Allergy treatment method using a rapid immunotherapy protocol

Abstract

A method of treating a patient sensitive to an allergen includes a desensitizing rapid immunotherapy protocol of administering to the patient a series of gradually increasing doses of a composition comprising the allergen at intervals of about 15 minutes for a duration of less than about 120 minutes, and preferably less than about 90 minutes. A pretreatment protocol administers to the patient a therapeutically effective amount of at least one composition that is effective in reducing a sensitivity of the patient to an asthma associated allergenic reaction.

What is claimed is:  
     
         1 . A method of treating a patient sensitive to an allergen, comprising administering to said patient a therapeutically effective desensitizing amount of a composition comprising said allergen over a duration of less than about 120 minutes.  
     
     
         2 . The method as recited in  claim 1 , wherein the administration of said therapeutically effective desensitizing amount of said allergen composition being conducted according to a rapid immunotherapy protocol.  
     
     
         3 . The method as recited in  claim 1 , further comprises a pretreatment protocol of administering to said patient a therapeutically effective amount of at least one composition effective in reducing a sensitivity of said patient to an asthma associated allergenic reaction.  
     
     
         4 . The method as recited in  claim 1 , further comprises a pretreatment protocol of administering to said patient a corticosteroid and at least one of an H 1  histamine antagonist and an H 2  histamine antagonist.  
     
     
         5 . The method as recited in  claim 4 , wherein said pretreatment protocol further comprising administering to said patient at least one of a corticosteroid and a leukotriene antagonist.  
     
     
         6 . The method as recited in  claim 4 , wherein said pretreatment protocol further comprising administering to said patient a therapeutically effective amount of at least one composition effective in reducing a sensitivity of said patient to an asthma associated allergenic reaction.  
     
     
         7 . The method as recited in  claim 1 , wherein the administration of said allergen amount further comprises administering to said patient at selected intervals gradually increasing doses of said allergen.  
     
     
         8 . The method as recited in  claim 7 , wherein each selected interval being about fifteen minutes.  
     
     
         9 . The method as recited in  claim 1 , wherein the administration of said allergen amount further comprises administering to said patient at intervals of about fifteen minutes gradually increasing doses of said allergen.  
     
     
         10 . The method as recited in  claim 9 , wherein the intervaled administration of allergen occurring in accordance with a dosing schedule consisting essentially of: 
 (i) an amount having about a 1:100,000 allergen dilution,    (ii) an amount having about a 1:100,000 allergen dilution,    (iii) an amount having about a 1:10,000 allergen dilution,    (iv) an amount having about a 1:10,000 allergen dilution,    (v) an amount having about a 1:1000 allergen dilution, and    (vi) an amount having about a 1:1000 allergen dilution.    
     
     
         11 . The method as recited in  claim 9 , wherein each said allergen dosage having a dilution level within the range of from between about 1:150,000 to about 1:50,000 to between about 1:1500 to about 1:500.  
     
     
         12 . The method as recited in  claim 11 , further comprises a pretreatment protocol of administering to said patient a therapeutically effective amount of at least one composition effective in reducing a sensitivity of said patient to an asthma associated allergenic reaction.  
     
     
         13 . The method as recited in  claim 11 , further comprises a pretreatment protocol of administering to said patient prednisone and at least one of an H 1  histamine antagonist and an H 2  histamine antagonist.  
     
     
         14 . The method as recited in  claim 13 , wherein said pretreatment protocol further comprising administering to said patient at least one of a corticosteroid and a leukotriene antagonist.  
     
     
         15 . The method as recited in  claim 13 , wherein said pretreatment protocol further comprising administering to said patient a therapeutically effective amount of at least one composition effective in reducing a sensitivity of said patient to an asthma associated allergenic reaction.  
     
     
         16 . The method as recited in  claim 1 , wherein said administration step being concurrently repeated using another allergen.  
     
