Glycerol and sodium pentaborate based formulation preventing postoperative adhesions

Abstract

A glycerol and sodium pentaborate based formulation developed for preventing postoperative adhesions occurring between manipulated tissues and organs is provided. An objective of the glycerol and sodium pentaborate based formulation is to provide a formulation comprising a mixture of glycerol, wherein the glycerol is one of the most abundant biomolecules in a human body, and sodium pentaborate, wherein the sodium pentaborate is known to have positive effects on a wound healing, with a purpose of preventing the postoperative adhesions.

What is claimed is: 
     
       1. A glycerol and sodium pentaborate based formulation consisting of a mixture of glycerol and sodium pentaborate in a physiological saline solution, wherein the glycerol and sodium pentaborate based formulation blocks fibrosis and collagen production, preventing adhesion between tissues and organs manipulated at a surgical site as a result of surgical intervention. 
     
     
       2. The glycerol and sodium pentaborate based formulation according to  claim 1 , wherein the glycerol has a concentration varying between 1% and 10%. 
     
     
       3. The glycerol and sodium pentaborate based formulation according to  claim 1 , wherein the sodium pentaborate has a concentration varying between 1% and 10%. 
     
     
       4. The glycerol and sodium pentaborate based formulation according to  claim 1 , wherein the glycerol and sodium pentaborate based formulation is in the form of a spray.