Urogenital carcinoma tlp complex peptides and antibodies thereof

Abstract

It is described a peptide comprising a specific urogenital carcinoma TLP epitope, wherein the TLP comprises the aminoacid sequence: GlyProProGluValGlnAsnAlaAsn. Also described are reagents to detect said urogenital TLPs and pharmaceutical compositions.

1 . Peptide comprising a TLP urogenital specific epitope, wherein said TLP comprises the amino acid sequence of SEQ ID No. 1.  
     
     
         2 . Peptide according to  claim 1  comprising the amino acid sequence of SEQ ID NO. 1.  
     
     
         3 . Antibody able to recognise at least one peptide according to  claim 1  or  2 .  
     
     
         4 . Diagnostic kit to identify TLP from urogenital tumoral samples comprising as specific reagent the antibody according to  claim 3 .  
     
     
         5 . Process to identify TLP complexes from urogenital tumoral samples characterised by the fact of comprising the following steps: 
 to immunoprecipitate said sample with a first aliquot of immune serum against the peptide of  claim 1  or  2 ;    to detect said TLP complexes from the first immunoprecipitate by means of a reaction with a second aliquot of said immune serum and with a detecting mean of said reaction.    
     
     
         6 . Pharmaceutical composition comprising as active agent the peptide of  claim 1.