US2003022365A1PendingUtilityA1

Arrangement for treating cells in biology or genetic engineering

Priority: Sep 24, 1998Filed: Sep 23, 2002Published: Jan 30, 2003
Est. expirySep 24, 2018(expired)· nominal 20-yr term from priority
Inventors:Stefan Marotzki
C12M 23/38C12M 23/10C12M 25/02C12M 23/46
36
PatentIndex Score
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Claims

Abstract

A device for receiving a liquid containing a cell culture includes at least one vessel having a base plate and walls forming an enclosure. A cover is lowerable into the vessel to displace air and, where appropriate, excess liquid. The cover has a liquid admission opening and a liquid discharge opening.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . A device for receiving a liquid containing a cell culture comprising: 
 a vessel having a base plate and a wall structure defining an enclosure; and    a cover lowerable into the vessel to displace air and, where appropriate, excess liquid, said cover having a liquid admission opening and a liquid discharge opening.    
     
     
         2 . The device according to  claim 1  further comprising one or more walls for defining a plurality of separate chambers inside the vessel.  
     
     
         3 . The device according to  claim 2 , wherein said vessel has a first width and further comprising a second vessel having a second width which is less than said first width, said second vessel being disposed in said first vessel.  
     
     
         4 . The device according to  claim 3 , wherein said cover closes only the portion of the wider first vessel which is situated outside of the second vessel.  
     
     
         5 . The device according to  claim 3 , wherein the cover defines a cutout which is configured to be complementary with the circumference of the second vessel.  
     
     
         6 . The device according to  claim 5 , wherein the cutout is defined by an opening of the cover.  
     
     
         7 . The device according to  claim 3 , wherein the cover is a holder for the second vessel.  
     
     
         8 . The device according to  claim 7 , wherein the cover connects with the second vessel to permit joint handling.  
     
     
         9 . The device according to  claim 3  further comprising a separate cover for covering the second vessel.  
     
     
         10 . The device according to  claim 2  further comprising a ring enclosing a separate chamber disposed between the base plate and a base of the cover and the cover has an opening communicating with the chamber.  
     
     
         11 . The device according to  claim 1 , further comprising at least one cell culture insert.  
     
     
         12 . The device according to  claim 1 , wherein at least one of the openings is provided with a screen.  
     
     
         13 . The device according to  claim 1 , wherein the cover has an upper side defining a trough in fluid communication with at least one of the openings.  
     
     
         14 . The device according to  claim 13 , wherein the trough has a lower base which is not disposed lower than a mouth of the associated opening.  
     
     
         15 . The device according to  claim 14 , wherein the upper side of the cover defines first and second troughs associated with the liquid admission opening and liquid discharge opening, respectively, the first trough being separated from the second trough.  
     
     
         16 . The device according to  claim 13 , wherein a plurality of vessels are enclosed by the cover, the trough being in fluid communication with each of the vessels through a one of the openings disposed proximate to the vessel.  
     
     
         17 . The device according to  claim 1 , wherein the cover has a plurality of openings, at least one of the openings being a liquid admission opening and at least one of the openings being a liquid discharge opening.  
     
     
         18 . The device according to  claim 1 , wherein the device comprises a plurality of contiguous vessels.  
     
     
         19 . The device according to  claim 4 , wherein the cover defines a cutout which is configured to be complementary with the circumference of the second vessel.  
     
     
         20 . The device according to  claim 4 , further comprising a separate cover for covering the second vessel.  
     
     
         21 . An arrangement for biological treatment or genetic engineering of cells comprising: 
 at least one vessel each having a base plate and a wall defining an enclosure for receiving cells and a treatment liquid;    a machine having means for exchanging the liquid; and    a cover having at least first and second openings;    wherein the liquid exchange means introduces liquid into the first opening and removes it from the second opening.    
     
     
         22 . The arrangement of  claim 21 , wherein said cover has an upper side defining first and second troughs in fluid communication with the first and second openings, respectively, and the liquid exchange means introduces liquid into the first trough and removes it from the second trough.

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