US11833123B2ActiveUtilityA1

Pharmaceutical composition

Assignee: KOBAYASHI PHARMACEUTICAL CO LTDPriority: Sep 21, 2018Filed: Sep 2, 2019Granted: Dec 5, 2023
Est. expirySep 21, 2038(~12.2 yrs left)· nominal 20-yr term from priority
Inventors:Ayaka Matsuoka
A61K 31/167A61J 1/1468A61K 9/10A61P 25/02A61K 9/08
50
PatentIndex Score
0
Cited by
14
References
5
Claims

Abstract

The purpose of the present invention is to provide a method for suppressing reduction in the quantity of lidocaines in external pharmaceutical compositions. In a pharmaceutical composition containing lidocaine and/or a salt thereof, the pharmaceutical composition being accommodated in a container of which the inner walls are configured from linear low-density polyethylene, and being such that the carbon number of the side chain of the linear low-density polyethylene is 4 or lower, a reduction in the quantity of lidocaine and/or salt thereof is suppressed.

Claims

exact text as granted — not AI-modified
The invention claimed is: 
     
       1. A pharmaceutical composition, comprising:
 lidocaine and/or a salt thereof, 
 wherein the pharmaceutical composition is placed in a container in which an inner wall is composed of linear low-density polyethylene, and the linear low-density polyethylene has a side chain having a carbon number of 4 or less. 
 
     
     
       2. The pharmaceutical composition according to  claim 1 , wherein the linear low-density polyethylene has a density of 0.932 to 0.940 g/cm 3 . 
     
     
       3. The pharmaceutical composition according to  claim 1 , which is a liquid or a gel. 
     
     
       4. A method of suppressing reduction in weight of lidocaine and/or a salt thereof in a pharmaceutical composition containing lidocaine and/or a salt thereof, comprising the step of:
 placing the pharmaceutical composition in a container in which an inner wall is composed of linear low-density polyethylene and the linear low-density polyethylene has a side chain having a carbon number of 4 or less. 
 
     
     
       5. The pharmaceutical composition according to  claim 2 , which is a liquid or a gel.

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