US2001027213A1PendingUtilityA1
Use of pyrethroid compounds to promote hair growth
Priority: Nov 20, 1998Filed: May 16, 2001Published: Oct 4, 2001
Est. expiryNov 20, 2018(expired)· nominal 20-yr term from priority
A61P 17/14A61K 8/40A61K 31/277A61Q 7/00
35
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Claims
Abstract
A method of promoting hair growth which includes administering to a subject an effective amount of a pyrethroid. A composition having a pyrethroid and a pharmaceutically acceptable carrier for promoting hair growth is also described.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A method of promoting hair growth comprising administering to a subject an effective amount of a pyrethroid.
2 . The method of claim 1 , wherein the pyrethroid is a type I pyrethroid.
3 . The method of claim 1 , wherein the pyrethroid is a type II pyrethroid.
4 . The method of claim 1 , wherein the pyrethroid is cypermethrin, deltamethrin, or fenvalerate.
5 . The method of claim 1 , wherein the pyrethroid is administered topically.
6 . The method of claim 1 , wherein the pyrethroid is provided in a sterile composition.
7 . The method of claim 6 , wherein the weight percent of the pyrethroid ranges from 0.005% to 5%.
8 . The method of claim 7 , wherein the weight percent of the pyrethroid ranges from 0.01% to 2%.
9 . A method of promoting hair growth comprising administering to a subject an effective amount of a compound of the formula:
in which each of R a , R b , R c , and R d , independently, is H, fluoro, chloro, bromo, iodo, or C 1-4 alkyl; R 2 is CN or C≡CH; and R 3 is
in which X is O, S, NH, or CH 2 ; and each of R′ and R″, independently, is H, fluoro, chloro, bromo, iodo, or C 1-4 alkyl; or a salt thereof.
10 . The method of claim 9 , wherein said compound is administered topically.
11 . The method of claim 9 , wherein said compound is provided in a sterile composition.
12 . The method of claim 9 , wherein R 2 is CN.
13 . The method of claim 12 , wherein R 1 is
in which each of R a , R b and R c , independently, is H, fluoro, chloro, bromo, iodo, or C 1-4 alkyl.
14 . The method of claim 13 , wherein each of R a and R b , independently, is chloro or bromo; and R c is H.
15 . The method of claim 14 , wherein each of R a and R b , independently, is chloro.
16 . The method of claim 15 , wherein X is O; and each of R′ and R″, independently, is H.
17 . The method of claim 14 , wherein each of R a and R b , independently, is bromo.
18 . The method of claim 17 , wherein X is O; and each of R′ and R″, independently, is H.
19 . The method of claim 12 , wherein R 1 is
in which R d is H, fluoro, chloro, bromo, iodo, or C 1-4 alkyl.
20 . The method of claim 19 , wherein R d is chloro.
21 . The method of claim 20 , wherein X is O; and each of R′ and R″, independently, is H.
22 . The method of claim 12 , wherein X is O.
23 . The method of claim 22 , wherein each of R′ and R″, independently, is H.
24 . A composition for promoting hair growth comprising a pyrethroid and a pharmaceutically acceptable carrier.
25 . The composition of claim 24 , wherein the pyrethroid is a type I pyrethroid.
26 . The method of claim 24 , wherein the pyrethroid is a type II pyrethroid.
27 . The method of claim 24 , wherein the pyrethroid is cypermethrin, deltamethrin, or fenvalerate.
28 . The composition of claim 24 , said composition being sterile.
29 . The composition of claim 24 , further comprising a fragrance.
30 . The composition of claim 24 , wherein the weight percent of the pyrethroid ranges from 0.005% to 5%.
31 . The composition of claim 30 , wherein the weight percent of the pyrethroid ranges from 0.01% to 2%.Join the waitlist — get patent alerts
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