US2002081639A1PendingUtilityA1

Master molecular rheostat switch for cell signaling

34
Priority: Mar 26, 1999Filed: Jun 12, 2001Published: Jun 27, 2002
Est. expiryMar 26, 2019(expired)· nominal 20-yr term from priority
Inventors:Ann Rearden
G01N 33/57515
34
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

Methods of detecting cell signaling disorders associated with PINCH and ILK, including cell proliferative disorders such as breast cancer are disclosed. Methods of treating and diagnosing disease and disorders associated with PINCH and ILK cell signaling are also disclosed.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . A method for identifying a compound which modulates cell proliferation, comprising contacting a sample containing PINCH polypeptide with a compound suspected of having PINCH modulating activity and detecting an effect on cell proliferation.  
     
     
         2 . The method of  claim 1 , wherein the compound is a peptide.  
     
     
         3 . The method of  claim 1 , wherein the compound is a peptidomimetic.  
     
     
         4 . The method of  claim 1 , wherein the sample comprising PINCH is expressed in a cell.  
     
     
         5 . The method of  claim 1 , wherein the compound is an antibody.

Join the waitlist — get patent alerts

Track US2002081639A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.