     
         17 . The method as recited in  claim 1 , wherein said administering step further includes the step of administering to said patient at intervals of about 15 minutes gradually increasing doses of said allergen each having a dilution level within the range of from between about 1:150,000 to about 1:50,000 to between about 1:1500 to about 1:500.  
     
     
         18 . A method of treating a patient sensitive to an allergen, comprising a protocol of administering to said patient a series of gradually increasing doses of a composition comprising said allergen at selected intervals for a duration of less than about 120 minutes.  
     
     
         19 . The method as recited in  claim 18 , wherein each selected interval being about fifteen minutes.  
     
     
         20 . The method as recited in  claim 19 , wherein the dilution level of allergen within each dosage being within the range from between about 1:150,000 to about 1:50,000 to between about 1:1500 to about 1:500.  
     
     
         21 . The method as recited in  claim 19 , wherein said protocol being defined by a dosing schedule consisting essentially of: 
 (i) an amount having about a 1:100,000 allergen dilution,    (ii) an amount having about a 1:100,000 allergen dilution,    (iii) an amount having about a 1:10,000 allergen dilution,    (iv) an amount having about a 1:10,000 allergen dilution,    (v) an amount having about a 1:1000 allergen dilution, and    (vi) an amount having about a 1:1000 allergen dilution.    
     
     
         22 . The method as recited in  claim 19 , wherein the amount of said composition administered to said patient according to said protocol being therapeutically effective in desensitizing said patient against said allergen.  
     
     
         23 . The method as recited in  claim 19 , wherein said allergen being selected from the group consisting of mold, mildew, dust, and dander.  
     
     
         24 . The method as recited in  claim 19 , wherein said protocol being concurrently repeated using another allergen.  
     
     
         25 . The method as recited in  claim 19 , further comprises a pretreatment protocol of administering to said patient a therapeutically effective amount of at least one composition effective in reducing a sensitivity of said patient to an asthma associated allergenic reaction.  
     
     
         26 . The method as recited in  claim 19 , further comprises a pretreatment protocol of administering to said patient prednisone and at least one of an H 1  histamine antagonist and an H 2  histamine antagonist.  
     
     
         27 . The method as recited in  claim 26 , wherein said prednisone being administered according to a daily dosage of about 60mg/adult and 2mg/kg/child.  
     
     
         28 . The method as recited in  claim 26 , wherein said pretreatment protocol being carried out over about three days.  
     
     
         29 . The method as recited in  claim 26 , wherein said H 1  histamine antagonist being selected from the group consisting of Claritin, Seldane, Zyrtec, and Allegra, and said H 2  histamine antagonist being selected from the group consisting of Zantac, Pepcid, and Tagamet.  
     
     
         30 . The method as recited in  claim 26 , wherein said pretreatment protocol further comprising administering to said patient at least one of a corticosteroid and leukotriene antagonist.  
     
     
         31 . The method as recited in  claim 26 , wherein said pretreatment protocol further comprising administering to said patient a therapeutically effective amount of at least one composition effective in reducing a sensitivity of said patient to an asthma associated allergenic reaction.  
     
     
         32 . A method of treating a patient sensitive to an allergen, comprising a protocol of administering to said patient a series of gradually increasing doses of a composition comprising said allergen at intervals of about 15 minutes for a duration of less than about 120 minutes.  
     
     
         33 . The method as recited in  claim 32 , wherein the dilution level of allergen within each dosage being within the range from between about 1:150,000 to about 1:50,000 to between about 1:1500 to about 1:500.a  
     
     
         34 . The method as recited in  claim 33 , wherein said protocol being defined by a dosing schedule consisting essentially of: 
 (i) an amount having about a 1:100,000 allergen dilution,    (ii) an amount having about a 1:100,000 allergen dilution,    (iii) an amount having about a 1:10,000 allergen dilution,    (iv) an amount having about a 1:10,000 allergen dilution,    (v) an amount having about a 1:1000 allergen dilution, and    (vi) an amount having about a 1:1000 allergen dilution.    
     
