US2003148964A1PendingUtilityA1
Single dose azithromycin
Priority: Aug 21, 2001Filed: Aug 21, 2002Published: Aug 7, 2003
Est. expiryAug 21, 2021(expired)· nominal 20-yr term from priority
Inventors:Michael Dunne
A61P 27/16A61P 31/04A61K 31/7052A61P 11/00
45
PatentIndex Score
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Cited by
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Claims
Abstract
The present invention relates to a method of treating infections in humans by administering a single dose of azithromycin.
Claims
exact text as granted — not AI-modified1 . A method of treating a respiratory infection in a human comprising administering to a human in need thereof a single dose of azithromycin wherein the dose is about 30 mg/kg body weight or greater.
2 . The method of claim 1 wherein the dose is about 31 mg/kg body weight or greater.
3 . The method of claim 1 wherein the dose is about 50 mg/kg body weight or greater.
4 . The method of claim 1 wherein the dose is about 70 mg/kg body weight or greater.
5 . The method of claim 1 wherein the dose is between about 30 mg/kg and 90 mg/kg body weight.
6 . The method of claim 1 wherein the dose is between about 30 mg/kg and 35 mg/kg body weight.
7 . The method of claim 1 wherein the dose is between about 31 mg/kg and 35 mg/kg body weight.
8 . The method of claim 1 wherein the dose is between about 35 mg/kg and 40 mg/kg body weight.
9 . The method of claim 1 wherein the dose is between about 40 mg/kg and 45 mg/kg body weight.
10 . The method of claim 1 wherein the dose is between about 45 mg/kg and 50 mg/kg body weight.
11 . The method of claim 1 wherein the dose is between about 50 mg/kg and 55 mg/kg body weight.
12 . The method of claim 1 wherein the dose is between about 55 mg/kg and 60 mg/kg body weight.
13 . The method of claim 1 wherein the dose is between about 60 mg/kg and 65 mg/kg body weight.
14 . The method of claim 1 wherein the dose is between about 65 mg/kg and 70 mg/kg body weight.
15 . The method of claim 1 wherein the dose is between about 70 mg/kg and 75 mg/kg body weight.
16 . The method of claim 1 wherein the dose is between about 75 mg/kg and 80 mg/kg body weight.
17 . The method of claim 1 wherein the dose is between about 80 mg/kg and 85 mg/kg body weight.
18 . The method of claim 1 wherein the dose is between about 85 mg/kg and 90 mg/kg body weight.
19 . The method of claim 1 wherein the human is an adult sixteen years of age or older.
20 . The method of claim 1 wherein the respiratory infection is acute otitis media.
21 . A method of treating a respiratory infection in a human comprising administering to a human in need thereof a single dose of azithromycin wherein the dose is within the range of about 0.15 to 4.5 g.
22 . The method of claim 21 wherein the respiratory infection is acute otitis media.
23 . The method of claim 21 wherein the dose is within the range of about 0.15 to 1.5 g.
24 . The method of claim 21 wherein the dose is within the range of about 1.5 to 2.5 g.
25 . The method of claim 21 wherein the dose is within the range of about 2.5 to 3.5 g.
26 . The method of claim 21 wherein the dose is within the range of about 3.5 to 4.5 g.
27 . The method of claim 21 wherein the human is an adult sixteen years of age or older.
28 . A method of treating a respiratory infection caused by S. pneumoniae in a human comprising administering to a human in need thereof a single dose of azithromycin wherein the dose is about 30 mg/kg body weight or greater.
29 . The method of claim 28 wherein the human is an adult sixteen years of age or older.
30 . The method of claim 28 wherein the respiratory infection is acute otitis media.
31 . The method of claim 28 wherein the dose is about 31 mg/kg body weight or greater.
32 . The method of claim 28 wherein the dose is about 50 mg/kg body weight or greater.
33 . The method of claim 28 wherein the dose is about 70 mg/kg body weight or greater.
