IBDV strain for in ovo administration

Abstract

The present invention provides a novel infectious bursal disease virus, strain 689 which is suited as vaccine candidate for in ovo vaccination and is deposited at the European Collection of Cell Cultures, Salisbury, Wiltshine, United Kingdom under No. V00012609.

1 . A virus of an infectious bursal disease virus strain, a sample of which is deposited at the European Collection of Cell Cultures, Salisbury, Wiltshine, SP4 OJG, United Kingdom under accession No. V00012609.  
     
     
         2 . A virus according to  claim 1 , characterised in that the virus is in a live form.  
     
     
         3 . A vaccine against infectious busal disease, characterised in that it comprises a virus according to claims  1  or  2  and a pharmaceutically acceptable carrier or a diluent.  
     
     
         4 . A vaccine according to  claim 3 , characterised in that the vaccine comprises an effective dose per egg of 10 1 -10 6  TCID 50 , (Tissue Culture Infectious Dose 50) preferably 10 2 -10 5  TCID 50 .  
     
     
         5 . A vaccine according to  claim 3  or  4 , characterised in that the vaccine additionally comprises an embryo-safe vaccine strain of another avian pathogen.  
     
     
         6 . A method for the preparation of the virus according to  claim 1  or  2 , characterised in that the virus is cultured on a suitable substrate and harvested from the substrate.  
     
     
         7 . A method for preparation of the vaccine according to claim  3 - 5 , characterised in that a virus according to  claim 1  or  2  is mixed with a pharmaceutical suitable carrier or a diluent.  
     
     
         8 . Use of the virus according to  claim 1  or  2  for the manufacture of a vaccine for the protection of birds against infectious bursal disease for in ovo administration.