Foam skin cream, uses of the foam skin protection cream and a process for its preparation

Abstract

A foam skin cream can be obtained by preparing a phase I by melting at 75° C. a mixture containing fatty acids, especially C 12 -C 22 fatty acids, optionally unsaturated and/or polyunsaturated fatty acids, emulsifiers, coemulsifiers, such as triceteareth-4-phosphate, followed by metering it with stirring to a phase II temperature-controlled at 75° C. obtained from an aqueous mixture containing moisturizers, such as propylene glycol and/or polyhydric alcohols, especially glycerol, emulsifiers, such as alkyl sarcosinates, and skin care additives, such as allantoin; wherein homogeneous mixing of phases I and II is provided and said metering is performed at a temperature of 75° C.; after the metered addition, the temperature is maintained at 75° C. for a period of between 5 and 20 minutes; whereupon the temperature of the thus obtained mixture is lowered to a temperature of between 30 and 40° C. with constant stirring; the pH value is adjusted to from 7.6 to 8.2, preferably with a skin-compatible basic organic compound, and the mixture obtained is filled into dosage forms with the addition of a propellant.

1 . A foam skin cream, obtainable by 
 preparing a phase I by melting at 75° C. a mixture containing fatty acids, especially C 10 -C 22  fatty acids, optionally unsaturated and/or polyunsaturated fatty acids, emulsifiers, coemulsifiers, such as triceteareth-4-phosphate, followed by metering it with stirring to    a phase II temperature-controlled at 75° C. obtained from an aqueous mixture containing moisturizers, such as propylene glycol and/or polyhydric alcohols, especially glycerol, emulsifiers, such as alkyl sarcosinates, and skin care additives, such as allantoin;    wherein homogeneous mixing of phases I and II is provided and said metering is performed at a temperature of 75° C.;    after the metered addition, the temperature is maintained at 75° C. for a period of between 5 and 20 minutes; whereupon    the temperature of the thus obtained mixture is lowered to a temperature of between 30 and 40° C. with constant stirring;    the pH value is adjusted to from 7.6 to 8.2, preferably with a skin-compatible basic organic compound, and the mixture obtained is filled into dosage forms with the addition of a propellant.    
     
     
         2 . The foam skin cream according to  claim 1 , wherein a preservative is added to the mixture of phases I and II with stirring at 30 to 40° C.  
     
     
         3 . The foam skin cream according to  claim 1  or  2 , containing 
 from 4 to 15% by weight of oil-in-water emulsifier;  
 from 1 to 10% by weight of fatty acid;  
 from 0.4 to 2.3% by weight of coemulsifier;  
 from 1 to 10% by weight of moisturizer;  
 from 0.05 to 1% by weight of skin care agent; and  
 water as the balance to make 100% by weight.  
 
     
     
         4 . The foam skin cream according to any of  claims 1  to  3 , containing 
 from 1 to 3% by weight of glyceryl stearate;  
 from 3 to 6% by weight of cetearyl alcohol;  
 from 4 to 6% by weight of stearic acid;  
 from 0.5 to 2% by weight of paraffin;  
 from 0.4 to 2.3% by weight of triceteareth-4-phosphate;  
 from 1.5 to 4% by weight of propylene glycol;  
 from 1.3 to 4.2% by weight of glycerol;  
 from 1 to 3% by weight of cetyl sarcosinate;  
 from 0.05 to 1% by weight of allantoin; and  
 water as the balance to make 100% by weight.  
 
     
     
         5 . The foam skin cream according to any of  claims 1  to  4 , additionally containing a silicone-containing compound, such as dimethicone, in phase I, preferably in amounts of from 0.05 to 1% by weight.  
     
     
         6 . The foam skin cream according to any of  claims 1  to  5 , additionally containing one or more refatting substances in phase I, such as decyl oleate, isohexadecane, stearic acid glycol ester, coconut fatty acid ethanolamide, corn oil, peanut oil, almond oil, sesame oil, olive oil, jojoba oil, soybean oil, wool wax alcohols, paraffin, medium-chain triglycerides, oleic acid oleyl esters, white petrolatum, macrogol-glycerol hydroxystearate, hydrogenated castor oil, castor oil from  Ricinus communis,  avocado oil, wheat germ oil, palmitic acid isopropyl ester, cetyl palmitate, myristic acid myristyl ester and/or octyidodecanol.  
     
