US12497588B2ActiveUtilityA1

Device and method for separating and recovering intestinal contents and extract thereof

Assignee: L&G BIOTECHNOLOGY YANGZHOU CO LTDPriority: Dec 30, 2019Filed: May 14, 2020Granted: Dec 16, 2025
Est. expiryDec 30, 2039(~13.4 yrs left)· nominal 20-yr term from priority
B01D 69/02B01D 61/18B01D 63/087C12M 25/02C12N 1/20Y02A50/30B01D 2325/02B01D 2325/02834B01D 2325/02833B01D 2325/026B01D 2315/10B01D 2313/14C12N 1/02
35
PatentIndex Score
0
Cited by
14
References
5
Claims

Abstract

A device and method for separating and recovering intestinal contents, comprising removing the impurities from the intestinal contents by means of coarse filtration and cross-flow fine filtration, followed by obtaining a concentrate by microporous membrane cross-flow filter, and collecting the target contents. The microporous membrane has a spongy porous structure, and can rapidly and effectively achieve the separation and recovery of flora from the intestinal contents by cooperation with cross-flow filtration. The separated and recovered dry flora comprises at least 10-20% of the initial wet intestinal contents, and comprises at least 10 11 /1 g dry flora.

Claims

exact text as granted — not AI-modified
We claim: 
     
         1 . A device for separating rand recovering intestinal contents, characterized in that the device comprising an impurity removal module and a target content collection module; wherein the impurity removal module is configured to remove impurity from the intestinal contents, comprise a stirring coarse filtration module and a fine filtration module; said stirring coarse filtration module having a liquid inlet and reflux port, said fine filtration module comprising a fine filtration cross-flow disc filter and a liquid storage box, and the penetrating fluid filtered by the fine filtration cross-flow disc filter is passed into the liquid storage box, and then into said target content collection module, a finely penetrating fluid is refluxed via a pipe through the reflux port back into the coarse filtration module, and mixed with the penetrating fluid under the coarse filtration, whereby forming a recycling loop; the target content collection module comprises a microporous membrane cross-flow filter, the microporous membrane has a spongy porous structure with a pore size of 0.01-20 μm, the microporous membrane has a porosity of 30% or more, and the microporous membrane is a hydrophilic film; the microporous membrane cross-flow filter has a disk-like structure, and is internally provided with a spiral flow channel; the ratio of an effective filtration area of a cross-flow disk to an overall area of the cross-flow disk is 0.3-0.9; said target content collection module is connected with the liquid storage box through the pipe, concentrated liquids of said target content collection module is refluxed back into said liquid storage box through the pipe, and mixed with penetrating liquids of the fine filtration module, whereby forming another recycling loop. 
     
     
         2 . The device of  claim 1 , wherein the ratio of an effective filtration area of a cross-flow disk to an overall area of the cross-flow disk is 0.4-0.8. 
     
     
         3 . The device of  claim 1 , wherein a flow channel of the microporous membrane cross-flow filter is a spiral cross-flow channel. 
     
     
         4 . The device of  claim 1 , wherein a cross-sectional area of a flow channel of the microporous membrane cross-flow filter is less than a cross-sectional area of an inlet pipe, and the ratio of the former to the latter is 0.8, 0.6, or 0.5, or less. 
     
     
         5 . The device of  claim 1 , wherein the microporous membrane comprises one or more of polyether sulfone membrane, cellulose membrane, polymethacrylate membrane which are modified or unmodified.

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