Agent for preventing and/or treating multiple organ failure

Abstract

The present invention is to provide an agent for preventing and/or treating multiple organ failure comprising Tumor cytotoxic factor-II (TCF-II) or Hepatocyte growth factor (HGF) as an effective ingredient. The agent of the present invention will be useful for preventing and/or treating the development from burn, disseminated intravascular coagulation (DIC), circulatory failure, hemorrhagic shock, infectious disease, acute pancreatitis, ischemic disorder, hepatorenal syndrome, gastrointestinal hemorrhage, nutritional metabolic failure, terminal cancer, acquired immunodeficiency syndrome (AIDS), deterioration of systemic conditions due to radiation affection and cachexia etc. to multiple organ failure.

1 . An agent for preventing and/or treating multiple organ failure comprising Tumor cytotoxic factor-II (TCF-II) or Hepatocyte growth factor (HGF) as an effective ingredient.  
     
     
         2 . The agent according to    claim 1    wherein said multiple organ failure is one induced by administration of chemical substances.  
     
     
         3 . The agent according to    claim 2    wherein said chemical substance is endotoxin.  
     
     
         4 . The agent according to    claim 2    wherein said chemical substance is dimethylnitrosamine.  
     
     
         5 . The agent according to    claim 2    wherein said chemical substance is tripsin.  
     
     
         6 . The agent according to    claim 1    wherein said multiple organ failure is one with a primary cause of drug intoxication.  
     
     
         7 . The agent according to    claim 6    wherein said drug is thioacetamide or acetaminophen.  
     
     
         8 . The agent according to    claim 1    wherein said multiple organ failure is one with a primary cause of renal insufficiency induced by mercuric chloride.  
     
     
         9 . The agent according to    claim 1    wherein said multiple organ failure is one induced by burn.