34 . The method of claim 28 wherein the dose is between about 30 mg/kg and 90 mg/kg body weight.
35 . The method of claim 28 wherein the dose is between about 30 mg/kg and 35 mg/kg body weight.
36 . The method of claim 28 wherein the dose is between about 31 mg/kg and 35 mg/kg body weight.
37 . The method of claim 28 wherein the dose is between about 35 mg/kg and 40 mg/kg body weight.
38 . The method of claim 28 wherein the dose is between about 40 mg/kg and 45 mg/kg body weight.
39 . The method of claim 28 wherein the dose is between about 45 mg/kg and 50 mg/kg body weight.
40 . The method of claim 28 wherein the dose is between about 50 mg/kg and 55 mg/kg body weight.
41 . The method of claim 28 wherein the dose is between about 55 mg/kg and 60 mg/kg body weight.
42 . The method of claim 28 wherein the dose is between about 60 mg/kg and 65 mg/kg body weight.
43 . The method of claim 28 wherein the dose is between about 65 mg/kg and 70 mg/kg body weight.
44 . The method of claim 28 wherein the dose is between about 70 mg/kg and 75 mg/kg body weight.
45 . The method of claim 28 wherein the dose is between about 75 mg/kg and 80 mg/kg body weight.
46 . The method of claim 28 wherein the dose is between about 80 mg/kg and 85 mg/kg body weight.
47 . The method of claim 28 wherein the dose is between about 85 mg/kg and 90 mg/kg body weight.
48 . The method of claim 28 wherein the respiratory infection is caused by an S. pneumoniae isolate containing a mef A gene.
49 . The method of claim 48 wherein the human is an adult sixteen years of age or older.
50 . The method of claim 48 wherein the respiratory infection is acute otitis media.
51 . The method of claim 48 wherein the dose is about 31 mg/kg body weight or greater.
52 . The method of claim 48 wherein the dose is about 50 mg/kg body weight or greater.
53 . The method of claim 48 wherein the dose is about 70 mg/kg body weight or greater.
54 . The method of claim 48 wherein the dose is between about 30 mg/kg and 90 mg/kg body weight.
55 . The method of claim 48 wherein the dose is between about 30 mg/kg and 35 mg/kg body weight.
56 . The method of claim 48 wherein the dose is between about 31 mg/kg and 35 mg/kg body weight.
57 . The method of claim 48 wherein the dose is between about 35 mg/kg and 40 mg/kg body weight.
58 . The method of claim 48 wherein the dose is between about 40 mg/kg and 45 mg/kg body weight.
59 . The method of claim 48 wherein the dose is between about 45 mg/kg and 50 mg/kg body weight.
60 . The method of claim 48 wherein the dose is between about 50 mg/kg and 55 mg/kg body weight.
61 . The method of claim 48 wherein the dose is between about 55 mg/kg and 60 mg/kg body weight.
62 . The method of claim 48 wherein the dose is between about 60 mg/kg and 65 mg/kg body weight.
63 . The method of claim 48 wherein the dose is between about 65 mg/kg and 70 mg/kg body weight.
64 . The method of claim 48 wherein the dose is between about 70 mg/kg and 75 mg/kg body weight.
65 . The method of claim 48 wherein the dose is between about 75 mg/kg and 80 mg/kg body weight.
66 . The method of claim 48 wherein the dose is between about 80 mg/kg and 85 mg/kg body weight.
67 . The method of claim 48 wherein the dose is between about 85 mg/kg and 90 mg/kg body weight.
68 . A method of treating a respiratory infection caused by H. influenzae in a human comprising administering to a human in need thereof a single dose of azithromycin wherein the dose is about 30 mg/kg body weight or greater.
69 . The method of claim 68 wherein the human is an adult sixteen years of age or older.
70 . The method of claim 68 wherein the respiratory infection is acute otitis media.
71 . The method of claim 68 wherein the dose is about 31 mg/kg body weight or greater.