     
         35 . The method as recited in  claim 32 , wherein the amount of said composition administered to said patient according to said protocol being therapeutically effective in desensitizing said patient against said allergen.  
     
     
         36 . The method as recited in  claim 32 , further comprises a pretreatment protocol of administering to said patient a therapeutically effective amount of at least one composition effective in reducing a sensitivity of said patient to an asthma associated allergenic reaction.  
     
     
         37 . The method as recited in  claim 32 , further comprises a pretreatment protocol of administering to said patient prednisone and at least one of an H 1  histamine antagonist and an H 2  histamine antagonist.  
     
     
         38 . The method as recited in  claim 37 , wherein said pretreatment protocol further comprising administering to said patient at least one of a corticosteroid and leukotriene antagonist.  
     
     
         39 . The method as recited in  claim 37 , wherein said pretreatment protocol further comprising administering to said patient a therapeutically effective amount of at least one composition effective in reducing a sensitivity of said patient to an asthma associated allergenic reaction.  
     
     
         40 . In the method for the treatment of an allergic condition by means of desensitization therapy by administering to a subject gradually increasing doses of a causative agent, the improvement wherein the administration of said causative agent being conducted at intervals of between about 10 to 20 minutes for a duration of less than about 120 minutes using at each interval a dosage of said causative agent within the range of from between about 1:150,000 to about 1:50,000 to between about 1:1500 to about 1:500.  
     
     
         41 . A method of treating a patient sensitive to an allergen, comprising a protocol of administering to said patient a series of gradually increasing doses of a composition comprising said allergen at selected intervals for a duration of less than about 120 minutes, said protocol being defined by a dosing schedule consisting essentially of: 
 (i) an amount having about a 1:100,000 allergen dilution,    (ii) an amount having about a 1:100,000 allergen dilution,    (iii) an amount having about a 1:10,000 allergen dilution,    (iv) an amount having about a 1:10,000 allergen dilution,    (v) an amount having about a 1:1000 allergen dilution, and    (vi) an amount having about a 1:1000 allergen dilution.    
     
     
         42 . The method as recited in  claim 41 , wherein each selected interval being about fifteen minutes.  
     
     
         43 . The method as recited in  claim 41 , further comprises a pretreatment protocol of administering to said patient prednisone and at least one of an H 1  histamine antagonist and an H 2  histamine antagonist.  
     
     
         44 . The method as recited in  claim 43 , wherein said H 1  histamine antagonist being selected from the group consisting of Claritin, Seldane, Zyrtec, and Allegra, and said H 2  histamine antagonist being selected from the group consisting of Zantac, Pepcid, and Tagamet.  
     
     
         45 . The method as recited in  claim 43 , wherein said pretreatment protocol further comprising administering to said patient at least one of a corticosteroid and leukotriene antagonist.  
     
     
         46 . A method of pretreating a patient prior to receiving desensitizing rapid immunotherapy, comprising the steps of: 
 administering to said patient prednisone and at least one of an H 1  histamine antagonist and an H 2  histamine antagonist; and    administering to said patient a therapeutically effective amount of at least one composition effective in reducing the sensitivity of said patient to an asthma associated allergenic reaction occurrable during and/or after reception of the desensitizing rapid immunotherapy.    
     
     
         47 . The method as recited in  claim 46 , wherein said at least one composition administered to reduce the sensitivity of said patient to an asthma associated allergenic reaction comprising at least one of a corticosteroid and leukotriene antagonist.  
     
     
         48 . A method of pretreating a patient prior to receiving desensitizing rapid immunotherapy, comprising the steps of: 
 administering to said patient prednisone and at least one of an H 1  histamine antagonist and an H 2  histamine antagonist; and    administering to said patient at least one of a corticosteroid and leukotriene antagonist.