Topic leaderboard
Bioinformatics
Ranked by the PatentIndex Score — a 1–99 percentile within G16B · public-visibility date · generated 2026
top 25 per window · public-visibility date
Rising· last 2 yrs
Inventors whose newest G16B patents became public in the last 2 years — the current frontier
- 199Charles A. Taylor90 patents · 5,096 citations
- 296Timothy A. Fonte22 patents · 1,084 citations
- 392Amirali Talasaz87 patents · 1,670 citations
- 488David Balaban17 patents · 1,172 citations
- 583Sethuraman Sankaran15 patents · 726 citations
- 679Milena Banjevic52 patents · 1,986 citations
- 775George Gemelos45 patents · 870 citations
- 871Zachary Demko50 patents · 1,782 citations
- 967John Michael Macpherson28 patents · 1,186 citations
- 1063Chuong Do15 patents · 752 citations
- 1158Matthew Hill38 patents · 594 citations
- 1254Bernhard Zimmermann35 patents · 497 citations
- 1350Allison Ryan33 patents · 555 citations
- 1446Helmy Eltoukhy48 patents · 603 citations
- 1542Linda Avey29 patents · 991 citations
- 1638Anne Wojcicki28 patents · 984 citations
- 1733Brian Thomas Naughton36 patents · 1,087 citations
- 1829Styrmir Sigurjonsson32 patents · 443 citations
- 1925Joshua Babiarz16 patents · 324 citations
- 2021Huseyin Eser Kirkizlar17 patents · 319 citations
- 2117Lane A. Eubank15 patents · 317 citations
- 2213Onur Sakarya18 patents · 317 citations
- 238Tudor Pompiliu Constantin15 patents · 317 citations
- 244Serge Saxonov21 patents · 707 citations
- 251Alexander Wong21 patents · 998 citations
Active· last 5 yrs
Sustained G16B output across the last 5 years
- 199Charles A. Taylor90 patents · 5,096 citations
- 296Timothy A. Fonte22 patents · 1,084 citations
- 392Amirali Talasaz87 patents · 1,670 citations
- 488Gilwoo Choi16 patents · 962 citations
- 583Andrew Alexander Kenedy42 patents · 1,482 citations
- 679David Balaban17 patents · 1,172 citations
- 775Jonas Frisen5 patents · 698 citations
- 871Patrik Stahl5 patents · 698 citations
- 967Sethuraman Sankaran15 patents · 726 citations
- 1063Michiel Schaap17 patents · 720 citations
- 1158Milena Banjevic52 patents · 1,986 citations
- 1254George Gemelos45 patents · 870 citations
- 1350Zachary Demko50 patents · 1,782 citations
- 1446John Michael Macpherson28 patents · 1,186 citations
- 1542Chuong Do15 patents · 752 citations
- 1638Matthew Hill38 patents · 594 citations
- 1733Bernhard Zimmermann35 patents · 497 citations
- 1829Gregory R. Hart13 patents · 660 citations
- 1925Allison Ryan33 patents · 555 citations
- 2021Helmy Eltoukhy48 patents · 603 citations
- 2117Linda Avey29 patents · 991 citations
- 2213Anne Wojcicki28 patents · 984 citations
- 238Brian Thomas Naughton36 patents · 1,087 citations
- 244Kwan Chee Chan78 patents · 800 citations
- 251Styrmir Sigurjonsson32 patents · 443 citations
All-time canon
Career PatentIndex Score in G16B
- 199Charles A. Taylor90 patents · 5,096 citations
- 296Timothy A. Fonte22 patents · 1,084 citations
- 392Angela Reynolds106 patents · 5,052 citations
- 488Stephen Scaringe106 patents · 5,052 citations
- 583Steven Read102 patents · 4,605 citations
- 679Andreas Claas9 patents · 2,335 citations
- 775James Casbon9 patents · 2,335 citations
- 871Conrad Lichtenstein7 patents · 2,278 citations
- 967Amirali Talasaz87 patents · 1,670 citations
- 1063Bassil Dahiyat8 patents · 1,539 citations
- 1158Stephen Mayo8 patents · 1,390 citations
- 1254Arthur Street7 patents · 1,356 citations
- 1350D. Gordon7 patents · 1,356 citations
- 1446Michael Josephus Theresia Van Eijk20 patents · 2,459 citations
- 1542Gilwoo Choi16 patents · 962 citations
- 1638Henricus Johannes Adam Van Der Poel13 patents · 1,734 citations
- 1733Robert J. Lipshutz12 patents · 1,654 citations
- 1829Andrew Alexander Kenedy42 patents · 1,482 citations
- 1925Matthew Tobin7 patents · 1,246 citations
- 2021David Balaban17 patents · 1,172 citations
- 2117Jonas Frisen5 patents · 698 citations
- 2213Patrik Stahl5 patents · 698 citations
- 238Dimitris Agrafiotis9 patents · 980 citations
- 244Francis R. Salemme9 patents · 980 citations
- 251Roger F. Bone6 patents · 938 citations
Rising· last 2 yrs
The top-scoring G16B patents made public in the last 2 years
