US2002032467A1PendingUtilityA1

Signal delivery through the right ventricular septum

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Priority: May 4, 2000Filed: May 3, 2001Published: Mar 14, 2002
Est. expiryMay 4, 2020(expired)· nominal 20-yr term from priority
Inventors:Itsik ShemerYival Mika
A61N 1/36843A61N 1/36842A61B 5/029A61N 1/36542A61N 1/36514A61B 2018/00392A61B 2017/0243A61B 5/6858A61N 1/3628A61B 5/6843A61N 1/36585A61B 5/6859A61N 1/36564A61B 5/0215A61N 1/36557A61B 2017/00243A61B 5/6852A61B 18/20A61B 5/6856A61B 5/6853A61B 5/145A61N 1/3627A61N 1/056A61B 2017/00247A61B 5/287
26
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Claims

Abstract

Apparatus for applying a signal to a heart of a human subject is provided. The apparatus includes a set of one or more electrodes, adapted to be coupled to the right ventricular septum of the heart. A control unit of the apparatus is adapted to drive the electrode set to apply an Excitable-Tissue Control (ETC) signal to the septum. Preferably, the control unit is adapted to configure the signal to be capable of modifying contractility of a portion of the heart.

Claims

exact text as granted — not AI-modified
1 . A method for applying a signal to a heart of a human subject, comprising applying an Excitable-Tissue Control (ETC) signal to a site on the right ventricular septum of the heart.  
     
     
         2 . A method according to  claim 1 , wherein applying the ETC signal comprises configuring the signal to be capable of modifying contractility of a portion of the heart.  
     
     
         3 . A method according to  claim 2 , wherein configuring the ETC signal comprises configuring the signal to be capable of modifying contractility of the left ventricle of the heart.  
     
     
         4 . A method according to  claim 2 , wherein configuring the ETC signal comprises configuring the signal to be capable of modifying contractility of the septum.  
     
     
         5 . A method according to  claim 2 , wherein configuring the ETC signal comprises configuring the signal to be capable of modifying contractility of the right ventricle of the heart.  
     
     
         6 . A method according to  claim 2 , wherein configuring the ETC signal comprises configuring the signal to be capable of increasing contractility of the portion of the heart.  
     
     
         7 . A method according to  claim 2 , wherein configuring the ETC signal comprises configuring the signal to be capable of decreasing contractility of the portion of the heart.  
     
     
         8 . A method according to  claim 7 , wherein configuring the ETC signal to be capable of decreasing the contractility comprises configuring the signal to be capable of decreasing contractility of the septum.  
     
     
         9 . A method according to  claim 1 , wherein applying the ETC signal comprises applying a series of biphasic pulses.  
     
     
         10 . A method according to  claim 1 , wherein applying the ETC signal comprises applying a series of generally square pulses.  
     
     
         11 . A method according to  claim 1 , wherein applying the ETC signal comprises applying a series of pulses at a rate greater than about 50 Hz.  
     
     
         12 . A method according to  claim 1 , wherein applying the ETC signal comprises applying a series of pulses at a rate less than about 100 Hz.  
     
     
         13 . A method according to  claim 1 , wherein applying the ETC signal comprises applying a series of pulses at a rate between about 50 Hz and 100 Hz.  
     
     
         14 . A method according to  claim 1 , wherein applying the ETC signal comprises applying a series of pulses which are greater than about 8 mA.  
     
     
         15 . A method according to  claim 14 , wherein applying the ETC signal comprises applying a series of pulses which are greater than about 10 mA.  
     
     
         16 . A method according to  claim 1 , wherein applying the ETC signal comprises applying the ETC signal to a site at or adjacent to an intersection of the septum and the right ventricular free wall.  
     
     
         17 . Apparatus for applying a signal to a heart of a human subject, comprising: 
 a set of one or more electrodes, adapted to be coupled to the right ventricular septum of the heart; and    a control unit, adapted to drive the electrode set to apply an Excitable-Tissue Control (ETC) signal to the septum.    
     
     
         18 . Apparatus according to  claim 17 , wherein the control unit is adapted to configure the signal to be capable of modifying contractility of a portion of the heart.  
     
     
         19 . Apparatus according to  claim 18 , wherein the control unit is adapted to configure the signal to be capable of modifying contractility of the left ventricle of the heart.  
     
     
         20 . Apparatus according to  claim 18 , the control unit is adapted to configure the signal to be capable of modifying contractility of the septum.  
     
     
         21 . Apparatus according to  claim 18 , wherein the control unit is adapted to configure the signal to be capable of modifying contractility of the right ventricle of the heart.  
     
     
         22 . Apparatus according to  claim 18 , wherein the control unit is adapted to configure the signal to be capable of increasing contractility of the portion of the heart.  
     
     
         23 . Apparatus according to  claim 18 , wherein the control unit is adapted to configure the signal to be capable of decreasing contractility of the portion of the heart.  
     
     
         24 . Apparatus according to  claim 23 , wherein the control unit is adapted to configure the signal to be capable of decreasing contractility of the septum.  
     
     
         25 . Apparatus according to  claim 17 , wherein the control unit is adapted to drive the elect rode s et to apply a series of biphasic pulses.  
     
     
         26 . Apparatus according to  claim 17 , wherein the control unit is adapted to drive the electrode set to apply a series of generally square pulses.  
     
     
         27 . Apparatus according to  claim 17 , wherein the control unit is adapted to drive the electrode set to apply a series of pulses at a rate greater than about 50 Hz.  
     
     
         28 . Apparatus according to  claim 17 , wherein the control unit is adapted to drive the electrode set to apply a series of pulses at a rate less than about 100 Hz.  
     
     
         29 . Apparatus according to  claim 17 , wherein the control unit is adapted to drive the electrode set to apply a series of pulses at a rate between about 50 Hz and 100 Hz.  
     
     
         30 . Apparatus according to  claim 17 , wherein the control unit is adapted to drive the electrode set to apply a series of pulses which are greater than about 8 mA.  
     
     
         31 . Apparatus according to claim  30 , wherein the control unit is adapted to drive the electrode set to apply a series of pulses which are greater than about 10 mA.  
     
     
         32 . Apparatus according to  claim 17 , wherein the control unit is adapted to drive the electrode set to apply the ETC signal to a site at or adjacent to an intersection of the septum and the right ventricular free wall.

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