US2002072632A1PendingUtilityA1
Catalyst ligands, catalytic metal complexes and processes using same
Est. expiryOct 8, 2018(expired)· nominal 20-yr term from priority
B01J 31/2243B01J 31/24C07C 217/84B01J 2531/847B01J 31/1658C07C 217/92C08F 10/00C07F 15/045B01J 2231/10
47
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Claims
Abstract
New ligands having a backbone comprised of NCCX can be combined with a metal or metal precursor compound or formed into a metal-ligand complex to catalyze a number of different chemical transformations, including polymerization.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A compound characterized by the general formula:
wherein each R 1 , R 2 and R 3 is independently selected from the group consisting of hydrogen, halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, R 1 and R 2 are joined together in a ring structure;
Q 1 and Q 2 are, independently, selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, Q 1 and Q are joined together in a ring structure;
X is selected from the group consisting of oxygen, nitrogen, sulfur and phosphorus; and a is 1 or 2 depending on X.
2 . The compound of claim 1 , wherein each of R 1 and R 2 is independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, heteroalkyl, cycloalkyl, substituted cycloalkyl, aryl and substituted aryl.
3 . The compound of claim 1 , wherein R 1 and R 2 are joined in a ring, wherein the said ring has between 5 and 10 non-hydrogen atoms.
4 . The compound of claim 3 , wherein said ring has between 5 and 6 non-hydrogen atoms in the backbone of the ring.
5 . The compound of claim 1 , wherein R 1 is a substituted or unsubstitued phenyl.
6 . The compound of claim 5 , wherein R 1 is a substituted phenyl and there are from 1-5 substituents on said phenyl ring, with each of said substituents independently selected from the group consisting of halide, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof.
7 . The compound of claim 6 , wherein there are 1, 2 or 3 substituents on said substituted phenyl and said substituents are selected from the group consisting of chloro, fluoro, iodo, bromo, methyl, ethyl, propyl, butyl, pentyl, hexyl, cyclopropyl, cyclobutyl, cyclopentyl, cylcohexyl, cyclooctyl, phenyl, naphthyl, benzyl, trimethylsilyl and isomers thereof, where applicable.
8 . The compound of claim 1 , wherein X is oxygen, a is 1 and R 3 is selected from the group consisting of alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl and silyl.
9 . The compound of claim 8 , wherein R 3 is a substituted phenyl and there are from 1-5 substituents on said phenyl ring, with each of said substituents independently selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof.
10 . The compound of claim 9 , wherein there are 1, 2 or 3 substituents on said substituted phenyl and said substituents are selected from the group consisting of chloro, fluoro, iodo, bromo, methyl, ethyl, propyl, butyl, pentyl, hexyl, cyclopropyl, cyclobutyl, cyclopentyl, cylcohexyl, cyclooctyl, phenyl, naphthyl, benzyl, trimethylsilyl and isomers thereof where applicable.
11 . The compound of claim 1 , wherein Q 1 and Q 2 are joined together in a ring structure with the backbone of the compound, such that the compound can be characterized by the general formula:
wherein R 1 , R 2 , R 3 , X and a each have the definition given above; R 4 is selected from the group consisting of electron withdrawing and electron donating groups; and b is 0, 1, 2, 3 or 4.
12 . The compound of claim 11 , wherein R 4 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, silyl, amino, alkoxy, aryloxy, phosphino, boryl, transition metals, halogens and combinations thereof.
13 . The compound of claim 12 , wherein b is 1, 2 or 3 and R 4 is selected from the group consisting of methyl, ethyl, propyl, butyl, pentyl, phenyl, cyano, acetyl, benzoyl, nitro, dimethylamino, diethylamino, methylphenylamino, benzylmethylamino, trimethylsilyl, dimethylboryl, diphenylboryl, methylphenylboryl, dimethoxyboryl, chromium tricarbonyl, ruthenium tricarbonyl, cyclopentadienyl iron and isomers thereof where applicable.
