US2004038942A1PendingUtilityA1

Medicament for treatment of bone marrow suppression, for treatment of infectious diseases and for increasing the number of leukocytes

Priority: Jan 16, 2001Filed: Jan 16, 2002Published: Feb 26, 2004

Est. expiryJan 16, 2021(expired)· nominal 20-yr term from priority

Inventors:Takumi Yamashita Chihiro Nishimura Tetsushi Saino Yasuhiko Muraoka Tomio Takeuchi

A61P 31/00A61P 43/00A61P 7/06A61P 39/02A61P 35/00A61P 7/00A61K 31/675A61P 19/08

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References

Claims

Abstract

A medicament for prophylaxis or treatment of bone marrow suppression, for treatment of infectious diseases and for increasing the number of leukocytes, which comprise as an active ingredient a sulphostin-related compound represented by general formula (I): wherein n is an integer of 0 to 3, or a pharmacologically acceptable salt thereof.

Claims

exact text as granted — not AI-modified

1 . A medicament for prophylaxis or treatment of bone marrow suppression comprising as an active ingredient a sulphostin-related compound represented by general formula (I):  
       
         
           
           
               
               
           
         
       
       wherein n is an integer of 0 to 3, or a pharmacologically acceptable salt thereof:  
     
     
         2 . A medicament according to  claim 1 , wherein n is an integer of 1 to 3 in general formula (I).  
     
     
         3 . A medicament according to  claim 1  or  2 , wherein the bone marrow suppression is leukopenia.  
     
     
         4 . A medicament for treatment of infectious diseases comprising as an active ingredient a sulphostin-related compound represented by general formula (I):  
       
         
           
           
               
               
           
         
       
       wherein n is an integer of 0 to 3, or a pharmacologically acceptable salt thereof.  
     
     
         5 . A medicament according to  claim 4 , wherein n is an integer of 1 to 3 in general formula (I).  
     
     
         6 . A medicament for increasing the number of leukocytes comprising as an active ingredient a sulphostin-related compound represented by general formula (I):  
       
         
           
           
               
               
           
         
       
       wherein n is an integer of 0 to 3, or a pharmacologically acceptable salt thereof.  
     
     
         7 . A medicament for increasing the number of leukocytes according to  claim 6 , wherein n is an integer of 1 to 3 in general formula (I).  
     
     
         8 . Use of a sulphostin-related compound represented by general formula (I):  
       
         
           
           
               
               
           
         
       
       wherein n is an integer of 0 to 3, or a pharmacologically acceptable salt thereof, for producing a medicament for prophylaxis or treatment of bone marrow suppression, for treatment of infectious diseases or for increasing the number of leukocytes.  
     
     
         9 . A method for prophylaxis or treatment of bone marrow suppression, for treatment of infectious diseases or for increasing the number of leukocytes, which comprises administering a sulphostin-related compound represented by general formula (I):  
       
         
           
           
               
               
           
         
       
       wherein n is an integer of 0 to 3, or a pharmacologically acceptable salt thereof, in a therapeutically effective amount.

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