US10626139B2ActiveUtilityA1

Cationic steroidal antimicrobial compounds

55
Individually held — no corporate assignee on recordPriority: Feb 27, 2014Filed: Feb 17, 2015Granted: Apr 21, 2020
Est. expiryFeb 27, 2034(~7.6 yrs left)· nominal 20-yr term from priority
Inventors:Paul B. Savage
C07J 51/00C07J 41/0088C07J 9/00C07J 43/003C07J 41/0055C07J 9/005
55
PatentIndex Score
0
Cited by
305
References
2
Claims

Abstract

Disclosed herein are cationic steroidal antimicrobials (“CSAs” or “ceragenins”) and methods of making the same. Particularly advantageous methods are identified for the synthesis of CSAs. CSAs may be formulated for treating subjects with ailments responsive to CSAs, including but not limited to treating bacterial infections. Accordingly, some embodiments include formulations and methods of administering CSAs.

Claims

exact text as granted — not AI-modified
The invention claimed is: 
     
       1. A cationic steroidal antimicrobial compound selected from the group consisting of: 
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
       and 
       pharmaceutically acceptable salts thereof. 
     
     
       2. A cationic steroidal antimicrobial compound selected from the group consisting of: 
       
         
           
           
               
               
           
         
       
       and 
       pharmaceutically acceptable salts thereof.

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