14 . The compound of claim 11 , wherein two or more R 4 groups combine to form a fused ring structure with the aromatic group that forms a part of the ligand backbone.
15 . The compound of claim 14 , wherein the aromatic group that is part of the backbone as combined with two or more R 4 groups that have formed a fused ring are substituted or unsubstituted naphthalene, substituted or unsubstituted quinoline or substituted or unsubstituted indole.
16 . The compound of claim 11 , wherein R 1 is a substituted or unsubstituted phenyl such that the compound can be characterized by the general formula:
wherein R 2 , R 3 , R 4 , X, a and b each have the definition given above, R 5 is selected from the group consisting of electron withdrawing and electron donating groups; and c is 0, 1, 2, 3, 4 or 5.
17 . The compound of claims 16 , wherein R 5 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, silyl, amino, alkoxy, aryloxy, phosphino, boryl, transition metals, halogens and combinations thereof.
18 . The compound of claim 17 , wherein there are two R 5 groups that are joined in a fused ring structure with the phenyl ring.
19 . The compound of claim 18 , wherein there are four R 5 groups that are joined in a fused ring structure with the phenyl ring.
20 . A complex characterized by one of the following general formulas:
wherein each R 1 , R 2 and R 3 is independently selected from the group consisting of hydrogen, halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, R 1 and R 2 are joined together in a ring structure;
Q 1 and Q 2 are, independently, selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, Q 1 and Q are joined together in a ring structure;
X is selected from the group consisting of oxygen, nitrogen, sulfur and phosphorus; a is 0, 1 or 2 depending on X and the type of bonding to M;
M is a transition metal selected from the group consisting of Groups 4, 5, 6, 7, 8, 9, 10, 11 and 12 of the Periodic Table of Elements;
L is independently each occurrence, a ligand;
n is a number 0, 1, 2, 3, 4, and 5; and
m is 1, 2, 3 or 4.
21 . The complex of claim 20 , wherein M is selected from the group consisting of Sc, Y, Zr, Ti, Hf, V, Nb, Ta, Zn, Mo, Mn, W, Fe, Ru, Os, Co, Rh, Ni, and Pd.
22 . The complex of claim 21 , wherein M is selected from the group consisting of Pd, Ni, Co, Fe, Ru, Rh, Cr, Mo, Mn, and V.
23 . The complex of claim 20 , wherein L is selected from the group consisting of hydrogen, halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, cyclopentadienyl, substituted cyclopentadienyl, imido, oxo and combinations thereof.
24 . The complex of claim 20 , wherein L is selected from the group consisting of alkene, diene, carbon monoxide, isocyanide, nitrous oxide, PA 3 , NA 3 , OA 2 , SA 2 , SeA 2 , and combinations thereof, wherein each A is independently selected from a group consisting of alkyl, substituted alkyl, heteroalkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, and amino.
25 . The complex of claim 20 , wherein R 1 is a substituted or unsubstitued phenyl.
26 . The complex of claim 25 , wherein R 1 is a substituted phenyl and there are from 1-5 substituents on said phenyl ring, with each of said substituents independently selected from the group consisting of halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof.
27 . The complex of claim 26 , wherein there are 1, 2 or 3 substituents on said substituted phenyl and said substituents are selected from the group consisting of chloro, fluoro, iodo, bromo, methyl, ethyl, propyl, butyl, cyclopentyl, cyclohexyl, cyclooctyl, phenyl, naphthyl, benzyl, trimethylsilyl and isomers thereof.
28 . The complex of claim 20 , wherein X is oxygen, a is I and R 3 is selected from the group consisting of alkyl, substituted alkyl, aryl, substituted aryl or silyl.
29 . The complex of claim 28 , wherein R 3 is a substituted phenyl and there are from 1-5 substituents on said phenyl ring, with each of said substituents independently selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof.