- 199US12217831B2✦ AIArtificial intelligence-based quality scoring36 cites · 202478% earned
- 296US12203142B2✦ AIDetecting mutations and ploidy in chromosomal segments9 cites · 202460% earned
- 392US12100149B2✦ AIDetermining likely response to combination therapies for cardiovascular disease non-invasi13 cites · 202483% earned
- 488US12175354B1Apparatus and method for training a tunable data structure to predict internal ribosome en6 cites · 202478% earned
- 583US12437837B2Reasoning from supervised fine tuning of language fusion models for AI-based protein and d3 cites · 202580% earned
- 679US12182670B1Automated dimensionality reduction for machine learning anomaly detection pipeline16 cites · 202489% earned
- 775US11901083B1Using genetic and phenotypic data sets for drug discovery clinical trials13 cites · 202488% earned
- 871US12295700B2Systems and methods for estimation of blood flow characteristics using reduced order model5 cites · 202467% earned
- 967US12116640B2Methods for early detection of cancer4 cites · 202454% earned
- 1063US12055541B2System and sensor array6 cites · 202460% earned
- 1158US12511482B1Multi-modal hierarchical tokenization deep neural network2 cites · 202567% earned
- 1254US12088600B1Machine learning system for detecting anomalies in hunt data12 cites · 202488% earned
- 1350US12314385B1Automated generation of anomaly scenarios for testing machine learned anomaly detection mo9 cites · 202587% earned
- 1446US11875879B1Window-based method for determining inherited segments4 cites · 202456% earned
- 1542US11908140B1Method and system for identifying protein domain based on protein three-dimensional struct4 cites · 202482% earned
- 1638US12119090B1Utilizing masked autoencoder generative models to extract microscopy representation autoen4 cites · 202482% earned
- 1733US11894139B1Disease spectrum classification8 cites · 202480% earned
- 1829US12295675B2System for transcribing and performing analysis on patient data2 cites · 202458% earned
- 1925US11923079B1Creating and testing digital bio-markers based on genetic and phenotypic data for therapeu5 cites · 202472% earned
- 2021US12505549B1Microscopy image analyses for disease modeling1 cites · 202550% earned
- 2117US12451216B2Recursive transformers for AI-based protein-protein interaction and drug design1 cites · 202556% earned
- 2213US12424300B1Conditional multicapitate neural networks for AI-based protein and drug design1 cites · 202556% earned
- 238US12046327B1Identity-by-descent relatedness based on focal and reference segments2 cites · 202455% earned
- 244US12243626B2Methods for compression of molecular tagged nucleic acid sequence data2 cites · 202458% earned
- 251US12168800B2Methods and systems for evaluating microsatellite instability status2 cites · 202458% earned
Active· last 5 yrs
The top-scoring G16B patents of the last 5 years
- 199US11352659B2✦ AIMethods of detecting analytes139 cites · 202278% earned
- 296US11447770B1✦ AIMethods and compositions for prime editing nucleotide sequences81 cites · 202278% earned
- 392US12217831B2✦ AIArtificial intelligence-based quality scoring36 cites · 202478% earned
- 488US10984128B1Specially adapted serving networks to automatically provide personalized rapid healthcare 73 cites · 202186% earned
- 583US11501440B2Systems and methods for spatial analysis of analytes using fiducial alignment53 cites · 202185% earned
- 679US11653833B2System and methods for estimation of blood flow characteristics using reduced order model 42 cites · 202181% earned
- 775US11713480B2Materials and methods for localized detection of nucleic acids in a tissue sample33 cites · 202284% earned
- 871US10999285B2Genome sharing47 cites · 202177% earned
- 967US11080607B1Data platform for automated pharmaceutical research using knowledge graph38 cites · 202187% earned
- 1063US12249085B2Sample handling apparatus and image registration methods21 cites · 202382% earned
- 1158US11256995B1System and method for prediction of protein-ligand bioactivity using point-cloud machine l35 cites · 202291% earned
- 1254US11345968B2Methods for computer processing sequence reads to detect molecular residual disease31 cites · 202271% earned
