Compositions and methods for modulating and/or stimulating immune responses in human and/or animal

Abstract

There is provided a composition including parietal polysaccharides from at least one Candida species and parietal polysaccharides from at least one different yeast species. The composition can be used in modulating and/or stimulating immune responses in animal or human.

The invention claimed is: 
     
       1. A composition comprising parietal polysaccharides from at least one  Candida  species and parietal polysaccharides from at least one  Saccharomyces  species, wherein the parietal polysaccharides from the at least one  Candida  species and the parietal polysaccharides from at least one  Saccharomyces  species are chitin, mannan-oligosaccharides, Beta-1,3 glucans and Beta-1,6 glucans in an amount ranging from 20 to 80 weight percent based on the total weight of the composition and wherein the parietal polysaccharides from the at least one  Candida  species are in an amount ranging from 10 to 50 dry weight percent based on the total weight of the parietal polysaccharides in the composition. 
     
     
       2. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species are in an amount ranging from 10 to 15 dry weight percent based on the total weight of the parietal polysaccharides in the composition. 
     
     
       3. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species are in an amount of at least 10, 15, 20, 25, 30, 35, 40, 45 or 50 dry weight percent based on the total weight of the parietal polysaccharides in the composition. 
     
     
       4. The composition according to  claim 2 , wherein the parietal polysaccharides from the at least one  Candida  species are in an amount of at least 10, 11, 12, 13, 14 or 15 dry weight percent based on the total weight of the parietal polysaccharides in the composition. 
     
     
       5. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species and the parietal polysaccharides from the at least one  Saccharomyces  species are in an amount ranging from 30 to 60 weight percent based on the total weight of the composition. 
     
     
       6. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species and the parietal polysaccharides from the at least one  Saccharomyces  species are in an amount of at least 20, 23, 25, 27, 30, 33, 35, 37, 40, 43, 45, 47, 50, 53, 55, 57, 60, 63, 65, 67, 70, 73, 75, 77 or 80 weight percent based on the total weight of the composition. 
     
     
       7. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species and the parietal polysaccharides from the at least one  Saccharomyces  species are in an amount of at least 20, 23, 25, 27, 30, 33, 35, 37, 40, 43, 45, 47, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59 or 60 weight percent based on the total weight of the composition. 
     
     
       8. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species are in an amount ranging from 10 to 50 dry weight percent based on the total weight of the parietal polysaccharides in the composition; and the parietal polysaccharides from the at least one  Candida  species and the parietal polysaccharides from the at least one  Saccharomyces  species are in an amount ranging from 30 to 60 weight percent based on the total weight of the composition. 
     
     
       9. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species are in an amount of at least 10, 15, 20, 25, 30, 35, 40, 45 or 50 dry weight percent based on the total weight of the parietal polysaccharides in the composition; and the parietal polysaccharides from the at least one  Candida  species and the parietal polysaccharides from the at least one  Saccharomyces  species are in an amount ranging from 30 to 60 weight percent based on the total weight of the composition. 
     
     
       10. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species are in an amount ranging from 10 to 50 dry weight percent based on the total weight of the parietal polysaccharides in the composition; and the parietal polysaccharides from the at least one  Candida  species and the parietal polysaccharides from the at least one  Saccharomyces  species are in an amount of at least 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 63, 54, 55, 56, 57, 58, 59 or 60 weight percent based on the total weight of the composition. 
     
     
       11. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Candida  species are in an amount of at least 10, 15, 20, 25, 30, 35, 40, 45 or 50 dry weight percent based on the total weight of the parietal polysaccharides in the composition; and the parietal polysaccharides from the at least one  Candida  species and the parietal polysaccharides from the at least one  Saccharomyces  species are in an amount of at least 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59 or 60 weight percent based on the total weight of the composition. 
     
     
       12. The composition according to  claim 1 , wherein the at least one  Candida  species is  Candida utilis.    
     
     
       13. The composition according to  claim 1 , wherein the parietal polysaccharides from the at least one  Saccharomyces  species are from  Saccharomyces cerevisiae  sp. 
     
     
       14. The composition according to  claim 1 , for use in modulating and/or stimulating immune responses in an animal. 
     
     
       15. The composition according to  claim 1 , wherein the at least one  Saccharomyces  species is  Saccharomyces cerevisiae  and the at least one  Candida  species is  Candida utilis  and wherein the parietal polysaccharides from the at least one  Saccharomyces cerevisiae  are in an amount ranging from 30 to 50 weight percent based on the total weight of the composition and wherein the parietal polysaccharides from the  Candida utilis  are in an amount ranging from 5 to 15 weight percent based on the total weight of the composition.