30 . The complex of claim 20 , wherein Q 1 and Q 2 are joined together in a ring structure with the backbone of the compound, such that the compound can be characterized by one of the following general formulas:
wherein R 1 , R 2 , R 3 , X, M, L, n, m and a each have the definition given above; R 4 is selected from the group consisting of electron withdrawing and electron donating groups; and b is 0, 1, 2, 3 or 4.
31 . The complex of claim 30 , wherein R 4 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, silyl, amino, alkoxy, aryloxy, phosphino, boryl, transition metals, halogens and combinations thereof.
32 . The complex of claim 31 , wherein b is 1, 2 or 3 and R 4 is selected from the group consisting of methyl, ethyl, propyl, butyl, pentyl, phenyl, cyano, acetyl, benzoyl, nitro, dimethylamino, diethylamino, methylphenylamino, benzylmethylamino, trimethylsilyl, dimethylboryl, diphenylboryl, methylphenylboryl, dimethoxyboryl, chromium tricarbonyl, ruthenium tricarbonyl, cyclopentadienyl iron and isomers thereof where applicable.
33 . The complex of claim 32 , wherein two or more R 4 groups combine to form a fused ring structure with the aromatic group that forms a part of the ligand backbone.
34 . The complex of claim 33 , wherein the aromatic group that is part of the backbone as combined with two or more R 4 groups that have formed a fused ring are substituted or unsubstituted nathphalene, substituted or unsubstituted quinoline or substituted or unsubstituted indole.
35 . The complex of claim 30 , wherein R 1 is a substituted or unsubstituted phenyl such that the compound can be characterized by one of the following general formulas:
wherein R 1 , R 3 , R 4 , X, M, L, n, m, a and b each have the definition given above, R 5 is selected from the group consisting of electron withdrawing and electron donating groups; and c is 0, 1, 2, 3, 4 or 5.
36 . The complex of claim 35 , wherein R 5 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, silyl, amino, alkoxy, aryloxy, phosphino, boryl, transition metals, halogens and combinations thereof.
37 . A composition of matter comprising the compound of claim 1 and a metal precursor characterized by the general formula M(L) n , where M is a transition metal selected from the group consisting of Groups 4, 5, 6, 7, 8, 9, 10, 11 and 12 of the Periodic Table of Elements; L is independently each occurrence, a ligand; and n is a number 0, 1, 2, 3, 4, and 5.
38 . The composition of claim 37 wherein the ratio of compound to metal precursor is in the range of about 0.01:1 to about 100:1.
39 . The composition of claim 38 , wherein the ratio of compound to metal precursor is in the range of about 0.5:1 to about 20:1.
40 . The composition of claim 37 , wherein the compound is of claim 1 .
41 . The composition of claim 37 , wherein the compound is of claim 16 .
42 . An array comprising a plurality of compounds wherein each compound can be characterized by the general formula:
wherein each R 1 , R 2 and R 3 is independently selected from the group consisting of hydrogen, halogens, alkyl, s ubstituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, R 1 and R 2 are joined together in a ring structure;
Q 1 and Q 2 are, independently, selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, Q 1 and Q 2 are joined together in a ring structure;
X is selected from the group consisting of oxygen, nitrogen, sulfur and phosphorus; and a is 1 or 2 depending on X.
43 . The array of claim 42 , wherein each of said plurality of compounds has a different composition.
44 . The array of claim 42 , wherein each of said plurality of compounds is at a selected region on a substrate such that each compound is isolated from the other compounds.
45 . The array of claim 42 , wherein said plurality of compounds comprises at least 10 compounds each having a different composition.
46 . The array of claim 45 , wherein said plurality of compounds comprises at least 25 compounds each having a different composition.
47 . The array of claim 46 , wherein said plurality of compounds comprises at least 50 compounds each having a different composition.
48 . The array of claim 44 , wherein said substrate is a microtiter plate.
49 . The array of claim 44 , wherein said plurality of compounds are at least 50% pure within said regions.
50 . A transition metal-catalyzed reaction employing complex in claim 20 .
