Methods of use of antimicrobial compounds against pathogenic mycoplasma bacteria

Abstract

This invention relates, in part, to newly identified methods of using quinolone antibiotics, particularly a gemifloxacin compound against certain pathogenic bacteria.

What is claimed is:  
     
         1 . A method for modulating metabolism of pathogenic Mycoplasma bacteria comprising the step of contacting pathogenic Mycoplasma bacteria with an antibacterially effective amount of a composition comprising a gemifloxacin compound, or antibacterially effective derivatives thereof.  
     
     
         2 . The method of    claim 1    wherein said pathogenic Mycoplasma bacteria is selected from the group consisting of: 
   Mycoplasma pneumoniae, M. hominis, M. fermentans, M. genitalium, M. penetrans  and  Ureaplasma urealyticum.    
 
     
     
         3 . A method of treating or preventing a bacterial infection by pathogenic Mycoplasma bacteria comprising the step of administering an antibacterially effective amount of a composition comprising a gemifloxacin compound to a mammal suspected of having or being at risk of having an infection with pathogenic Mycoplasma bacteria.  
     
     
         4 . The method of    claim 3    wherein said pathogenic Mycoplasma bacteria is selected from the group consisting of: 
   Mycoplasma pneumoniae, M. hominis, M. fermentans, M. genitalium, M. penetrans  and  Ureaplasma urealyticum.    
 
     
     
         5 . The method of    claim 1    wherein said modulating metabolism is inhibiting growth of said bacteria.  
     
     
         6 . The method of    claim 1    wherein said modulating metabolism is killing said bacteria.  
     
     
         7 . The method of    claim 1    wherein said contacting said bacteria comprises the further step of introducing said composition into a mammal.  
     
     
         8 . The method of    claim 3    wherein said mammal is a human.  
     
     
         9 . The method of    claim 7    wherein said mammal is a human.  
     
     
         10 . The method of    claim 1    wherein said bacteria is selected from the group consisting of:  Mycoplasma pneumoniae, M. hominis, M. fermentans, M. genitalium, M. penetrans  and  Ureaplasma urealyticum.    
     
     
         11 . The method of    claim 1    wherein said bacteria is selected from the group consisting of:  Mycoplasma pneumoniae, M. hominis, M. fermentans, M. genitalium, M. penetrans  and  Ureaplasma urealyticum.