US2003175781A1PendingUtilityA1

Method for controlling quality in the construction of oligomer arrays

58
Priority: Sep 15, 1998Filed: Mar 6, 2003Published: Sep 18, 2003
Est. expirySep 15, 2018(expired)· nominal 20-yr term from priority
Inventors:Markus Beier
C12Q 1/6837B01J 2219/00722B01J 2219/0072C40B 40/06B01J 2219/00605B01J 19/0046C40B 80/00B01J 2219/00659B01J 2219/00637B01J 2219/00693B01J 2219/00626
58
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Claims

Abstract

The present invention relates to a method for conrolling the quality of oligomer assays, which is characterized in that a phosphate unit is fused to certain array positions, said phosphate unit being linked to a signal-generating reporter group, the degree of oligomer synthesis is determined using the signal of the reporter group, and the reporter group is then split off again.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . A cleavable label for controlling the quality of oligomer arrays comprises a phosphate unit and a signal-generating reporter group, wherein the signal generating reporting group is covalently bound to the phosphate unit and is cleavable.  
     
     
         2 . The cleavable label according to  claim 1 , wherein the signal-generating reporter group is a fluorescent group.  
     
     
         3 . The cleavable label according to  claim 1 , wherein the signal-generating reporter group is covalently bound to the phosphate via a linker.

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