51 . The reaction of claim 50 , wherein the reaction involves C—H, C—C, C—N, C—O, C—S, C—P, C—B and C—Si bond formation.
52 . The reaction of claim 51 , wherein C—H, C—C, C—N, C—O, C—S, C—P, C—B, and C—Si bond formation involves a sp 2 -hybridized C atom.
53 . The reaction of claim 52 , wherein the reactions involve carbonylation, hydroformylation, hydroxycarbonylation, hydrocarbonylation, hydroesterification, hydrogenation, hydrosilylation, hydroboration, hydroamination, epoxidation, aziridination, reductive amination, C—H activation, insertion, C—H activation-insertion, C—H activation-substitution, C-halogen activation, C-halogen activation-substitution, C-halogen activation-insertion, alkene metathesis, alkyne metathesis, polymerization, alkene oligomerization, alkene polymerization, alkyne oligomerization, alkyne polymerization, co-polymerization, CO-alkene co-oligomerization, CO-alkene co-polymerization, CO-alkyne co-oligomerization, and CO-alkyne co-polymerization.
54 . A polymerization or oligomerization reaction employing a compound characterized by the general formula:
wherein each R 1 , R 2 and R 3 is independently selected from the group consisting of hydrogen, halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, R 1 and R 2 are joined together in a ring structure;
Q 1 and Q 2 are, independently, selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, Q 1 and Q 2 are joined together in a ring structure;
X is selected from the group consisting of oxygen, nitrogen, sulfur and phosphorus; and a is 1 or 2 depending on X.
55 . The reaction of claim 54 , wherein each of R 1 and R 2 is independently selected from the group consisting of alkyl, substituted alkyl, heteroalkyl, cycloalkyl, substituted cycloalkyl, aryl and substituted aryl.
56 . The reaction of claim 54 , wherein Q 1 and Q 2 are joined together in a ring structure with the backbone of the compound, such that the compound can be characterized by the general formula:
wherein R 1 , R 2 , R 3 , X and a each have the definition given above; R 4 is selected from the group consisting of electron withdrawing and electron donating groups; and b is 0, 1, 2, 3 or 4.
57 . The reaction of claim 56 , wherein R 4 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, silyl, amino, alkoxy, aryloxy, phosphino, boryl, transition metals, halogens and combinations thereof.
58 . The reaction of claim 57 , wherein b is 1, 2 or 3 and R 4 is selected from the group consisting of methyl, ethyl, propyl, butyl, pentyl, phenyl, cyano, acetyl, benzoyl, nitro, dimethylamino, diethylamino, methylphenylamino, benzylmethylamino, trimethylsilyl, dimethylboryl, diphenylboryl, methylphenylboryl, dimethoxyboryl, chromium tricarbonyl, ruthenium tricarbonyl, cyclopentadienyl iron and isomers thereof where applicable.
59 . The reaction of claim 56 , wherein two or more R 4 groups combine to form a fused ring structure with the aromatic group that forms a part of the ligand backbone.
60 . The reaction of claim 59 , wherein the aromatic group that is part of the backbone as combined with two or more R 4 groups that have formed a fused ring are substituted or unsubstituted naphthalene, substituted or unsubstituted quinoline or substituted or unsubstituted indole.
61 . The reaction of claim 56 , wherein R 1 is a substituted or unsubstituted phenyl such that the compound can be characterized by the general formula:
wherein R 2 , R 3 , R 4 , X, a and b each have the definition given above, R is selected from the group consisting of electron withdrawing and electron donating groups; and c is 0, 1, 2, 3, or 5.
62 . The reaction of claims 61 , wherein R 5 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, silyl, anino, alkoxy, aryloxy, phosphino, boryl, transition metals, halogens and combinations thereof.
