US2004147998A1PendingUtilityA1

Differentially coated stent

52
Priority: Jan 24, 2003Filed: Jan 24, 2003Published: Jul 29, 2004
Est. expiryJan 24, 2023(expired)· nominal 20-yr term from priority
Inventors:John Nolting
A61L 2300/61Y10S623/901A61F 2/915A61F 2/91A61F 2002/91558A61L 31/16A61F 2250/0067A61F 2230/0013A61F 2002/91541A61L 31/10A61L 29/16A61L 29/085
52
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The present invention provides a stent that is differentially coated to accommodate areas of high strain. A therapeutic coating is applied to only those areas of the stent that do not experience high strain. This allows a therapeutic coating to be chosen for its elution characteristics, for example, rather than for its ability to withstand high strain. An elastic coating may be applied to the areas of high strain. The elastic coating may or may not include a therapeutic agent.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . A system for treating a vascular condition, comprising: 
 a catheter;    a stent coupled to the catheter, the stent including a stent framework, the stent framework including areas of high strain; and    a therapeutic coating disposed on at least a portion of the stent framework and avoiding the areas of high strain.    
     
     
         2 . The system of  claim 1  further comprising: 
 an elastic coating disposed on at least the high-strain areas of the stent framework.  
 
     
     
         3 . The system of  claim 2  wherein the therapeutic coating comprises a first polymer and the elastic coating comprises a second polymer.  
     
     
         4 . The system of  claim 1  wherein the therapeutic coating includes a therapeutic agent selected from a group consisting of an antineoplastic agent, an antiproliferative agent, an antibiotic, an antithrombogenic agent, an anticoagulant, an antiplatelet agent, and an anti-inflammatory agent.  
     
     
         5 . The system of  claim 2  wherein the elastic coating includes a therapeutic agent selected from a group consisting of an antineoplastic agent, an antiproliferative agent, an antibiotic, an antithrombogenic agent, an anticoagulant, an antiplatelet agent, and an anti-inflammatory agent.  
     
     
         6 . The system of  claim 2  wherein the therapeutic coating includes a first therapeutic agent and the elastic coating includes a second therapeutic agent.  
     
     
         7 . The system of  claim 2  wherein the therapeutic coating and the elastic coating display different elution characteristics.  
     
     
         8 . The system of  claim 2  wherein the therapeutic coating and the elastic coating display different durability characteristics.  
     
     
         9 . The system of  claim 1  wherein the catheter includes a balloon used to expand the stent.  
     
     
         10 . The system of  claim 1  wherein the catheter includes a sheath that retracts to allow expansion of the stent.  
     
     
         11 . A differentially coated stent, comprising: 
 a stent framework, the stent framework including areas of high strain; and    a therapeutic coating disposed on at least a portion of the stent framework and avoiding the areas of high strain.    
     
     
         12 . The stent of  claim 11  further comprising: 
 an elastic coating disposed on at least the areas of high strain.  
 
     
     
         13 . The stent of  claim 11  wherein the therapeutic coating includes an agent selected from a group consisting of an antineoplastic agent, an antiproliferative agent, an antibiotic, an antithrombogenic agent, an anticoagulant, an antiplatelet agent, and an anti-inflammatory agent.  
     
     
         14 . The stent of  claim 12  wherein the elastic coating includes a therapeutic agent selected from a group consisting of an antineoplastic agent, an antiproliferative agent, an antibiotic, an antithrombogenic agent, an anticoagulant, an antiplatelet agent, and an anti-inflammatory agent.  
     
     
         15 . The stent of  claim 12  wherein the therapeutic coating includes a first therapeutic agent and the elastic coating includes a second therapeutic agent.  
     
     
         16 . The stent of  claim 12  wherein the therapeutic coating and the elastic coating display different elution characteristics.  
     
     
         17 . The stent of  claim 12  wherein the therapeutic coating and the elastic coating display different durability characteristics.  
     
     
         18 . A method of manufacturing a differentially coated stent, comprising: 
 providing a stent framework, the stent framework including areas of high strain; and    applying a therapeutic coating to at least a portion of the stent framework, avoiding the areas of high strain.    
     
     
         19 . The method of  claim 18  wherein avoiding the areas of high strain comprises applying a therapeutic coating to only those areas of the stent framework that do not experience high strain.  
     
     
         20 . The method of  claim 18  wherein avoiding the areas of high strain comprises removing the therapeutic coating from high-strain areas of the stent framework.  
     
     
         21 . The method of  claim 18  wherein avoiding the areas of high strain comprises masking high-strain areas of the stent framework prior to applying a therapeutic coating.  
     
     
         22 . The method of  claim 21  wherein the stent framework is masked by one or more materials selected from a group consisting of a tetrafluorethylene sleeve, an adhesive-backed material, and a removable coating.  
     
     
         23 . The method of  claim 21  further comprising: 
 removing the masking material from the stent framework after the therapeutic coating is applied.  
 
     
     
         24 . The method of  claim 21  wherein the masking material is a protective polymer coating material.  
     
     
         25 . The method of  claim 24  wherein the protective polymer coating material is Parylene.  
     
     
         26 . The method of  claim 18  further comprising: 
 applying an elastic coating to at least the high-strain areas of the stent framework after applying the therapeutic coating.  
 
     
     
         27 . The method of  claim 26  further comprising: 
 masking the portion of the stent framework to which the therapeutic coating has been applied prior to applying the elastic coating.  
 
     
     
         28 . The method of  claim 18  further comprising: 
 applying an elastic coating to at least the high-strain areas of the stent framework prior to applying a therapeutic coating.  
 
     
     
         29 . The method of  claim 28  further comprising: 
 masking high-strain areas of the stent framework prior to applying the therapeutic coating.  
 
     
     
         30 . The method of  claim 18  wherein the therapeutic coating is applied by a method selected from the group consisting of pad printing, inkjet printing, rolling, painting, spraying, micro-spraying, dipping, wiping, electrostatic deposition, vapor deposition, epitaxial growth, and combinations thereof.  
     
     
         31 . The methods of claims  26  and  28  wherein the elastic coating is applied by a method selected from the group consisting of pad printing, inkjet printing, rolling, painting, spraying, micro-spraying, dipping, wiping, electrostatic deposition, vapor deposition, epitaxial growth, and combinations thereof.  
     
     
         32 . A system for producing a differentially coated stent, comprising: 
 means for providing a stent framework, the stent framework including areas of high strain; and    means for applying a therapeutic coating to at least a portion of the stent framework, avoiding the areas of high strain.    
     
     
         33 . The system of  claim 32  further comprising: 
 means for applying an elastic coating to at least the areas of high strain.

Join the waitlist — get patent alerts

Track US2004147998A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.