Microbial production of r-phenylacetycarbinol by biotransformation of benzaldehyde by filamentous fungi

Abstract

Process for the production of R-phenylacetylcarbinol by biotransformation of benzaldehyde by filamentous fungi.

1 . Process for the production of R-phenylacetylcarbinol by biotransformation of benzaldehyde by filamentous fungi  
     
     
         2 . Process according to  claim 1  where the filamentous fungi are selected from the group of Rhizopus, Neurospora, Polyporus, Fusarium, Monilia, Paecilomyces, Mucor.  
     
     
         3 . Process according to  claim 2  where the filamentous fungi are selected from the group of Rhizopus, Fusarium, Mucor.  
     
     
         4 . Process according to  claim 3  where the filamentous fungi are  Rhizopus javanicus  or  Mucor rouxii.    
     
     
         5 . Process according to claim  1 - 4  where the biotransformation of benzaldehyde is made in the presence of pyruvate.  
     
     
         6 . Process according to  claim 5  where 1-2 mol pyruvat are added per mol of benzaldehyde.  
     
     
         7 . Process according to claim  1 - 6  where the biotransformation is made by extracts of filamentous fungi.  
     
     
         8 . Process according to  claim 7  where the extracts contain pyruvate decarboxylase.  
     
     
         9 . Process according to  claim 8  where the pyruvate decarboxylase is stabilised.