Device for the optically controlled micro-manipulation of biological objects

Abstract

The invention relates to a device for the optically controlled micromanipulation of biological objects, containing the following: at least one micro manipulator comprising at least one holder that is motor-displaceable by means of Control elements for a cytological instrument; and a microscope, which has at least one functional element that is motor-displaceable by means of a control element. The motor-displaceable holder is coupled to at least one motor-displaceable functional clement in such a way that a mutual adjustment or setting of the holder and an adjustment of the functional element(s) of the microscope can be carded out in a co-ordinated manner by means of a common control element ( 17, 18 ).

1 . A device for optically controlled micro-manipulation of biological specimens having at least one micro-manipulator with at least one cytotechnical instrument holder that is motor-displaceable by means of control elements, and with a microscope, which has at least one functional element motor-displaceable by means of a control element, characterized in that the motor-displaceable holder is coupled with at least one motor-displaceable functional element of the microscope in such fashion that, by means of a common control element ( 17 ,  18 ), a common displacement or adjustment of the holder and a displacement of the at least one functional element of the microscope can be executed in a coordinated fashion.  
     
     
         2 . The device according to  claim 1 , characterized in that upon changing the size of the field of view ( 10 ,  10 ′) by changing the microscope objective lens ( 25 ,  25 ′), the covered range of displacement of the cytotechnical instrument ( 15 ) using the holder is adapted to the new field of view.  
     
     
         3 . The device according to  claim 2 , characterized in that for adapting the covered range of movement of the cytotechnical instrument ( 15 ) using the holder to the new size of the field of view, the transmission ratio of the control element ( 16 ) controlling the holder is correspondingly changed.  
     
     
         4 . The device according to  claim 1 , characterized in that with the displacement of the microscope objective ( 25 ,  25 ′) for the purpose of focussing a displacement of the holder in the z-direction takes place.  
     
     
         5 . The device according to  claim 1 , characterized in that with displacement of the microscope table or the microscope by means of a common control element, a corresponding displacement of at least one cytotechnical instrument of the at least one manipulator takes place.  
     
     
         6 . The device according to  claim 1 , characterized in that specific stored settings of one or a plurality of motor-displaceable functional elements of the microscope and of the manipulator can be refined and readjusted by actuation of a common control element.  
     
     
         7 . The device according to one of claims  1  -  6 , characterized in that the control elements ( 16 ,  17 ,  18 ) for adjusting or displacing the at least one motor-displaceable holder and/or of the at least one motor-displaceable functional element of the microscope is provided on an operator console ( 28 ).  
     
     
         8 . The device according to one of claims  1 - 7 , characterized in that two micro-manipulators are provided, whose holders can be adjusted or displaced in common with a functional element of the microscope by means of a common control element