US2003155294A1PendingUtilityA1

Filter device, preferably a hollow fibre dialyser, comprising curled hollow fibres

Priority: Feb 17, 2000Filed: Feb 16, 2001Published: Aug 21, 2003
Est. expiryFeb 17, 2020(expired)· nominal 20-yr term from priority
B01D 61/28B01D 69/08B01D 2313/08B01D 69/00B01D 65/00B01D 69/084B01D 63/021B01D 63/031
40
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Claims

Abstract

The invention relates to a filter device, preferably for hemodialysis, that consists of a cylindrical filter housing and a bundle of curled hollow fibers. The bundle is arranged in the filter housing. According to the invention, the curled hollow fibers are provided with an essentially sinusoidal texture and a wavelength that is defined by means of certain limits. The invention also relates to a curled hollow fiber and a method for filling a hollow fiber dialyser.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . Filter device, preferably a hollow fiber dialyser for hemodialysis, consisting of a cylindrical filter housing and a bundle of curled hollow fibers arranged in it, characterized in that the hollow fibers have an essentially sinusoidal texture and are curled according to the following geometric pattern:  
       
         
           
             
               
                 
                   
                     
                       
                         5 
                         · 
                         d 
                       
                       < 
                       λ 
                       < 
                       
                         
                           L 
                           12 
                         
                         · 
                         
                           1 
                           
                             1 
                             + 
                             
                               2 
                                
                               
                                 D 
                                 L 
                               
                             
                           
                         
                       
                     
                     , 
                   
                 
                 
                   
                     ( 
                     1 
                     ) 
                   
                 
               
             
           
           
           
               
           
         
       
       whereby λ represents the wavelength of the curled hollow fiber, 
 d represents the outer diameter of the hollow fiber,  
 L represents the effective length of the hollow fiber, and  
 D represents the diameter of the fiber bundle.  
 
     
     
         2 . Filter device according to  claim 1 , characterized in that amplitude a of the essentially sinusoidal curling results from the following equation:  
       
         
           
             
               
                 
                   
                     
                       d 
                       5 
                     
                     < 
                     a 
                     < 
                     
                       
                         λ 
                         5 
                       
                       . 
                     
                   
                 
                 
                   
                     ( 
                     2 
                     ) 
                   
                 
               
             
           
           
           
               
           
         
       
     
     
         3 . Filter device according to claims  1  or  2 , characterized in that the curling of the hollow fiber has a three-dimensional position according to the following formula:  
       
         
           
             
               
                 
                   
                     
                       
                         
                           x 
                           ⇀ 
                         
                          
                         
                           ( 
                           z 
                           ) 
                         
                       
                       = 
                       
                         ( 
                         
                           
                             
                               
                                 a 
                                 · 
                                 
                                   sin 
                                    
                                   
                                     ( 
                                     
                                       
                                         
                                           2 
                                            
                                           π 
                                            
                                           
                                               
                                           
                                            
                                           z 
                                         
                                         λ 
                                       
                                       · 
                                       u 
                                     
                                     ) 
                                   
                                 
                                 · 
                                 
                                   sin 
                                    
                                   
                                     ( 
                                     
                                       
                                         2 
                                          
                                         π 
                                          
                                         
                                             
                                         
                                          
                                         z 
                                       
                                       λ 
                                     
                                     ) 
                                   
                                 
                               
                             
                           
                           
                             
                               
                                 a 
                                 · 
                                 
                                   cos 
                                    
                                   
                                     ( 
                                     
                                       
                                         
                                           2 
                                            
                                           π 
                                            
                                           
                                               
                                           
                                            
                                           z 
                                         
                                         λ 
                                       
                                       · 
                                       u 
                                     
                                     ) 
                                   
                                 
                                 · 
                                 
                                   sin 
                                    
                                   
                                     ( 
                                     
                                       
                                         2 
                                          
                                         π 
                                          
                                         
                                             
                                         
                                          
                                         z 
                                       
                                       λ 
                                     
                                     ) 
                                   
                                 
                               
                             
                           
                           
                             
                               
                                 
                                     
                                 
                                  
                                 z 
                               
                             
                           
                         
                         ) 
                       
                     
                     , 
                   
                 
                 
                   
                     ( 
                     3 
                     ) 
                   
                 
               
             
           
           
           
               
           
         
       
       whereby the following is true: 
 0.05<u<0.14, and whereby 
 {overscore (χ)}(z) represents the space vector between the coordinate origin and the spatial position of a hollow fiber that extends along the z-axis, and  
 u represents the amount of rotations per wavelength λ.  
 
 
     
     
         4 . Filter device according to one of the  claims 1  to  3 , characterized in that the fiber allocation in the cylindrical filter housing is 60.5% to 70%.  
     
     
         5 . Filter device according to one of the  claims 1  to  4 , characterized in that the fiber allocation in the cylindrical filter housing is 60.5% to 67.5%.  
     
