Product of heat treatment of uronic acid, food, drink or drug including the product

Abstract

A product obtained by heating at least one substance selected from the following (a), (b) and (c). (a) uronic acid or uronic acid derivative; (b) a saccharide compound containing uronic acid or a saccharide compound containing uronic acid derivative; and (c) a substance containing a saccharide compound containing uronic acid or a substance containing a saccharide compound containing uronic acid derivative; and food, beverage or a pharmaceutical agent which is characterized in containing the above-mentioned heat-treated product.

What is claimed is:  
     
         1 . A product obtained by heating at least one substance selected from the following (a), (b) and (c). 
 (a) uronic acid or uronic acid derivative;    (b) a saccharide compound containing uronic acid or a saccharide compound containing uronic acid derivative; and    (c) a substance containing a saccharide compound containing uronic acid or a substance containing a saccharide compound containing uronic acid derivative.    
     
     
         2 . A heat-treated product according to  claim 1  wherein uronic acid is galacturonic acid, glucuronic acid, guluronic acid, mannuronic acid and/or iduronic acid.  
     
     
         3 . A heat-treated product according to  claim 1  wherein the derivative is uronic acid lactone, uronic acid ester, uronic acid amide or salt thereof.  
     
     
         4 . A heat-treated product according to  claim 1  wherein the saccharide compound is a saccharide compound which is selected from pectin, pectic acid, alginic acid, hyaluronic acid, heparin, fucoidan, chondroitin sulfate, chondroitin, dermatan sulfate and/or decomposed product thereof.  
     
     
         5 . A heat-treated product according to any of claims  1 - 4  wherein the heat-treated product is obtained by heating at 60-350° C. for several seconds to several days.  
     
     
         6 . A heat-treated product according to any of claims  1 - 5  wherein the heat-treated product is obtained by heating under acidic to neutral conditions.  
     
     
         7 . A heat-treated product according to any of claims  1 - 6  wherein the heat-treated product is a product obtained by means of a molecular weight fractionation.  
     
     
         8 . Food or beverage which is characterized in containing the heat-treated product mentioned in any of claims  1 - 7 .  
     
     
         9 . Food or beverage according to  claim 8  which is prepared by adding and/or diluting the heat-treated product of any of claims  1 - 7 .  
     
     
         10 . Food having an anticancer action or beverage having an anticancer action which is characterized in containing the heat-treated product mentioned in any of claims  1 - 7 .  
     
     
         11 . Antibacterial agent which is characterized in containing any of the heat-treated product mentioned in any of claims  1 - 7 .  
     
     
         12 . Antiseptic agent which is characterized in containing the antibacterial agent of  claim 11 .  
     
     
         13 . Dentifrice which is characterized in containing the antibacterial agent of  claim 11 .  
     
     
         14 . An apoptosis-inducer which is characterized in containing the heat-treated product of claim  1 - 7 .  
     
     
         15 . An anticancer agent which is characterized in containing the heat-treated product of claim  1 - 7 .  
     
     
         16 . An inducer for differentiation of cancerous cells which is characterized in containing the heat-treated product of claim  1 - 7 .  
     
     
         17 . Antiulcer agent which is characterized in containing the heat-treated product of claim  1 - 7 .  
     
     
         18 . A method of inducing an apoptosis which is characterized in using the heat-treated product of claim  1 - 7  as an effective component.  
     
     
         19 . A method for the manufacture of a heat-treated product, characterized in that, said method includes a step of heating at least one substance selected from the following (a), (b) and (c). 
 (a) uronic acid or uronic acid derivative;    (b) a saccharide compound containing uronic acid or a saccharide compound containing uronic acid derivative; and    (c) a substance containing a saccharide compound containing uronic acid or a substance containing a saccharide compound containing uronic acid derivative.    
     
     
         20 . A method for the manufacture of the heat-treated product according to  claim 19  wherein uronic acid is galacturonic acid, glucuronic acid, guluronic acid, mannuronic acid and/or iduronic acid.  
     
     
         21 . A method for the manufacture of the heat-treated product according to  claim 19  wherein the derivative is uronic acid lactone, uronic acid ester, uronic acid amide or salt thereof.  
     
     
         22 . A method for the manufacture of the heat-treated product according to  claim 19  wherein the saccharide compound is a saccharide compound which is selected from pectin, pectic acid, alginic acid, hyaluronic acid, heparin, fucoidan, chondroitin sulfate, chondroitin, dermatan sulfate and/or decomposed product thereof.  
     
     
         23 . A method for the manufacture of the heat-treated product according to any of claims  19 - 22  wherein the heating is a treatment which is conducted at 60-350° C. for several seconds to several days.  
     
     
         24 . A method for the manufacture of the heat-treated product according to any of claims  19 - 23  wherein the heating is a treatment which is conducted under acidic to neutral conditions.  
     
     
         25 . A method for the manufacture of the heat-treated product according to any of claims  19 - 24  wherein a step of conducting a molecular weight fractionation of the heat-treated product is included.