Simulated cervical tissue and methods for making and using the same

Abstract

Described herein, the disclosure, in one aspect, relates to simulated cervical tissues composed of a gel and red-toned pigment, wherein the cervical tissue has a first face, wherein the first face includes one or more simulated lesions. Methods for constructing the simulated cervical tissue are also disclosed. Additionally, disclosed are kits composed of two or more simulated cervical tissues as described herein, wherein the simulated cervical tissues are different from each based on (1) the number of simulated lesions on each first face of each simulated cervical tissue, (2) the position of the simulated lesions on each first face of each simulated cervical tissue, or a combination thereof. The simulated cervical tissues and kits described herein are useful training tool for performing colposcopies and cam be incorporated into cervical trainers.

What is claimed is: 
     
         1 . A simulated cervical tissue comprising a gel and red-toned pigment, wherein the cervical tissue has a first face, wherein the first face comprises one or more simulated lesions, and the first face has a depression positioned approximately in the center of the first face. 
     
     
         2 . The simulated cervical tissue of  claim 1 , wherein the one or more simulated lesions independently have a diameter of from about 0.2 cm to about 0.7 cm. 
     
     
         3 . The simulated cervical tissue of  claim 1 , wherein the one or more simulated lesions independently have a stromal depth of from about 0.1 cm to about 0.3 cm. 
     
     
         4 . The simulated cervical tissue of  claim 1 , wherein the red-toned pigment comprises a silicone pigment. 
     
     
         5 . The simulated cervical tissue of  claim 1 , wherein the gel comprises a medical gel. 
     
     
         6 . The simulated cervical tissue of  claim 1 , wherein the gel comprises gelatin. 
     
     
         7 . The simulated cervical tissue of  claim 1 , wherein the gel comprises 100% gelatin. 
     
     
         8 . The simulated cervical tissue of  claim 1 , wherein the gel is 100% gelatin having a density of from about 800 kg/m 3  to about 850 kg/m 3 . 
     
     
         9 . The simulated cervical tissue of  claim 1 , wherein the gel is 100% gelatin having a density of from about 800 kg/m 3  to about 850 kg/m 3  and a Young's modulus of from about 300 kPa to about 350 kPa. 
     
     
         10 . The simulated cervical tissue of  claim 1 , wherein the weight ratio of the gel to the red-toned pigment is from 0.001% total gel weight to 3% total gel weight. 
     
     
         11 . The simulated cervical tissue of  claim 1 , wherein the simulated lesion comprises a fluorescent pigment. 
     
     
         12 . The simulated cervical tissue of  claim 1 , wherein the simulated lesion comprises a fluorescent silicone pigment. 
     
     
         13 . The simulated cervical tissue of  claim 1 , wherein the simulated cervical tissue has a thickness of from about 1 cm to about 4 cm. 
     
     
         14 . A cervical model comprising the simulated cervical tissue of  claim 1 . 
     
     
         15 . A kit comprising two or more simulated cervical tissues, wherein the simulated cervical tissues are different from each based on (1) the number of simulated lesions on each first face of each simulated cervical tissue, (2) the position of the simulated lesions on each first face of each simulated cervical tissue, or a combination thereof, and wherein each simulated cervical tissue comprises a gel and red-toned pigment, wherein the cervical tissue has a first face, wherein the first face comprises one or more simulated lesions. 
     
     
         16 . The kit of  claim 15 , wherein the kit comprises from 2 to 10 simulated cervical tissues.