Composition and medical device comprising acetylsalicylic acid for the treatment of human papilloma virus skin infections

Abstract

A medical device for the treatment of papilloma virus (HPV) skin infections is the object of this invention, in particular for the treatment of warts and related pathologies. In particular, this invention relates to acetylsalicylic acid for use in the topical treatment, of HPV skin infections in particular benign infections and more in particular warts. Acetylsalicylic acid may be administered by plaster or patch, both in a solid state, such as a tablet, powder or granulate, and by a hydrophilic or hydrophobic gel.

The invention claimed is: 
     
       1. A method of treating HPV skin infections consisting of administering topically to skin of a patient a therapeutically effective amount of acetylsalicylic acid,
 wherein the acetylsalicylic acid is contained in a patch or plaster, 
 wherein the patch or the plaster consists of acetylsalicylic acid with common excipients, a layer or adhesive material facing the skin to be treated, and an impermeable layer facing outward; and, 
 wherein HPV skin infections in such patient are treated. 
 
     
     
       2. The method according to  claim 1 , wherein the HPV skin infections are of the benign type. 
     
     
       3. The method according to  claim 2 , wherein the HPV skin infections are papillomata, condylomata, condylomata of the male or female genital organs or common, plantar or flat, warts. 
     
     
       4. The method according to  claim 1 , wherein the acetylsalicylic acid is in a solid state or embedded in a polymer matrix. 
     
     
       5. The method according to  claim 1 , wherein the dosage of acetylsalicylic acid is comprised between 0.3 and 5 g/day or between 0.3 and 4 g/day, or between 0.3 and 1.2 g/day, or between 0.5 and 1 g/day. 
     
     
       6. The method according to  claim 1 , wherein the impermeable layer is selected from:
 polyethylene terephthalate film (PET) 
 polyethylene film 
 polyurethane film 
 polyamide film 
 ethylene vinyl alcohol co-polymer (EVA) film 
 laminates comprising two or more layers of film selected from those listed above.