Migraine medicine and method of treating the same without caffeine

Abstract

This invention is a safe and effective composition and method for treating acute migraine attacks using pseudoephedrine, acetaminophen, and other agents in an orally administrated form to alleviate the pain and cluster of symptoms characteristic of migraine attacks such as nausea, photophobia, phonophobia, and functional disabilities as well as the prodrome phase of a migraine attack.

We claim:  
     
         2 . A method for treating migraine pain and the cluster of symptoms characteristic of a migraine attack, the symptoms include nausea, photophobia, phonophobia, and/or functional disability, comprising the steps of administering to a human subject a composition comprising a combination of pseudoephedrine and acetaminophen in an amount effective to reduce or eliminate the migraine pain and one or more of said symptoms characteristic of migraine.  
     
     
         4 . The method according to  claim 2 , wherein two or more of said symptoms characteristic of migraine are reduced.  
     
     
         6 . The method according to  claim 2 , wherein said composition is administered in a solid oral dosage form.  
     
     
         8 . The method according to  claim 6 , wherein said dosage form is selected from the group consisting of tablets, pills, caplets, and capsules.  
     
     
         10 . The method according to  claim 2 , wherein the amount of composition administered is effective to reduce the migraine pain and/or two or more of said symptoms characteristic of migraine.  
     
     
         12 . The method according to  claim 2 , wherein the amount of composition administered is effective to reduce the migraine pain and/or three or more of said symptoms characteristic of migraine.  
     
     
         14 . The method according to  claim 2 , wherein the amount of composition administered is effective to reduce the migraine pain and/or all four of said symptoms characteristic of migraine.  
     
     
         16 . A method of aborting a migraine attack, wherein the migraine attack is characterized by symptoms including nausea, photophobia, phonophobia, and/or functional disability, comprising the steps of administering to a human subject during a prodrome phase of the migraine attack a migraine abortive effective amount of a composition comprising a combination of pseudoephedrine and acetaminophen.  
     
     
         18 . A method for treating migraine pain and nausea characteristic of a migraine attack comprising the steps of administering to a human subject a composition comprising a combination of pseudoephedrine and acetaminophen in an amount effective to reduce the migraine pain and nausea characteristic of a migraine attack.  
     
     
         20 . A method for treating migraine pain and photophobia characteristic of a migraine attack comprising the steps of administering to a human subject a composition comprising a combination of pseudoephedrine and acetaminophen in an amount effective to reduce the migraine pain and photophobia characteristic of a migraine attack.  
     
     
         22 . A method for treating migraine pain and phonophobia characteristic of a migraine attack comprising the steps of administering to a human subject a composition comprising a combination of pseudoephedrine and acetaminophen in an amount effective to reduce the migraine pain and phonophobia characteristic of a migraine attack.  
     
     
         24 . A method for treating migraine pain and functional disability characteristic of a migraine attack comprising the steps of administering to a human subject a composition comprising a combination of pseudoephedrine and acetaminophen in an amount effective to reduce the migraine pain and functional disability characteristic of migraine attack.  
     
     
         26 . An oral composition according to treat migraine pain and other associated symptoms comprising a medicament component consisting of pseudoephedrine, acetaminophen, and one or more pharmaceutically acceptable additives selected from the group consisting of a glidant, a lubricant, a disintegrating agent, a filler, and a pigmenting material.  
     
     
         28 . The method according to  claim 6 , wherein one solid dosage form comprises pseudoephedrine in an amount of from about 30 mg to about 60 mg, and acetaminophen in an amount of from about 200 mg to about 1000 mg.  
     
     
         31 . The method according to  claim 28 , wherein two solid dosage forms are administered to the human subject about every four to six hours.  
     
     
         34 . The method according to  claim 2 , wherein said composition is administered in a liquid oral dosage form.  
     
     
         36 . The method according to claim  34 , wherein said dosage form is selected from the group consisting of tablets, pills, caplets, capsules, and elixirs.  
     
     
         38 . The method according to claim  34 , wherein one liquid dosage form comprises pseudoephedrine in an amount of from about 30 mg to about 60 mg, and acetaminophen in an amount of from about 200 mg to about 1000 mg.  
     
     
         41 . The method according to claim  34 , wherein two liquid dosage forms are administered to the human subject about every four to six hours.  
     
     
         42 . The method according to claim  34 , wherein the composition is not re-administered to the human subject more frequently than once every six hours.