US2003017165A1PendingUtilityA1

Chemically programmable immunity

Priority: Dec 22, 1999Filed: Jun 21, 2002Published: Jan 23, 2003
Est. expiryDec 22, 2019(expired)· nominal 20-yr term from priority
Inventors:Kary B. Mullis
A61P 37/04A61K 2039/6025A61K 39/385Y02A50/30
54
PatentIndex Score
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Cited by
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Claims

Abstract

The present invention is related to methods and compositions that are capable of immediately immunizing a human or animal against any molecule or compound. The present invention comprises an immunity linker molecule with at least two sites; (1) a first binding site that binds to an immune system molecule in a human or animal that has been preimmunized against the first binding site, and (2) one or more second binding sites that bind specifically to a desired compound or molecule. The first binding site and the second binding site(s) are linked by a linker portion of the molecule.

Claims

exact text as granted — not AI-modified
1 . An immunity linker molecule, the immunity linker molecule containing at least one first site that binds to an immune system molecule and at lease one second site that binds to a desired compound or molecule.  
     
     
         2 . The immunity linker molecule of  claim 1  wherein the first site binds to an antibody.  
     
     
         3 . The antibody of  claim 2  wherein the antibody is from a human or animal that has been preimmunized against the first site.  
     
     
         4 . The immunity linker molecule of  claim 1 , wherein the desired compound or molecule is a microorganism.  
     
     
         5 . The immunity linker molecule of  claim 4  wherein the microorganism is a bacteria, virus, or fungus.  
     
     
         6 . The immunity linker molecule of  claim 1 , wherein the compound or molecule is a drug.  
     
     
         7 . The immunity linker molecule of  claim 1 , wherein the immunity linker molecule is an aptomer.  
     
     
         8 . A method of immunizing a human or animal against a molecule or compound comprising administering to the human or animal an immunity linker molecule, the immunity linker molecule containing at least one first site second site that binds to a desired compound or molecule.  
     
     
         9 . The method of  claim 8 , wherein the human or animal has been preimmunized against the first site on the immunity linker molecule.  
     
     
         10 . The method of  claim 8 , wherein the immunity the desired compound or molecule is a microorganism.  
     
     
         11 . The method of  claim 10  wherein the microorganism is a bacteria, virus, or fungus.  
     
     
         12 . The method of  claim 8 , wherein the compound or molecule is a drug.  
     
     
         13 . The method of  claim 1 , wherein the immunity linker molecule is an aptomer.  
     
     
         14 . A method of preimmunizing a human or animal comprising immunizing a human or animal against a molecule that contains a first site that is immunogenic, the first site being present on an immune linker molecule, the immune linker molecule also containing at lease one second site that binds to a desired compound or molecule.

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