US2001012832A1PendingUtilityA1

Method of hormone treatment for patients with symptoms consistent with multiple sclerosis

Priority: Aug 25, 1999Filed: Feb 12, 2001Published: Aug 9, 2001
Est. expiryAug 25, 2019(expired)· nominal 20-yr term from priority
A61K 38/27
47
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Claims

Abstract

A method for patients having symptoms consistent with multiple sclerosis comprising administering a regimen of doses of human growth hormone of less than 0.5 mg/day. In one aspect, the method includes replenishing one or more of melatonin, thymus, thyroid, adrenal and sex hormones to predetermined levels in conjunction with the human growth hormone.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
         1 . A method comprising: 
 in a human subject having symptoms consistent with multiple sclerosis, administering a regimen of doses of human growth hormone of less than 0.5 mg. per day.    
     
     
         2 . The method of    claim 1   , wherein administering the regimen of human growth hormone comprises subcutaneous injections of doses of human growth hormone.  
     
     
         3 . The method of    claim 2   , wherein the regimen for injections comprises twice daily.  
     
     
         4 . The method of    claim 1   , further comprising prior to administering a regimen of human growth hormone measuring the level of human growth hormone in a human subject's blood to determine that the level of human growth hormone is below a predetermined physiological level for an adult human.  
     
     
         5 . The method of    claim 4   , further comprising measuring a level of supplemental hormones selected from the group consisting of sex hormone, melatonin hormone, adrenal hormone, thyroid hormone and thymus hormone to determine that at least one of the hormones is below a predetermined level for an adult human; and replenishing the level of the at least one supplemental hormone to a predetermined physiological level.  
     
     
         6 . A method comprising: 
 measuring a sample of a human subject's blood, the human subject having symptoms consistent with multiple sclerosis, to determine that the level of human growth hormone is below a predetermined physiological level for an adult human; and    replenishing the level of human growth hormone to the predetermined physiological level.    
     
     
         7 . The method of    claim 6   , wherein replenishing the level of human growth hormone comprises subcutaneous injections of doses of human growth hormone.  
     
     
         8 . The method of    claim 7   , wherein a replenishment regimen comprises injections twice daily.  
     
     
         9 . The method of    claim 6   , further comprising measuring a level of supplemental hormones in the human subject's blood, the supplemental hormones selected from the group consisting of sex hormone, melatonin hormone, adrenal hormone, thyroid hormone and thymus hormone to determine that at least one of the hormones is below a predetermined level for an adult human; and 
 replenishing the level of the at least one supplemental hormone to a predetermined physiological level.    
     
     
         10 . A kit for treating symptoms associated with multiple sclerosis comprising human growth hormone and at least one of the supplemental hormones selected from the group consisting of sex hormone, melatonin hormone, adrenal hormone, thyroid hormone, and thymus hormone, the kit for establishing a regimen for the replenishment of the human growth hormone and the at least one of the supplemental hormones to predetermined physiological levels.  
     
     
         11 . The kit of    claim 10   , wherein the amount of human growth hormone is provided in intravenous unit form in doses of less than 0.5 mg per day.  
     
     
         12 . The kit of    claim 11   , wherein the amount of human growth hormone is administered twice daily.  
     
     
         13 . The kit of    claim 10   , wherein the sex hormone comprises at least one of testosterone, progesterone, and estrogen.

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