Wt1 modified peptide

Abstract

The present invention discloses a cancer antigen peptide comprising the following amino acid sequence: Cys Tyr Thr Trp Asn Gln Met Asn Leu (Sequence ID No. 3), a cancer vaccine having this for its active ingredient, and a DNA vaccine having for its active ingredient DNA that codes for this peptide.

1 . A cancer antigen peptide having for its active ingredient a peptide consisting of 9-30 amino acids and comprising the following amino acid sequence: Cys Tyr Thr Trp Asn Gln Met Asn Leu (Sequence ID No. 3).  
     
     
         2 . A cancer antigen peptide according to  claim 1  that is consisted of 9-12 amino acids and comprises the amino acid sequence indicated in Sequence ID No. 3.  
     
     
         3 . A cancer antigen peptide according to  claim 1  that is consisted of the amino acid sequence indicated in Sequence ID No. 3.  
     
     
         4 . A cancer vaccine having for its active ingredient a peptide according to any of claims  1  through  3 .  
     
     
         5 . A DNA vaccine against cancer having for its active ingredient DNA that codes for a peptide according to any of claims  1  through  3 .  
     
     
         6 . Antigen-presenting cells on which are presented a complex of HLA antigen and a peptide according to any of claims  1  through  3 .  
     
     
         7 . Cytotoxic T-cells that recognize a complex of HLA antigen and a peptide according to any of claims  1  through  3 .