Fermented milk and polysaccharide with cancerous cachexia inhibitory effect

Abstract

An object of the present invention is to provide a fermented milk and polysaccharide capable of inhibiting cancerous cachexia. A fermented milk with cancerous cachexia inhibitory effect according to one aspect of the present invention contains Lactobacillus delbrueckii subsp. bulgaricus as an active ingredient. Also, polysaccharide with cancerous cachexia inhibitory effect according to another aspect of the present invention are produced from the Lactobacillus delbrueckii subsp. bulgaricus. It is preferable that the Lactobacillus delbrueckii subsp. bulgaricus is Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 (accession number: FERM BP-10741).

The invention claimed is: 
     
       1. A method for inhibiting cancerous cachexia in an individual comprising
 administering a fermented milk comprising  Lactobacillus delbrueckii  subsp.  bulgaricus  to an individual in need thereof, 
 wherein the  Lactobacillus delbrueckii  subsp.  bulgaricus  produces a polysaccharide, and 
 wherein the fermented milk is administered in a quantity such that a dosage of 0.01 mg/kg/day to 1000 mg/kg/day of the polysaccharide is administered to the individual in need thereof. 
 
     
     
       2. The method according to  claim 1 , the  Lactobacillus delbrueckii  subsp.  bulgaricus  is  Lactobacillus delbrueckii  subsp.  bulgaricus  OLL1073R-1 (accession number: FERM BP-10741). 
     
     
       3. A method for inhibiting cancerous cachexia in an individual comprising
 administering a polysaccharide produced from  Lactobacillus delbrueckii  subsp.  bulgaricus  to an individual in need thereof, 
 wherein the polysaccharide is administered in a dosage of 0.01 mg/kg/day to 1000 mg/kg/day. 
 
     
     
       4. The method according to  claim 3 , the  Lactobacillus delbrueckii  subsp.  bulgaricus  is  Lactobacillus delbrueckii  subsp.  bulgaricus  OLL1073R-1 (accession number: FERM BP-10741).