US2002006904A1PendingUtilityA1

Method of treating inflammation in the joints of a body

Priority: May 10, 2000Filed: May 9, 2001Published: Jan 17, 2002
Est. expiryMay 10, 2020(expired)· nominal 20-yr term from priority
Inventors:Allan R. Dunn
A61P 19/02Y10S530/84A61K 38/27
42
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Claims

Abstract

A process for treating inflammation in a joint whether heat, redness, pain, swelling and/or stiffness, and for increasing motion and increasing joint space and correcting mal-alignment, comprising the steps of dissolving a quantity of growth hormone (somatotropin), preferably in purified form, in a buffer solution, and injecting one time or multiple repeat times, a single dosage of the mixture of purified growth hormone and buffer solution into the joint of a body so as to initiate the treatment process. The present invention is also directed to a process of preparing a joint for treatment of inflammation, as described herein, by injecting or otherwise applying one or more of a group of agents, such as an anti-growth factor, an anti-cytokine or an anti-kinase (or a combination thereof) to quiet and reduce deleterious activity in the joint. This preparation step can be carried out either simultaneously or prior to the step of injecting the mixture of purified growth hormone (commonly known as somatotropin) and a buffer solution into the joint, whether of a human or other animal.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . A method of treating inflammation in a joint of a body comprising the steps of: 
 a) injecting a quantity of an anti-growth agent into the joint; and    b) subsequently dissolving a quantity of purified growth hormone in a buffer solution and injecting a single dosage of said growth hormone and said buffer solution into said joint.    
     
     
         2 . A method as recited in  claim 1  wherein said anti-growth agent is an anti-cytokines agent.  
     
     
         3 . A method as recited in  claim 1  wherein said anti-growth agent is an anti-kinases agent.  
     
     
         4 . A method as recited in  claim 1  wherein said purified growth hormone comprises between 0.5 milligrams to 10.0 milligrams per milliliter of a buffer solution.  
     
     
         5 . A method of treating inflammation in a rheumatoid joint of a body comprising the steps of: 
 a) injecting a quantity of an anti-cytokines agent into the joint; and    b) subsequently dissolving a quantity of purified growth hormone in a buffer solution and injecting a single dosage of said growth hormone and said buffer solution into said joint.    
     
     
         6 . An anti-inflammatory composition comprising an anti-growth agent and a purified growth hormone in an amount between 0.5 milligrams to 10.0 milligrams per milliliter of a buffer solution.  
     
     
         7 . An anti-inflammatory composition as recited in  claim 6  wherein said anti-growth agent is an anti-cytokines agent.  
     
     
         8 . An anti-inflammatory composition as recited in  claim 6  wherein said anti-growth agent is an anti-kinases agent.  
     
     
         9 . An anti-inflammatory composition as recited in  claim 6  further comprising a lubricating agent.  
     
     
         10 . An anti-inflammatory composition as recited in  claim 9  wherein said lubricating agent is hyaluronic acid.  
     
     
         11 . An anti-inflammatory composition comprising an anti-cytokine and a purified growth hormone in an amount between 0.5 milligrams to 10.0 milligrams per milliliter of a buffer solution.  
     
     
         12 . An anti-inflammatory composition comprising an anti-kinase and a purified growth hormone in an amount between 0.5 milligrams to 10.0 milligrams per milliliter of a buffer solution

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