72 . The method of claim 68 wherein the dose is about 50 mg/kg body weight or greater.
73 . The method of claim 68 wherein the dose is about 70 mg/kg body weight or greater.
74 . The method of claim 68 wherein the dose is between about 30 mg/kg and 90 mg/kg body weight.
75 . The method of claim 68 wherein the dose is between about 30 mg/kg and 35 mg/kg body weight.
76 . The method of claim 68 wherein the dose is between about 31 mg/kg and 35 mg/kg body weight.
77 . The method of claim 68 wherein the dose is between about 35 mg/kg and 40 mg/kg body weight.
78 . The method of claim 68 wherein the dose is between about 40 mg/kg and 45 mg/kg body weight.
79 . The method of claim 68 wherein the dose is between about 45 mg/kg and 50 mg/kg body weight.
80 . The method of claim 68 wherein the dose is between about 50 mg/kg and 55 mg/kg body weight.
81 . The method of claim 68 wherein the dose is between about 55 mg/kg and 60 mg/kg body weight.
82 . The method of claim 68 wherein the dose is between about 60 mg/kg and 65 mg/kg body weight.
83 . The method of claim 68 wherein the dose is between about 65 mg/kg and 70 mg/kg body weight.
84 . The method of claim 68 wherein the dose is between about 70 mg/kg and 75 mg/kg body weight.
85 . The method of claim 68 wherein the dose is between about 75 mg/kg and 80 mg/kg body weight.
86 . The method of claim 68 wherein the dose is between about 80 mg/kg and 85 mg/kg body weight.
87 . The method of claim 68 wherein the dose is between about 85 mg/kg and 90 mg/kg body weight.
88 . A method of treating an infection caused by S. pyogenes in a human comprising administering to a human in need thereof a single dose of azithromycin wherein the dose is about 30 mg/kg body weight or greater.
89 . The method of claim 88 wherein the human is an adult sixteen years of age or older.
90 . The method of claim 88 wherein the infection is a respiratory infection.
91 . The method of claim 88 wherein the dose is about 31 mg/kg body weight or greater.
92 . The method of claim 88 wherein the dose is about 50 mg/kg body weight or greater.
93 . The method of claim 88 wherein the dose is about 70 mg/kg body weight or greater.
94 . The method of claim 88 wherein the dose is between about 30 mg/kg and 90 mg/kg body weight.
95 . The method of claim 88 wherein the dose is between about 30 mg/kg and 35 mg/kg body weight.
96 . The method of claim 88 wherein the dose is between about 31 mg/kg and 35 mg/kg body weight.
97 . The method of claim 88 wherein the dose is between about 35 mg/kg and 40 mg/kg body weight.
98 . The method of claim 88 wherein the dose is between about 40 mg/kg and 45 mg/kg body weight.
99 . The method of claim 88 wherein the dose is between about 45 mg/kg and 50 mg/kg body weight.
100 . The method of claim 88 wherein the dose is between about 50 mg/kg and 55 mg/kg body weight.
101 . The method of claim 88 wherein the dose is between about 55 mg/kg and 60 mg/kg body weight.
102 . The method of claim 88 wherein the dose is between about 60 mg/kg and 65 mg/kg body weight.
103 . The method of claim 88 wherein the dose is between about 65 mg/kg and 70 mg/kg body weight.
104 . The method of claim 88 wherein the dose is between about 70 mg/kg and 75 mg/kg body weight.
105 . The method of claim 88 wherein the dose is between about 75 mg/kg and 80 mg/kg body weight.
106 . The method of claim 88 wherein the dose is between about 80 mg/kg and 85 mg/kg body weight.
107 . The method of claim 88 wherein the dose is between about 85 mg/kg and 90 mg/kg body weight.
108 . A method of treating an infection caused by E. faecalis in a human comprising administering to a human in need thereof a single dose of azithromycin wherein the dose is about 30 mg/kg body weight or greater.
109 . The method of claim 108 wherein the human is an adult sixteen years of age or older.