63 . A process for polymerizing or oligomerizing an olefin, diolefin or acetylenically unsaturated compound, comprising contacting said olefin, diolefin or acetylenically unsaturated compound to a complex that can be characterized by one of the following general formulas:
wherein each R 1 , R 2 and R 3 is independently selected from the group consisting of hydrogen, halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, R 1 and R 2 are joined together in a ring structure;
Q 1 and Q 2 are, independently, selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, Q 1 and Q 2 are joined together in a ring structure;
X is selected from the group consisting of oxygen, nitrogen and phosphorus; a is 0, 1 or 2 depending on X and the type of bonding to M;
M is a transition metal selected from the group consisting of Groups 4, 5, 6, 7, 8, 9 and 10 of the Periodic Table of Elements;
L is independently each occurrence, a ligand;
n is a number 0, 1, 2, 3, 4, and 5; and
m is 1, 2, 3 or 4.
64 . The process of claim 63 , further including an activator.
65 . The process of claim 63 , further comprising the step of subjecting the complex to an activating technique.
66 . The process of claim 63 , wherein M is selected from the group consisting of Sc, Y, Zr, Ti, Hf, V, Nb, Ta, Cr, Mo, W, Mn, Re, Fe, Ru, Os, Co, Rh, Ni and Pd.
67 . The process of claim 63 , wherein L is selected from the group consisting of hydrogen, halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, cyclopentadienyl, substituted cyclopentadienyl, imido, oxo and combinations thereof.
68 . The process of claim 63 , wherein L is selected from the group consisting of carbon monoxide, isocyanide, nitrous oxide, PA 3 , NA 3 , OA 2 , SA 2 , SeA 2 , and combinations thereof, wherein each A is independently selected from a group consisting of alkyl, substituted alkyl, heteroalkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, and amino.
69 . The process of claim 63 , wherein said process is a continuous process at a temperature of between −100° C. and 500° C.
70 . A process for making a compound characterized by the general formula: formula:
wherein each R 1 , R 2 and R 3 is independently selected from the group consisting of hydrogen, halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, R 1 and R 2 are joined together in a ring structure;
Q 1 and Q 2 are, independently, selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, Q 1 and Q 2 are joined together in a ring structure;
X is selected from the group consisting of oxygen, nitrogen, sulfur and phosphorus; and a is 1 or 2 depending on X;
the step of the process comprising:
reacting a compound characterized by the general formula:
where X′ is selected from the group consisting of chloro, bromo, iodo, triflate, nonaflate, alkyl sulfonates, aryl sulfonates and tosylate;
with an amine characterized by the general formula HNR 1 R 2 , where R 1 and R 2 are as defined above.
71 . The process of claim 70 , wherein the step employs a catalyst that is a composition comprising M′ and L′ where M′ a homogeneous or heterogeneous metal precursor catalyst or catalyst and L′ is a phosphine or nitrogen containing ligand.
72 . The process of claim 71 , wherein L′ is ligand that is either bidentate, tridentate or hemi-labile and is unsubstituted or substituted, supported or unsupported, water-soluble or insoluble, soluble or insoluble in organic solvents.
73 . The process of claim 71 , wherein M′ includes a metal selected from the group consisting of Pd, Ni or Pt.
74 . An array comprising a plurality of complexes wherein each complex can be characterized by one of the following general formulas:
wherein each R 1 , R 2 and R 3 is independently selected from the group consisting of hydrogen, halogens, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heteroalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, R 1 and R 2 are joined together in a ring structure;
Q 1 and Q 2 are, independently, selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkoxy, aryloxy, silyl, boryl, phosphino, amino, thio, seleno, and combinations thereof; optionally, Q 1 and Q 2 are joined together in a ring structure;
X is selected from the group consisting of oxygen, nitrogen, sulfur and phosphorus; a is 0, 1 or 2 depending on X and the type of bonding to M;
M is a transition metal selected from the group consisting of Groups 4, 5, 6, 7, 8, 9, 10, 11 and 12 of the Periodic Table of Elements;
L is independently each occurrence, a ligand;
n is a number 0, 1, 2, 3, 4, and 5; and
m is 1, 2, 3 or 4.Join the waitlist — get patent alerts
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