- 1350US11256994B1System and method for prediction of protein-ligand bioactivity and pose propriety31 cites · 202291% earned
- 1446US12016635B2Method and system for image processing to determine blood flow29 cites · 202161% earned
- 1542US11200446B1Single-pass primary analysis29 cites · 202181% earned
- 1638US11145416B1Predicting likelihood and site of metastasis from patient records29 cites · 202183% earned
- 1733US11151982B2Cross-context natural language model generation26 cites · 202174% earned
- 1829US11826106B2Method and system for providing information from a patient-specific model of blood flow31 cites · 202171% earned
- 1925US11887734B2Systems and methods for clinical decision support for lipid-lowering therapies for cardiov20 cites · 202273% earned
- 2021US10891317B1Cohort selection with privacy protection38 cites · 202178% earned
- 2117US11562255B2Cyphergenics-based notarization blockchains19 cites · 202277% earned
- 2213US11357582B1System for transcribing and performing analysis on patient data19 cites · 202279% earned
- 238US11887701B2Non-invasive determination of likely response to anti-inflammatory therapies for cardiovas19 cites · 202385% earned
- 244US11286530B2Methods for simultaneous amplification of target loci23 cites · 202168% earned
- 251US12203142B2Detecting mutations and ploidy in chromosomal segments9 cites · 202460% earned
All-time canon
The defining G16B patents of the whole record
- 199US5766886A✦ AIModified antibody variable domains1,304 cites · 199889% earned
- 296US6453242B1✦ AISelection of sites for targeting by zinc finger proteins and methods of designing zinc fin1,160 cites · 200290% earned
- 392US5525464A✦ AIMethod of sequencing by hybridization of oligonucleotide probes949 cites · 199688% earned
- 488US8795965B2CRISPR-Cas component systems, methods and compositions for sequence manipulation927 cites · 201480% earned
- 583US8871445B2CRISPR-Cas component systems, methods and compositions for sequence manipulation897 cites · 201480% earned
- 679US4704692AComputer based system and method for determining and displaying possible chemical structur804 cites · 198795% earned
- 775US5695940AMethod of sequencing by hybridization of oligonucleotide probes740 cites · 199788% earned
- 871US8906616B2Engineering of systems, methods and optimized guide compositions for sequence manipulation738 cites · 201487% earned
- 967US6763307B2Patient classification721 cites · 200392% earned
- 1063US6344316B1Nucleic acid analysis techniques690 cites · 200288% earned
- 1158US8835358B2Digital counting of individual molecules by stochastic attachment of diverse labels663 cites · 201180% earned
- 1254US5830645AComparative fluorescence hybridization to nucleic acid arrays560 cites · 199888% earned
- 1350US9290808B2Digital counting of individual molecules by stochastic attachment of diverse labels509 cites · 201579% earned
- 1446US8481292B2Increasing confidence of allele calls with molecular counting509 cites · 201286% earned
- 1542US8741606B2Method of tagging using a split DBR481 cites · 201386% earned
- 1638US5871697AMethod and apparatus for identifying, classifying, or quantifying DNA sequences in a sampl476 cites · 199987% earned
- 1733US4881175AComputer based system and method for determining and displaying possible chemical structur474 cites · 198995% earned
- 1829US5980096AComputer-based system, methods and graphical interface for information storage, modeling a463 cites · 199995% earned
- 1925US8315812B2Method and system for patient-specific modeling of blood flow459 cites · 201274% earned
- 2021US7745391B2Human thrombospondin polypeptide455 cites · 200790% earned
- 2117US5795716AComputer-aided visualization and analysis system for sequence evaluation447 cites · 199886% earned
- 2213US6983227B1Virtual models of complex systems436 cites · 200688% earned
- 238US5538897AUse of mass spectrometry fragmentation patterns of peptides to identify amino acid sequenc425 cites · 199692% earned
- 244US5876926AMethod, apparatus and system for verification of human medical data421 cites · 199995% earned
