US2003069309A1PendingUtilityA1

6-Methoxy-2-naphthylacetic acid prodrugs

59
Priority: Oct 27, 1999Filed: Jun 12, 2002Published: Apr 10, 2003
Est. expiryOct 27, 2019(expired)· nominal 20-yr term from priority
Inventors:Nnochiri EkwuribeTatyana Dyakonov
A61K 31/21A61K 31/16A61K 31/216A61P 29/00A61K 31/167A61K 31/235A61K 31/085A61K 31/265A61K 31/215
59
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Claims

Abstract

The present invention provides therapeutically effective amounts of 6MNA prodrugs. The pharmaceutical composition comprises wherein R is H or COR′, wherein R′ is selected from the group consisting of C 1 to C 6 alkyl, (CH 2 ) m O(CH 2 ) n , (CH 2 ) m (OC 2 H 4 ) p O(CH 2 ) n , (CH 2 ) m (OC 2 H 4 ) p , (OCH 2 H 4 ) p ONO 2 and (OCH 2 H 4 ) p O(CH 2 ) n wherein m is an integer from 2 to 4, and n and p are integers from 1 to 4. Alternatively, R is a therapeutic moiety.

Claims

exact text as granted — not AI-modified
That which is claimed is:  
     
         1 . A pharmaceutical composition useful for treatment of inflammation to humans comprising a therapeutically effective amount of a compound of the formula:  
       
         
           
           
               
               
           
         
       
       wherein R is a therapeutic moiety.  
     
     
         2 . A method of treating inflammation comprising administering a therapeutically effective amount of a compound of the formula:  
       
         
           
           
               
               
           
         
       
       wherein R is a therapeutic moiety.

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