     
         7 . The foam skin cream according to  claim 6 , containing 
 from 0.5 to 2% by weight of decyl oleate; and/or    from 0.5 to 2% by weight of octyldecanol.    
     
     
         8 . The foam skin cream according to  claim 6 , containing 
 from 3 to 6% by weight of decyl oleate; and/or    from 3 to 6% by weight of octyidecanol.    
     
     
         9 . The foam skin cream according to  claim 6 , containing 
 from 6 to 9% by weight of decyl oleate; and/or    from 6 to 9% by weight of octyldecanol.    
     
     
         10 . The foam skin cream according to any of  claims 1  to  9 , additionally containing hydratizing (moisture-binding) agents in phase II, such as urea, ethoxydiglycol, sodium chloride, magnesium chloride, sorbitol, dexpanthenol, sodium lactate, preferably from 1 to 20% by weight of urea.  
     
     
         11 . The foam skin cream according to any of  claims 1  to  10 , containing polyunsaturated fatty acids, such as ω-6 fatty acids, soothing substances, such as chamomile extract, and/or skin-active vitamins.  
     
     
         12 . The foam skin cream according to any of  claims 6  to  10 , containing 
 from 3 to 7% by weight of Calendula extract;  
 from 3 to 7% by weight of Hamamelis extract;  
 from 3 to 7% by weight of chamomile extract;  
 from 3 to 7% by weight of tea tree oil extract;  
 from 1 to 5% by weight of decyl oleate;  
 from 1 to 5% by weight of octyldodecanol.  
 
     
     
         13 . Use of the foam skin cream according to any of  claims 1  to  12  for the protection from or reduction of the absorption of cancerogenic substances, such as polycyclic aromatic hydrocarbons, for persons exposed to such substances, acids, lyes (not above pH 11), scouring agents and detergents, sweat, urine, stool, rubber gloves, dusts, house dust, machine, drilling and cooling oils, greases, paints/varnishes, gypsum and other substances and chemicals, especially aggressive substances and chemicals.  
     
     
         14 . Use of the foam skin cream according to any of  claims 6  to  11  for the alleviation of dermatological diseases, such as allergic contact dermatitis type I and IV, cumulative-subtoxic eczema, toxic-irritative eczema, microbial-dysregulative eczema, atopic dermatitis, atopic palmoplantar eczema, dyshidrosis, hyperhidrosis, contact urticaria, intertriginous eczema in connection with hemorrhoids, various weeping fungal infections, e.g., interdigital mycosis, perlèches, psoriasis vulgaris, ulcus cruris, cholinergic urticaria, diaper dermatitis.  
     
     
         15 . Use of the foam skin cream according to  claim 10  for the prophylaxis and therapy of diabetic foot.  
     
     
         16 . Use of the foam skin cream according to  claim 12  for the treatment and prevention of diaper dermatitis.  
     
     
         17 . A process for the preparation of a foam skin cream according to at least one of  claims 1  to  12 , comprising: 
 preparing a phase I by melting at 75° C. a mixture containing fatty acids, especially C 12 -C 22  fatty acids, optionally unsaturated and/or polyunsaturated fatty acids, coemulsifiers, such as triceteareth-4-phosphate, followed by metering this phase with stirring to  
 a phase II molten at 75° C. obtained from an aqueous mixture containing moisturizers, such as propylene glycol and/or polyhydric alcohols, especially glycerol, emulsifiers, such as alkyl sarcosinates, and skin care additives, such as allantoin;  
 wherein homogeneous mixing of phases I and II is provided and said metering is performed at a temperature of 75° C.;  
 after the addition of phase I to phase II, the temperature is maintained at 75° C. for a period of between 5 and 20 minutes; whereupon 
 the temperature of the thus obtained mixture is lowered to a temperature of between 30 and 40° C. with constant stirring;  
 adjusting the pH value to from 7.6 to 8.2, preferably with a skin-compatible basic organic compound, and filling into containers with the addition of a propellant.