Dressings and bandages comprising same

Abstract

The dressings of the invention comprise at least two components: an absorbent substrate having a first skin-facing surface and a second opposing surface; and a discontinuous coating of a semi-solid composition having an ointment-like feel overlying a portion of the first surface of said absorbent substrate. The absorbent substrate is useful as a passive dispenser of at least one active ingredient that may be contained therein. The discontinuous coating is essentially non-adherent to the skin and is useful as an active dispenser of at least one active ingredient that may be contained therein. In preferred embodiments the dressing of the invention contains at least one and more preferably at least two active ingredients intended to provide therapeutic benefit to the skin.

1 . A dressing comprising: 
 a. an absorbent substrate having a first skin-facing surface and a second opposing surface; and    b. a discontinuous coating of a semi-solid composition having an ointment-like feel overlying a portion of the first surface of said absorbent substrate; wherein    said absorbent substrate is useful as a passive dispenser of at least one active ingredient, said coating is substantially non-adherent to the skin, and said coating is useful as an active dispenser of at least one active ingredient.    
     
     
         2 . The dressing of  claim 1  wherein said discontinuous coating is configured in a regular pattern comprising elements selected from straight lines, angled lines, curved lines, intersecting lines, dots, circles and geometric shapes.  
     
     
         3 . The dressing of  claim 1  wherein said discontinuous coating is configured in a random pattern comprising elements selected from straight lines, angled lines, curved lines, intersecting lines, dots, circles and geometric shapes.  
     
     
         4 . The dressing of  claim 1  wherein said absorbent substrate is selected from woven fabric, knitted fabric nonwoven fabric and foam.  
     
     
         5 . The dressing of  claim 4  wherein said absorbent substrate comprises nonwoven fabric.  
     
     
         6 . The dressing of  claim 1  wherein said discontinuous coating is provided with one or more colors.  
     
     
         7 . The dressing of  claim 1  wherein said discontinuous coating overlies from about 1% to about 99% of the area of the first surface of said absorbent substrate.  
     
     
         8 . The dressing of  claim 7  wherein said discontinuous coating overlies from about 10% to about 90% of the area of the first surface of said absorbent substrate.  
     
     
         9 . The dressing of  claim 8  wherein said discontinuous coating overlies from about 20% to about 80% of the area of the first surface of said absorbent substrate.  
     
     
         10 . The dressing of  claim 1  which further comprises a porous covering material overlying said discontinuous coating.  
     
     
         11 . A dressing comprising: 
 a. an absorbent substrate having a first skin-facing surface and a second opposing surface;    b. a discontinuous coating of a semi-solid composition having an ointment-like feel overlying a portion of the first surface of said absorbent substrate; and    c. at least one active ingredient intended to deliver a therapeutic benefit to the skin; wherein    said absorbent substrate is useful as a passive dispenser of at least one active ingredient, said coating is substantially non-adherent to the skin, and said coating is useful as an active dispenser of at least one active ingredient.    
     
     
         12 . The dressing of  claim 11  wherein said at least one active ingredient is selected from antibiotics, analgesics, antipyretics, antimicrobials, antiseptics, antiallergics, anti-acne, anesthetics, anti-inflammatories, hemostats, cosmetics, vitamins, vasodilators, emollients, pH regulators, antipruritics, counterirritants, antihistamines and steroids.  
     
     
         13 . The dressing of  claim 11  wherein said at least one active ingredient selected from chlorhexidine, neomycin sulfate, polymyxin-B sulfate, zinc bacitracin, benzalkonium chloride, cetylpyridinium chloride, bupivacaine, tetracaine, cincaine, lidocaine, benzocaine, silver sulfadiazine, hydrocortisone, metandienone, trypsin, tolazoline, heparin, pramoxine, aloe vera, tretinoin, retinol, retinaldehyde, menthol, capsaicin, alpha hydroxy acids and Vitamin E and its derivatives.  
     
     
         14 . The dressing of  claim 11  wherein said at least one active ingredient is primarily contained in the absorbent substrate.  
     
     
         15 . The dressing of  claim 11  wherein said at least one active ingredient is primarily contained in the discontinuous coating.  
     
