Pharmaceutical or dietetic preparation for improvement of fertility and sperm quality

Abstract

Compositions for improving the fertility of and/or for improving the quality of semen produced by, a male mammal including a reduced folic acid, at least 13 mg zinc, and vitamin B12.

What is claimed is:  
     
         1 . Preparation or composition for improving the fertility of, and/or for improving the quality of the semen produced by, a male individual of a mammalian species, said composition comprising: 
 a reduced folic acid in an amount of between 0.4 and 5.5 mg;    at least one source of zinc in an amount of between 13 and 25 mg zinc; and    vitamin B12 in an amount of more than 1 μg per 400 μg of the reduced folic acid.    
     
     
         2 . Preparation or composition according to  claim 1 , wherein the reduced folic acid is selected from the group consisting of 5-formyl tetrahydrofolic acid (folinic acid), 5-methyl tetrahydrofolic acid, salts of these tetrahydrofolic acids, esters of these tetrahydrofolic acids and combinations thereof.  
     
     
         3 . Preparation or composition according to  claim 1 , comprising at least one further compound that supports methylation processes.  
     
     
         4 . Preparation or composition according to  claim 2  comprising at least one further compound that supports methylation processes.  
     
     
         5 . Preparation or composition according to  claim 3 , in which the compound that supports methylation processes is selected from the group consisting of magnesium, betaine, choline, SAM and vitamin B2.  
     
     
         6 . Preparation or composition according to  claim 4  wherein the compound that supports methylation processes is selected from the group consisting of magnesium, betaine, choline, SAM, and vitamin B2.  
     
     
         7 . Preparation or composition according to  claim 1 , further comprising between 1 and 10 g betaine equivalents.  
     
     
         8 . Preparation or composition according to  claim 1 , further comprising at least 1 mg vitamin B6.  
     
     
         9 . Preparation or composition according to  claim 1 , comprising Zinc 13-25 mg; Vit B12 >2 ug; Magnesium >50 mg; Copper >1 mg; Vit. B6 >1 mg; Methionine equivalents >0.3 mg; Betaine equivalents >0.3 mg.  
     
     
         10 . Preparation or composition according to  claim 1 , further comprising copper, the ratio of zinc to copper being in the range of 4-20.  
     
     
         11 . Preparation or composition according to  claim 1 , further comprising methionine equivalents in an amount between 0.6 and 6 g.  
     
     
         12 . Preparation or composition according to  claim 1 , wherein the reduced folic acid is in the form of an aqueous extract of a plant material.