US2003139472A1PendingUtilityA1

Use of N-acetylcysteine for the preparation of a medicament suitable for the intravenous administration to prevent oxidative stress in dialysed patients

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Assignee: ZAMBON SPAPriority: Apr 21, 1999Filed: Jan 30, 2003Published: Jul 24, 2003
Est. expiryApr 21, 2019(expired)· nominal 20-yr term from priority
Inventors:Francesco Santangelo
A61P 25/18A61K 31/198A61P 13/12
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Claims

Abstract

The present invention relates to methods of decreasing the effects of oxidative stress in patients undergoing dialysis by intravenously administering N-acetylcysteine or a pharmaceutically acceptable salt thereof to the patient.

Claims

exact text as granted — not AI-modified
1 ) Use of N-acetylcysteine or pharmaceutically acceptable salts thereof for the preparation of a medicament suitable to the intravenous administration to prevent oxidative stress in dialysed patients.  
     
     
         2 ) Use according to  claim 1  wherein N-acetylcysteine is used.  
     
     
         3 ) Use according to  claim 1  wherein the sodium salt of N-acetylcysteine is used.  
     
     
         4 ) Use according to  claim 1  in acute renal disease treatment wherein the dose of N-acetylcysteine or its salts is from 100 to 200 mg/kg.  
     
     
         5 ) Use according to  claim 1  in the chronic treatment wherein the dose of N-acetylcysteine or its salts is from 500 to 5000 mg.

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