110 . The method of claim 108 wherein the infection is a urinary tract infection.
111 . The method of claim 108 wherein the dose is about 31 mg/kg body weight or greater.
112 . The method of claim 108 wherein the dose is about 50 mg/kg body weight or greater.
113 . The method of claim 108 wherein the dose is about 70 mg/kg body weight or greater.
114 . The method of claim 108 wherein the dose is between about 30 mg/kg and 90 mg/kg body weight.
115 . The method of claim 108 wherein the dose is between about 30 mg/kg and 35 mg/kg body weight.
116 . The method of claim 108 wherein the dose is between about 31 mg/kg and 35 mg/kg body weight.
117 . The method of claim 108 wherein the dose is between about 35 mg/kg and 40 mg/kg body weight.
118 . The method of claim 108 wherein the dose is between about 40 mg/kg and 45 mg/kg body weight.
119 . The method of claim 108 wherein the dose is between about 45 mg/kg and 50 mg/kg body weight.
120 . The method of claim 108 wherein the dose is between about 50 mg/kg and 55 mg/kg body weight.
121 . The method of claim 108 wherein the dose is between about 55 mg/kg and 60 mg/kg body weight.
122 . The method of claim 108 wherein the dose is between about 60 mg/kg and 65 mg/kg body weight.
123 . The method of claim 108 wherein the dose is between about 65 mg/kg and 70 mg/kg body weight.
124 . The method of claim 108 wherein the dose is between about 70 mg/kg and 75 mg/kg body weight.
125 . The method of claim 108 wherein the dose is between about 75 mg/kg and 80 mg/kg body weight.
126 . The method of claim 108 wherein the dose is between about 80 mg/kg and 85 mg/kg body weight.
127 . The method of claim 108 wherein the dose is between about 85 mg/kg and 90 mg/kg body weight.
128 . A method of treating a respiratory infection caused by M. catarrhalis in a human comprising administering to a human in need thereof a single dose of azithromycin wherein the dose is about 30 mg/kg body weight or greater.
129 . The method of claim 128 wherein the human is an adult sixteen years of age or older.
130 . The method of claim 128 wherein the respiratory infection is acute otitis media.
131 . The method of claim 128 wherein the dose is about 31 mg/kg body weight or greater.
132 . The method of claim 128 wherein the dose is about 50 mg/kg body weight or greater.
133 . The method of claim 128 wherein the dose is about 70 mg/kg body weight or greater.
134 . The method of claim 128 wherein the dose is between about 30 mg/kg and 90 mg/kg body weight.
135 . The method of claim 128 wherein the dose is between about 30 mg/kg and 35 mg/kg body weight.
136 . The method of claim 128 wherein the dose is between about 31 mg/kg and 35 mg/kg body weight.
137 . The method of claim 128 wherein the dose is between about 35 mg/kg and 40 mg/kg body weight.
138 . The method of claim 128 wherein the dose is between about 40 mg/kg and 45 mg/kg body weight.
139 . The method of claim 128 wherein the dose is between about 45 mg/kg and 50 mg/kg body weight.
140 . The method of claim 128 wherein the dose is between about 50 mg/kg and 55 mg/kg body weight.
141 . The method of claim 128 wherein the dose is between about 55 mg/kg and 60 mg/kg body weight.
142 . The method of claim 128 wherein the dose is between about 60 mg/kg and 65 mg/kg body weight.
143 . The method of claim 128 wherein the dose is between about 65 mg/kg and 70 mg/kg body weight.
144 . The method of claim 128 wherein the dose is between about 70 mg/kg and 75 mg/kg body weight.
145 . The method of claim 128 wherein the dose is between about 75 mg/kg and 80 mg/kg body weight.
146 . The method of claim 128 wherein the dose is between about 80 mg/kg and 85 mg/kg body weight.
147 . The method of claim 128 wherein the dose is between about 85 mg/kg and 90 mg/kg body weight.Join the waitlist — get patent alerts
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