     
         16 . The dressing of  claim 11  wherein a portion of said at least one active ingredient is contained in said absorbent substrate and a portion of said at least one active ingredient is contained in said discontinuous coating.  
     
     
         17 . A dressing comprising: a. an absorbent substrate having a first skin-facing surface and a second opposing surface; 
 b. a discontinuous coating of a semi-solid composition having an ointment-like feel overlying a portion of the first surface of said absorbent substrate;    c. a first active ingredient contained substantially within said absorbent substrate; and    d. a second active ingredient contained substantially within said discontinuous coating; wherein    said absorbent substrate is useful as a passive dispenser of at least one active ingredient, said coating is substantially non-adherent to the skin, said coating is useful as an active dispenser of at least one active ingredient and said active ingredients are intended to deliver one or more therapeutic benefits to the skin.    
     
     
         18 . The dressing of  claim 17  wherein said active ingredients are selected from antibiotics, analgesics, antipyretics, antimicrobials, antiseptics, antiallergics, anti-acne, anesthetics, anti-inflammatories, hemostats, cosmetics, vitamins, vasodilators, emollients, pH regulators, antipruritics, counterirritants, antihistamines and steroids.  
     
     
         19 . The dressing of  claim 17  wherein said active ingredients are selected from chlorhexidine, neomycin sulfate, polymyxin-B sulfate, zinc bacitracin, benzalkonium chloride, cetylpyridinium chloride, bupivacaine, tetracaine, cincaine, lidocaine, benzocaine, silver sulfadiazine, hydrocortisone, metandienone, trypsin, tolazoline, heparin, pramoxine, aloe vera, tretinoin, retinol, retinaldehyde, menthol, capsaicin, alpha hydroxy acids and Vitamin E and its derivatives.  
     
     
         20 . The dressing of  claim 17  wherein said first active ingredient is an antiseptic and said second active ingredient is selected from antipruritics, antibiotics, anesthetics, anti-inflammatories or mixtures thereof.  
     
     
         21 . The dressing of  claim 20  wherein said second active ingredient is an antipruritic.  
     
     
         22 . The dressing of  claim 17  wherein said first active ingredient comprises benzalkonium chloride and said second active ingredient comprises aloe vera.  
     
     
         23 . The dressing of  claim 22  wherein said discontinuous coating further comprises Vitamin E or one or more of its derivatives.  
     
     
         24 . An adhesive bandage comprising: 
 a. an absorbent substrate having a first skin-facing surface and a second opposing surface; and    b. a discontinuous coating of a semi-solid composition having an ointment-like feel overlying a portion of the first surface of said absorbent substrate;    c. a backing material; and    d. a layer of adhesive on one surface of said backing material, said adhesive layer securing said absorbent substrate to said backing material; wherein    said absorbent substrate is useful as a passive dispenser of at least one active ingredient, said coating is substantially non-adherent to the skin, and said coating is useful as an active dispenser of at least one active ingredient.    
     
     
         25 . The bandage of  claim 24  wherein said discontinuous coating is configured in a regular pattern comprising elements selected from straight lines, angled lines, curved lines, intersecting lines, dots, circles and geometric shapes.  
     
     
         26 . The dressing of  claim 24  wherein said discontinuous coating is configured in a random pattern comprising elements selected from straight lines, angled lines, curved lines, intersecting lines, dots, circles and geometric shapes.  
     
     
         27 . The bandage of  claim 24  wherein said absorbent substrate is selected from woven fabric, knitted fabric nonwoven fabric and foam.  
     
     
         28 . The bandage of  claim 27  wherein said absorbent substrate comprises nonwoven fabric.  
     
     
         29 . The bandage of  claim 24  wherein said discontinuous coating overlies from about 1% to about 99% of the area of the first surface of said absorbent substrate.  
     
     
         30 . The bandage of  claim 29  wherein said discontinuous coating overlies from about 10% to about 90% of the area of the first surface of said absorbent substrate.  
     
     
         31 . The bandage of  claim 30  wherein said discontinuous coating overlies from about 20% to about 80% of the area of the first surface of said absorbent substrate.  
     
     
         32 . The bandage of  claim 24  which further comprises a porous covering material overlying said discontinuous coating.  
     
