Methods of treatment comprising administration of Substance P

Abstract

A method for treatment of symptoms of a respiratory disease or pain in a subject comprising administering to said subject a Substance P in an amount effective to alleviate those symptoms.

What is claimed:  
     
         1 . A method for the treatment of symptoms of a respiratory disease or pain in a subject comprising administering to said subject a Substance P in an amount effective to alleviate those symptoms.  
     
     
         2 . The method of  claim 1  wherein said respiratory disease is Reactive Upper Airway Dysfunction.  
     
     
         3 . The method of  claim 1  wherein the disease is neurogenic pain.  
     
     
         4 . The method of  claim 1  wherein the disease is peripheral neuropathy.  
     
     
         5 . The method of  claim 1  wherein Substance P is administered by a route selected from the group consisting of sublingual administration and subcutaneous administration.  
     
     
         6 . The method of  claim 5  wherein Substance P is administered by sublingual administration.  
     
     
         7 . The method of  claim 6  wherein Substance P is administered at a dosage of from 10 −5  to 10 −4  mg one to six times daily.  
     
     
         8 . A pharmaceutical composition for treatment of symptoms of a respiratory disease or pain in a subject comprising Substance P in an amount effective to alleviate those symptoms and a suitable carrier.  
     
     
         9 . The pharmaceutical composition of  claim 8  wherein the Substance P is present in a dosage of from 10 −5  to 10 −4  mg.