     
         6 . Filter device according to one of the  claims 1  to  5 , characterized in that the fiber allocation in the cylindrical filter housing is between 63.5% and 65.5%.  
     
     
         7 . Filter device according to one of the  claims 1  to  6 , characterized in that at least 10% of the hollow fibers are three-dimensional curled hollow fibers.  
     
     
         8 . Curled hollow fiber for optional use in the shape of a bundle in filter devices, preferably hollow fiber dialysers, which may have various diameters D, from a minimum diameter D MIN  up to a maximum diameter D MAX , characterized in that the curled hollow fiber has only one curl for the use in filter housings of various diameters, resulting from the following equations:  
       
         
           
             
               
                 
                   
                     
                       
                         5 
                         · 
                         d 
                       
                       < 
                       λ 
                       < 
                       
                         
                           L 
                           12 
                         
                         · 
                         
                           1 
                           
                             1 
                             + 
                             
                               2 
                                
                               
                                 DMax 
                                 L 
                               
                             
                           
                         
                       
                     
                     , 
                   
                 
                 
                   
                     ( 
                     4 
                     ) 
                   
                 
               
             
           
           
           
               
           
         
       
       whereby λ represents the wavelength of the curled hollow fiber, 
 d represents the outer diameter of the hollow fiber,  
 L represents the effective length of the hollow fibers, and  
 D MAX  represents the diameter of the fiber bundle for the fiber housing with the maximum interior diameter.  
 
     
     
         9 . Curled hollow fiber according to  claim 8 , characterized in that the curling of the hollow fiber has a three-dimensional position according to the following formula:  
       
         
           
             
               
                 
                   
                     
                       
                         
                           x 
                           ⇀ 
                         
                          
                         
                           ( 
                           z 
                           ) 
                         
                       
                       = 
                       
                         ( 
                         
                           
                             
                               
                                 a 
                                 · 
                                 
                                   sin 
                                    
                                   
                                     ( 
                                     
                                       
                                         
                                           2 
                                            
                                           π 
                                            
                                           
                                               
                                           
                                            
                                           z 
                                         
                                         λ 
                                       
                                       · 
                                       u 
                                     
                                     ) 
                                   
                                 
                                 · 
                                 
                                   sin 
                                    
                                   
                                     ( 
                                     
                                       
                                         2 
                                          
                                         π 
                                          
                                         
                                             
                                         
                                          
                                         z 
                                       
                                       λ 
                                     
                                     ) 
                                   
                                 
                               
                             
                           
                           
                             
                               
                                 a 
                                 · 
                                 
                                   cos 
                                    
                                   
                                     ( 
                                     
                                       
                                         
                                           2 
                                            
                                           π 
                                            
                                           
                                               
                                           
                                            
                                           z 
                                         
                                         λ 
                                       
                                       · 
                                       u 
                                     
                                     ) 
                                   
                                 
                                 · 
                                 
                                   sin 
                                    
                                   
                                     ( 
                                     
                                       
                                         2 
                                          
                                         π 
                                          
                                         
                                             
                                         
                                          
                                         z 
                                       
                                       λ 
                                     
                                     ) 
                                   
                                 
                               
                             
                           
                           
                             
                               
                                 
                                     
                                 
                                  
                                 z 
                                  
                                 
                                     
                                 
                               
                             
                           
                         
                         ) 
                       
                     
                     , 
                   
                 
                 
                   
                     ( 
                     3 
                     ) 
                   
                 
               
             
           
           
           
               
           
         
       
       whereby the following is true: 
 0.05<u<0.14, and whereby {overscore (χ)}(z) represents the space vector between the coordinate origin and the spatial position of a hollow fiber that extends along the z-axis, and u represents the amount of rotations per wavelength λ.  
 
     
     
         10 . Curled hollow fiber according to claims  8  or  9 , characterized in that it consists of 90 to 99 weight percent of a hydrophobic first polymer, and 10 to 1 weight percent of a hydrophilic second polymer, whereby the hydrophobic first polymers are selected from the following group: polyarylsulfons, polycarbonates, polyamides, polyvinyl chlorides, modified acrylic acid, polyether, polyurethane, or their co-polymers, and whereby the hydrophilic second polymers are selected from the following group: polyvinylpyrrolidon, polyethylene glycol, polyglycolmonoesther, co-polymers from polyethylene glycol with polypropylenglycol, water soluble derivatives of cellulose or polysorbates.  
     
     
         11 . Method for the filling of a filter device, especially a hollow fiber dialyser, according to one of the  claims 1  to  7 , characterized in that the air present at the beginning of the filling operation in the exterior space, i.e., in the space surrounding the hollow fibers, is displaced by means of a fluid volume flow that is guided from top to bottom through the filter housing.  
     
     
         12 . Method according to  claim 11 , characterized in that the fluid volume flow is approximately 500 ml/min.  
     
     
         13 . Use of a filter device according to one of the  claims 1  to  7  for the filling of the filter housing by means of a fluid volume flow that is guided from top to bottom through the filter housing.

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