     
         33 . An adhesive bandage comprising: 
 a. an absorbent substrate having a first skin-facing surface and a second opposing surface;    b. a discontinuous coating of a semi-solid composition having an ointment-like feel overlying a portion of the first surface of said absorbent substrate;    c. at least one active ingredient intended to deliver a therapeutic benefit to the skin;    d. a backing material; and    e. a layer of adhesive on one surface of said backing material, said adhesive layer securing said absorbent substrate to said backing material; wherein    said absorbent substrate is useful as a passive dispenser of at least one active ingredient, said coating is substantially non-adherent to the skin, and said coating is useful as an active dispenser of at least one active ingredient.    
     
     
         34 . The bandage of  claim 33  wherein said at least one active ingredient is selected from antibiotics, analgesics, antipyretics, antimicrobials, antiseptics, antiallergics, anti-acne, anesthetics, anti-inflammatories, hemostats, cosmetics, vitamins, vasodilators, emollients, pH regulators, antipruritics, counterirritants, antihistamines and steroids.  
     
     
         35 . The bandage of  claim 33  wherein said at least one active ingredient selected from chlorhexidine, neomycin sulfate, polymyxin-B sulfate, zinc bacitracin, benzalkonium chloride, cetylpyridinium chloride, bupivacaine, tetracaine, cincaine, lidocaine, benzocaine, silver sulfadiazine, hydrocortisone, metandienone, trypsin, tolazoline, heparin, pramoxine, aloe vera, tretinoin, retinol, retinaldehyde, menthol, capsaicin, alpha hydroxy acids and Vitamin E and its derivatives.  
     
     
         36 . The bandage of  claim 33  wherein said at least one active ingredient is primarily contained in the absorbent substrate.  
     
     
         37 . The bandage of  claim 33  wherein said at least one active ingredient is primarily contained in the discontinuous coating.  
     
     
         38 . The bandage of  claim 33  wherein a portion of said at least one active ingredient is contained in said absorbent substrate and a portion of said at least one active ingredient is contained in said discontinuous coating.  
     
     
         39 . An adhesive bandage comprising: 
 a. an absorbent substrate having a first skin-facing surface and a second opposing surface;    b. a discontinuous coating of a semi-solid composition having an ointment-like feel overlying a portion of the first surface of said absorbent substrate;    c. a first active ingredient contained substantially within said absorbent substrate;    d. a second active ingredient contained substantially within said discontinuous coating;    e. a backing material; and    f. a layer of adhesive on one surface of said backing material, said adhesive layer securing said absorbent substrate to said backing material; wherein    said absorbent substrate is useful as a passive dispenser of at least one active ingredient, said coating is substantially non-adherent to the skin, said coating is useful as an active dispenser of at least one active ingredient and said active ingredients are intended to deliver one or more therapeutic benefits to the skin.    
     
     
         40 . The bandage of  claim 39  wherein said active ingredients are selected from antibiotics, analgesics, antipyretics, antimicrobials, antiseptics, antiallergics, anti-acne, anesthetics, anti-inflammatories, hemostats, cosmetics, vitamins, vasodilators, emollients, pH regulators, antipruritics, counterirritants, antihistamines and steroids.  
     
     
         41 . The bandage of  claim 39  wherein said active ingredients are selected from chlorhexidine, neomycin sulfate, polymyxin-B sulfate, zinc bacitracin, benzalkonium chloride, cetylpyridinium chloride, bupivacaine, tetracaine, cincaine, lidocaine, benzocaine, silver sulfadiazine, hydrocortisone, metandienone, trypsin, tolazoline, heparin, pramoxine, aloe vera, tretinoin, retinol, retinaldehyde, menthol, capsaicin, alpha hydroxy acids and Vitamin E and its derivatives.  
     
     
         42 . The bandage of  claim 39  wherein said first active ingredient is an antiseptic and said second active ingredient is selected from antipruritics, antibiotics, anesthetics, anti-inflammatories or mixtures thereof.  
     
     
         43 . The bandage of  claim 42  wherein said second active ingredient is an antipruritic.  
     
     
         44 . The bandage of  claim 39  wherein said first active ingredient comprises benzalkonium chloride and said second active ingredient comprises aloe vera.  
     
     
         45 . The bandage of  claim 44  wherein said discontinuous coating further comprises Vitamin E or one or more of its derivatives.