Multi-capillary electrophoresis apparatus

Abstract

Errors upon analysis caused by, fluctuation in electrophoresis time among plural capillaries in a multi-capillary electrophoresis apparatus is reduced. The multi-capillary electrophoresis apparatus contains a multi-capillary array that has an isolation medium filled therein for isolating a sample, has a sample injecting end on one end thereof, and has, at a position remote from the sample injecting end, a detector part for acquiring information depending on the sample, a voltage applying part for applying a voltage to an electrification path containing the sample injecting end and the detector part, a thermostat oven containing all or a part of the multi-capillary array except for the sample injecting end, a buffer container containing a buffer solution, in which the sample injecting end is immersed, and a temperature controlling part for controlling a temperature of the buffer solution.

What is claimed is:  
     
         1 . A multi-capillary electrophoresis apparatus comprising: 
 a multi-capillary array having an isolation medium filled therein for isolating a sample, a sample injecting end on one end thereof, and a detector part for acquiring information depending on the sample at a position remote from the sample injecting end;    a voltage applying part for applying a voltage to an electrification path comprising the sample injecting end and the detector part;    a thermostat oven containing all or a part of the multi-capillary array except for the sample injecting end;    a buffer container containing a buffer solution, in which the sample injecting end is immersed; and    a temperature controlling part for controlling a temperature of the buffer solution.    
     
     
         2 . A multi-capillary electrophoresis apparatus as claimed in  claim 1 , wherein the temperature controlling part comprises a heater in contact with the buffer container.  
     
     
         3 . A multi-capillary electrophoresis apparatus comprising: 
 a multi-capillary array having an isolation medium filled therein for isolating a sample, a sample injecting end on one end thereof, and a detector part for acquiring information depending on the sample at a position remote from the sample injecting end;    a voltage applying part for applying a voltage to an electrification path comprising the sample injecting end and the detector part;    a thermostat oven containing all or a part of the multi-capillary array except for the detector part; and    a temperature controlling part for controlling a temperature of the detector part.    
     
     
         4 . A multi-capillary electrophoresis apparatus as claimed in  claim 3 , wherein the temperature controlling part comprises a heater arranged in a vicinity of the detector part.  
     
     
         5 . A multi-capillary electrophoresis apparatus comprising: 
 a multi-capillary array having an isolation medium filled therein for isolating a sample, a sample injecting end on one end thereof, and a detector part for acquiring information depending on the sample at a position remote from the sample injecting end;    a voltage applying part for applying a voltage to an electrification path comprising the sample injecting end and the detector part;    a thermostat oven containing all or a part of the multi-capillary array except for the sample injecting end and the detector part;    a buffer container containing a buffer solution, in which the sample injecting end is immersed;    a first temperature controlling part for controlling a temperature of the buffer solution; and    a second temperature controlling part for controlling a temperature of the detector part.    
     
     
         6 . A multi-capillary electrophoresis apparatus as claimed in  claim 5 , 
 wherein the first temperature controlling part comprises a first heater for heating the buffer solution and a first sensor for measuring a temperature of the buffer solution; and    the second temperature controlling part comprises a heater for heating the detector part and a second sensor for measuring a temperature of the detector part.    
     
     
         7 . A multi-capillary electrophoresis apparatus comprising: 
 a multi-capillary array having an isolation medium filled therein for isolating a sample, a sample injecting end on one end thereof, and a detector part for acquiring information depending on the sample at a position remote from the sample injecting end;    a voltage applying part for applying a voltage to an electrification path comprising the sample injecting end and the detector part;    a thermostat oven containing all or a part of the multi-capillary array except for the detector part; and    a temperature controlling part for controlling a temperature in a vicinity of an outlet of the thermostat oven on a side of the detector part.    
     
     
         8 . A multi-capillary electrophoresis apparatus comprising: 
 a multi-capillary array having an isolation medium filled therein for isolating a sample, a sample injecting end on one end thereof, and a detector part for acquiring information depending on the sample at a position remote from the sample injecting end;    a voltage applying part for applying a voltage to an electrification path comprising the sample injecting end and the detector part;    a thermostat oven containing all or a part of the multi-capillary array;    a gel block arranged outside the thermostat oven and charging the isolation medium in the capillary array; and    a temperature controlling part for controlling a temperature of the gel block.    
     
     
         9 . A multi-capillary electrophoresis apparatus comprising: 
 a multi-capillary array having an isolation medium filled therein for isolating a sample, a sample injecting end on one end thereof, and a detector part for acquiring information depending on the sample at a position remote from the sample injecting end;    a voltage applying part for applying a voltage to an electrification path comprising the sample injecting end and the detector part;    a thermostat oven containing all or a part of the multi-capillary array; a flow path connected to the multi-capillary array and having the isolation medium filled therein; and    a temperature controlling part for controlling a temperature of the flow path.    
     
     
         10 . A multi-capillary electrophoresis apparatus comprising: 
 a multi-capillary array having an isolation medium filled therein for isolating a sample, a sample injecting end on one end thereof, and a detector part for acquiring information depending on the sample at a position remote from the sample injecting end;    a voltage applying part for applying a voltage to an electrification path comprising the sample injecting end and the detector part;    a thermostat oven containing all or a part of the multi-capillary array;    a flow path connected to the multi-capillary array and having the isolation medium filled therein;    a buffer container containing a buffer solution, in which the flow path is immersed; and    a temperature controlling part for controlling a temperature of the buffer solution.    
     
     
         11 . A multi-capillary electrophoresis apparatus as claimed in  claim 10 , wherein the temperature controlling part comprises a heater in contact with the buffer container.  
     
     
         12 . A multi-capillary electrophoresis apparatus as claimed in  claim 1 , wherein the detector part comprises a photo accepting unit receiving excitation light generated upon irradiating the sample with laser light, and a Peltier element cooling the photo acceptance unit or heating the detector part.