US2003125363A1PendingUtilityA1

Riluzole and alpha-tocopherol combination

47
Priority: Nov 13, 1998Filed: Feb 18, 2003Published: Jul 3, 2003
Est. expiryNov 13, 2018(expired)· nominal 20-yr term from priority
Inventors:Michel Dib
A61P 25/00A61P 25/28A61P 21/00A61P 21/02A61K 31/425
47
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Claims

Abstract

The invention concerns a combination of alpha-tocopherol and riluzole or a pharmaceutically acceptable salt thereof and the use of said combination for treating amyotrophic lateral sclerosis.

Claims

exact text as granted — not AI-modified
1 . A method of treating amyotrophic lateral sclerosis or diseases associated with degeneration of the motoneurons comprising administering to a patient in need of said treatment an effective amount of a combination of α-tocopherol and riluzole or of a pharmaceutically acceptable salt thereof, optionally in combination with the pharmaceutically acceptable carrier.  
     
     
         2 . The method according to  claim 1  wherein 10 to 400 parts by weight of riluzole are used per 250 to 4000 parts by weight of α-tocopherol.  
     
     
         3 . The method according to  claim 1  wherein the combination is used simultaneously, separately or spaced out over time.  
     
     
         4 . The method according to  claim 1  wherein the combination is used simultaneously.  
     
     
         5 . The method according to  claim 2  wherein the combination is used simultaneously, separately or spaced out over time.  
     
     
         6 . The method according to  claim 2  wherein the combination is used simultaneously.

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