Collagen fabrics

Abstract

A collagen fiber and methods for producing and using the collagen fiber of the inventions to prepare hemostatic fabrics to control bleeding are provided. The collagen particles (e.g., fibrils) of the fiber, preferably, have a hemostatic activity that is equivalent to the hemostatic activity of the collagen particles from which the fiber is formed. The collagen fibers of the invention and hemostatic fabrics formed thereof optionally include hemostatic agents and/or other therapeutic agents, to further promote hemostasis and wound healing.

What is claimed:  
     
         1 . A hemostatic fabric comprising collagen fibrils, wherein the fibrils have not been subjected to acid dissolution  
     
     
         2 . The fiber of  claim 1 , wherein the collagen fibrils comprise microfibrillar collagen fibrils.  
     
     
         3 . The fiber of  claim 1 , wherein the collagen fibrils comprise a collagen flour.  
     
     
         4 . The fiber of  claim 1 , wherein the collagen fibrils have a bulk density in the range of from about 1.5 to about 3.5 lbs/ft 3 .  
     
     
         5 . The fiber of  claim 1 , further comprising a hemostatic agent.  
     
     
         6 . A fabric formed of a plurality of collagen fibers of  claim 1 .  
     
     
         7 . A sterile package containing a fabric according to  claim 6 .  
     
     
         8 . A collagen fiber formed of collagen fibrils, wherein the collagen fibrils are not denatured.  
     
     
         9 . The fiber of  claim 8 , wherein the collagen fibrils comprise microfibrillar collagen fibrils.  
     
     
         10 . The fiber of  claim 8 , wherein the collagen fibrils comprise a collagen flour.  
     
     
         11 . The fiber of  claim 8 , wherein the collagen fibrils have a bulk density in the range of from about 1.5 to about 3.5 lbs/ft 3 .  
     
     
         12 . The fiber of  claim 8 , further comprising a hemostatic agent.  
     
     
         13 . A fabric formed of a plurality of collagen fibers of  claim 8 .  
     
     
         14 . A sterile package containing a fabric according to claim  13 .