Methods and compositions for topical wound treatment

Abstract

Compositions for improved treatment of wounds on a patient. A first composition having a safe and effective amount of lidocaine, wherein the composition is topically applied to a wound on a patient. A second composition having a safe and effective amount of lidocaine and a safe and effective amount of topical antibiotic, wherein the composition is topically applied to a wound on a patient. A method for treating a patient having a skin wound by locally administering a safe and effective amount of lidocaine and an antibiotic compound in the skin wound such that healing of the skin wound is enhanced.

What is claimed:  
     
         1 . A composition for use in the treatment of wounds, comprising a safe and effective amount of lidocaine in a carrier, wherein the composition is topically applied to a wound on a patient.  
     
     
         2 . The composition of  claim 1 , wherein the lidocaine comprises viscous lidocaine.  
     
     
         3 . The composition of  claim 1 , further comprising a safe and effective amount of a topical antibiotic compound.  
     
     
         4 . The composition of  claim 3 , wherein the topical antibiotic comprises chloramphenicol, chlortetracycline, clindamycin, erythromycin, gramicidin, gentamicin, metronidazole, mupiroicin, neomycin, polymyxin B, bacitracin, silver sulfadiazine, tetracycline, chlortetracycline, or combinations thereof.  
     
     
         5 . The composition of  claim 3 , wherein the topical antibiotic is polymyxin B sulfate.  
     
     
         6 . The composition of  claim 3 , wherein the topical antibiotic is polymyxin B sulfate and bacitracin zinc.  
     
     
         7 . The composition of  claim 1 , comprising from about 5 mg to about 40 mg lidocaine hydrochloride per gram of the composition.  
     
     
         8 . The composition of  claim 1 , further comprising a wax matrix.  
     
     
         9 . The composition of  claim 8 , wherein the wax matrix comprises Bag Balm®.  
     
     
         10 . The composition of  claim 8 , wherein the wax matrix comprises zinc oxide ointment.  
     
     
         11 . The composition of  claim 3 , comprising from about 5 mg to about 40 mg lidocaine hydrochloride and about 250 units to about 2000 units polymyxin B sulfate and about 10 units to about 100 units bacitracin zinc per gram of the composition.  
     
     
         12 . The composition of  claim 1 , further comprising oil of wintergreen.  
     
     
         13 . The composition of  claim 1 , further comprising one or more enzymes for debridement.  
     
     
         14 . A wound dressing comprising a bandage, a safe and effective amount of lidocaine in a carrier, wherein the wound dressing enhances healing of a wound.  
     
     
         15 . The wound dressing of  claim 14 , wherein the bandage comprises cotton, gauze, fiberglass or synthetic material.  
     
     
         16 . The wound dressing of  claim 14 , further comprising a safe and effective amount of a topical antibiotic compound.  
     
     
         17 . The wound dressing of  claim 14 , further comprising saline.  
     
     
         18 . The wound dressing of  claim 14 , further comprising a disinfectant component.  
     
     
         19 . A method for treating a patient having a skin wound, comprising locally administering a safe and effective amount of lidocaine in a carrier to the skin wound such that the healing of the skin wound is enhanced.  
     
     
         20 . The method of  claim 19 , further comprising locally administering a safe and effective amount of a topical antibiotic compound to the skin wound.  
     
     
         21 . The method of  claim 20 , further comprising covering the lidocaine and antibiotic compound in the skin wound with a dressing.  
     
     
         22 . The method of  claim 21 , wherein the dressing comprises cotton, gauze, fiberglass or synthetic material.  
     
     
         23 . The method of  claim 21 , wherein the dressing comprises a polymeric film.  
     
     
         24 . An article of manufacture comprising packaging material and a composition comprising a safe and effective amount of lidocaine in a carrier, wherein the packaging material comprises a label that indicates the composition is useful for treating a patient having a skin wound, and wherein local administration of the composition enhances healing of a skin wound.  
     
     
         25 . The article of manufacture of  claim 24 , wherein the composition further comprises a safe and effective amount of a topical antibiotic compound.  
     
     
         26 . A pre-packaged wound dressing contained in a package, comprising: 
 a safe and effective amount of lidocaine in a carrier;    a safe and effective amount of a topical antibiotic compound; and    a bandage configured to cover a wound.    
     
     
         27 . The pre-packaged wound dressing of  claim 26 , wherein the lidocaine and the antibiotic compound are contained in a storage container.  
     
     
         28 . The pre-packaged wound dressing of  claim 26 , wherein the bandage is coated on at least one side with the lidocaine and the antibiotic compound.  
     
     
         29 . A method for treating a patient having a skin wound, comprising: 
 applying a zinc oxide ointment around the exterior of the wound;    applying lidocaine and an antibiotic compound to a dressing;    applying the dressing to the wound; and    securing the dressing to the patient.    
     
     
         30 . The method of  claim 29 , further comprising placing a packing material containing lidocaine and an antibiotic compound directly in the wound.  
     
     
         31 . The method of  claim 29 , wherein securing the dressing comprises placing a polymer film over the dressing and utilizing the zinc oxide ointment surrounding the exterior of the wound to secure the polymer film to the patient.  
     
     
         32 . The method of  claim 29 , further comprising applying a saline solution to the dressing if the wound is dry.