Drugs against articular failure

Abstract

The object of the present invention is to provide a composition which exerts a higher effect on recovering health from articular disorders than that attained by amino sugars and glycosaminoglycans. The present invention solves the object by providing an agent for treating articular disorders, comprising an amino sugar and trehalose as effective ingredients.

1 . An agent for treating articular disorders, comprising an amino sugar and trehalose as effective ingredients.  
     
     
         2 . The agent of  claim 1 , wherein said amino sugar is one or more members selected from the group consisting of glucosamine, mannosamine, and a derivative thereof.  
     
     
         3 . The agent of  claim 2 , wherein said derivative is one or more members selected from the group consisting of acylated-, sulfated- and glycolylated-derivatives of amino sugars.  
     
     
         4 . The agent of any one of  claims 1  to  3 , which contains glucosamine and/or N-acetyl glucosamine as the amino sugar.  
     
     
         5 . The agent of any one of  claims 1  to  4 , which contains said trehalose in a weight ratio of at least one forth to said amino sugar, on a dry solid basis.  
     
     
         6 . The agent of any one of  claims 1  to  4 , which contains said trehalose in a weight ratio of at least one to said amino sugar, on a dry solid basis.  
     
     
         7 . The agent of any one of  claims 1  to  6 , which further contains a glycosaminoglycan.  
     
     
         8 . The agent of  claim 7 , wherein said glycosaminoglycan is one or more members selected from the group consisting of chondroitin sulfate, chondroitin, dermatan sulfate, heparin, heparan sulfate, keratan sulfate, and hyaluronic acid.  
     
     
         9 . The agent of any one of  claims 1  to  8 , which is used as an agent for preventing or alleviating arthritis or rheumatism.  
     
     
         10 . The agent of any one of  claims 1  to  9 , which contains said amino sugar in an amount of at least 0.1 but less than 15 mg per kilogram of human body weight per day.  
     
     
         11 . A composition in the form of a food, cosmetic, or pharmaceutical, comprising the agent of any one of  claims 1  to  8 .  
     
     
         12 . A composition in the form of a food, cosmetic, or pharmaceutical, comprising an amino sugar and trehalose.