- 251US6090555AScanned image alignment systems and methods403 cites · 200087% earned
Rising· last 2 yrs
Assignees whose newest G16B patents became public in the last 2 years — the current frontier
- 199BROAD INST INC48 patents · 3,267 citations
- 296HEARTFLOW INC100 patents · 3,639 citations
- 392GUARDANT HEALTH INC112 patents · 1,809 citations
- 488CALIFORNIA INST OF TECHN30 patents · 1,693 citations
- 583UNIV CALIFORNIA127 patents · 1,964 citations
- 679NATERA INC71 patents · 1,692 citations
- 77523ANDME INC77 patents · 1,704 citations
- 871UNIV WASHINGTON32 patents · 1,070 citations
- 967ILLUMINA INC151 patents · 893 citations
- 1063PACIFIC BIOSCIENCES CALIFORNIA INC21 patents · 418 citations
- 1158UNIV LELAND STANFORD JUNIOR88 patents · 958 citations
- 125410X GENOMICS INC38 patents · 535 citations
- 1350ALIGN TECHNOLOGY INC18 patents · 295 citations
- 1446SEVEN BRIDGES GENOMICS INC61 patents · 379 citations
- 1542HARVARD COLLEGE35 patents · 379 citations
- 1638PERSONALIS INC37 patents · 324 citations
- 1733BESPOKE INC15 patents · 204 citations
- 1829IBM214 patents · 944 citations
- 1925BECTON DICKINSON CO20 patents · 196 citations
- 2021BOSTONGENE CORP31 patents · 142 citations
- 2117ABBOTT DIABETES CARE INC16 patents · 234 citations
- 2213GENOMIC HEALTH INC12 patents · 207 citations
- 238VERACYTE INC10 patents · 139 citations
- 244BRIGHAM & WOMENS HOSPITAL INC12 patents · 94 citations
- 251UNIV TEXAS24 patents · 248 citations
Active· last 5 yrs
Sustained G16B output across the last 5 years
- 199BROAD INST INC48 patents · 3,267 citations
- 296HEARTFLOW INC100 patents · 3,639 citations
- 392GUARDANT HEALTH INC112 patents · 1,809 citations
- 488CALIFORNIA INST OF TECHN30 patents · 1,693 citations
- 583UNIV CALIFORNIA127 patents · 1,964 citations
- 679NATERA INC71 patents · 1,692 citations
- 77523ANDME INC77 patents · 1,704 citations
- 871MASSACHUSETTS INST TECHNOLOGY31 patents · 729 citations
- 967UNIV WASHINGTON32 patents · 1,070 citations
- 1063ILLUMINA INC151 patents · 893 citations
- 1158PACIFIC BIOSCIENCES CALIFORNIA INC21 patents · 418 citations
- 1254UNIV LELAND STANFORD JUNIOR88 patents · 958 citations
- 135010X GENOMICS INC38 patents · 535 citations
- 1446ALIGN TECHNOLOGY INC18 patents · 295 citations
- 1542EMC CORP11 patents · 255 citations
- 1638SEVEN BRIDGES GENOMICS INC61 patents · 379 citations
- 1733HARVARD COLLEGE35 patents · 379 citations
- 1829PERSONALIS INC37 patents · 324 citations
- 1925BESPOKE INC15 patents · 204 citations
- 2021UNIV HONG KONG CHINESE63 patents · 433 citations
- 2117IBM214 patents · 944 citations
- 2213ZYMERGEN INC20 patents · 261 citations
- 238BECTON DICKINSON CO20 patents · 196 citations
- 244CARIS MPI INC16 patents · 136 citations
- 251BOSTONGENE CORP31 patents · 142 citations
All-time canon
All-time PatentIndex Score in G16B
- 199TAYLOR CHARLES A13 patents · 2,140 citations
- 296BROAD INST INC48 patents · 3,267 citations
- 392DHARMACON INC78 patents · 4,683 citations
- 488AFFYMETRIX INC80 patents · 5,637 citations
- 583CELLULAR RES INC14 patents · 1,518 citations
- 679POPULATION GENETICS TECH LTD7 patents · 1,825 citations
- 775HEARTFLOW INC100 patents · 3,639 citations
- 871GUARDANT HEALTH INC112 patents · 1,809 citations
- 967CALIFORNIA INST OF TECHN30 patents · 1,693 citations
- 1063KEYGENE NV21 patents · 2,340 citations
- 1158MAXYGEN INC11 patents · 2,028 citations
- 1254EXPANSE NETWORKS INC9 patents · 562 citations
- 1350KENEDY ANDREW ALEXANDER13 patents · 683 citations
- 1446DIMENSIONAL PHARM INC5 patents · 938 citations
- 1542CURAGEN CORP13 patents · 1,297 citations
- 1638EXPANSE BIOINFORMATICS INC5 patents · 227 citations
- 1733UNIV CALIFORNIA127 patents · 1,964 citations
- 1829INCYTE PHARMA INC12 patents · 1,684 citations
- 1925ROSETTA INPHARMATICS INC11 patents · 1,313 citations
- 2021NATERA INC71 patents · 1,692 citations
- 211723ANDME INC77 patents · 1,704 citations
- 2213MASSACHUSETTS INST TECHNOLOGY31 patents · 729 citations
- 238SENOMYX INC10 patents · 424 citations
- 244SANGAMO BIOSCIENCES INC11 patents · 1,613 citations
- 251UNIV WASHINGTON32 patents · 1,070 citations
90–99 field-defining50–89 strong<50 emergingearned by citationsfrom family breadth