is administered before, simultaneously of after administration of a GABAergic drug.  
     
     
         9 . A composition consisting essentially of a GABAergic drug and vitamin B6.  
     
     
         10 . The composition according to  claim 9 , wherein the GABAergic drug is gamma vinyl GABA.  
     
     
         11 . The composition according to  claim 9 , wherein the vitamin B6 is in an amount of about 5 mg/day to about 300 mg/day.  
     
     
         12 . The method according to  claim 9 , wherein the vitamin B6 is in an amount of about 50 mg/day to about 100 mg/day.  
     
     
         13 . The method according to  claim 9 , wherein the vitamin B6 is in an amount of about 10 mg/day to about 50 mg/day.  
     
     
         14 . The composition according to  claim 9 , wherein the gamma vinyl GABA is in an amount of about 100 mg/kg to about 300 mg/kg.  
     
     
         15 . The composition according to  claim 9 , wherein the GABAergic drug is gamma vinyl GABA in an amount of about 100 mg/kg to about 300 mg/kg and the vitamin B6 is in amount of about 5 mg to about 300 mg.