Inventor · disambiguated record
Nathaniel David
Also filed as: DAVID NATHANIEL · DAVID NATHANIEL E · DAVID NATHANIEL EAMES
44 granted patents·35 pending applications·427 citations·filing 2001–2025
98Inventor score
Files withUNITY BIOTECHNOLOGY INC20BUCK INST RES AGING16KYTHERA BIOPHARMACEUTICALS INC11DAVID NATHANIEL E6ALLERGAN SALES LLC4
Top patents by PatentIndex Score
79 records- 0198US10010546B2Treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2017·Granted Jul 3, 2018·23 cites·11 claims
- 0297US10195213B2Chemical entities that kill senescent cells for use in treating age-related diseaseUNITY BIOTECHNOLOGY INC·Filed 2016·Granted Feb 5, 2019·15 cites·8 claims
- 0397US9849128B2Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cellsBUCK INST RES AGING·Filed 2017·Granted Dec 26, 2017·24 cites·15 claims
- 0497US6872250B2Microvolume crystallization method employing multiple lumensSYRRX INC·Filed 2002·Granted Mar 29, 2005·109 cites·32 claims
- 0596US9993472B2Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2BUCK INST RES AGING·Filed 2015·Granted Jun 12, 2018·20 cites·7 claims
- 0696US9980962B2Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary diseaseBUCK INST RES AGING·Filed 2017·Granted May 29, 2018·6 cites·8 claims
- 0796US9855266B2Treatment for osteoarthritis by intra-articular administration of a cis-imidazolineBUCK INST RES AGING·Filed 2017·Granted Jan 2, 2018·12 cites·14 claims
- 0895US10328073B2Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cellsUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Jun 25, 2019·9 cites·16 claims
- 0995US10130628B2Treatment of joint painUNITY BIOTECHNOLOGY INC·Filed 2017·Granted Nov 20, 2018·6 cites·8 claims
- 1095US9636349B2Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICALS INC·Filed 2015·Granted May 2, 2017·14 cites·7 claims
- 1195US8242294B2Synthetic bile acid compositions and methodsMORIARTY ROBERT M·Filed 2009·Granted Aug 14, 2012·23 cites·2 claims
- 1294US10478432B2Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eyeBUCK INST RES AGING·Filed 2018·Granted Nov 19, 2019·7 cites·18 claims
- 1394US9050349B2Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICALS INC·Filed 2013·Granted Jun 9, 2015·15 cites·18 claims
- 1494US8461140B2Synthetic bile acid compositions and methodsMORIARTY ROBERT M·Filed 2012·Granted Jun 11, 2013·16 cites·6 claims
- 1593US8546367B2Synthetic bile acid compositions and methodsMORIARTY ROBERT M·Filed 2012·Granted Oct 1, 2013·15 cites·16 claims
- 1692US10517866B2Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitorUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Dec 31, 2019·5 cites·15 claims
- 1792US10258618B2Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimenBUCK INST RES AGING·Filed 2018·Granted Apr 16, 2019·5 cites·17 claims
- 1892US9987291B2Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICALS INC·Filed 2017·Granted Jun 5, 2018·7 cites·15 claims
- 1991US10328058B2Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaquesMAYO FOUND MEDICAL EDUCATION & RES·Filed 2017·Granted Jun 25, 2019·5 cites·12 claims
- 2091US10213426B2Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell populationBUCK INST RES AGING·Filed 2017·Granted Feb 26, 2019·5 cites·13 claims
- 2190US11351167B2Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissueBUCK INST RES AGING·Filed 2019·Granted Jun 7, 2022·1 cites·14 claims
- 2290US10478433B2Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision lossUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Nov 19, 2019·4 cites·20 claims
- 2390US10413542B2Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinaseBUCK INST RES AGING·Filed 2018·Granted Sep 17, 2019·4 cites·12 claims
- 2490US8883770B2Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICAL INC·Filed 2013·Granted Nov 11, 2014·16 cites·1 claims
- 2589US10426788B2Chemical entities that kill senescent cells for use in treating age-related diseaseUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Oct 1, 2019·2 cites·8 claims
- 2689US9683008B2Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICALS INC·Filed 2015·Granted Jun 20, 2017·2 cites·2 claims
- 2788US10550378B2Composition comprising a gene vector that selectively depletes P16 positive senescent cellsUNITY BIOTECHNOLOGY INC·Filed 2019·Granted Feb 4, 2020·2 cites·10 claims
- 2888US10378002B2Replication conditional virus that specifically kills senescent cellsUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Aug 13, 2019·2 cites·8 claims
- 2986US11129838B2Methods of inhibiting pathological angiogenesisUNITY BIOTECHNOLOGY INC·Filed 2020·Granted Sep 28, 2021·2 cites·28 claims
- 3086US9522155B2Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICALS INC·Filed 2014·Granted Dec 20, 2016·5 cites·9 claims
- 3184US10588916B2Technology to inhibit vascular changes that lead to vision loss in the eyeUNITY BIOTECHNOLOGY INC·Filed 2018·Granted Mar 17, 2020·2 cites·5 claims
- 3284US10144757B2Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICALS INC·Filed 2017·Granted Dec 4, 2018·1 cites·7 claims
- 3384US9127036B2Synthetic bile acid compositions and methodsMORIARTY ROBERT M·Filed 2010·Granted Sep 8, 2015·2 cites·2 claims
- 3482US12285427B2Treatment of a senescence-associated ocular disease or disorder using a Bcl-xL selective inhibitorBUCK INST RES AGING·Filed 2023·Granted Apr 29, 2025·0 cites·4 claims
- 3580US11202786B2Synthetic bile acid compositions and methodsALLERGAN SALES LLC·Filed 2019·Granted Dec 21, 2021·0 cites·8 claims
- 3679US11980616B2Treating liver disease by selectively eliminating senescent cellsBUCK INST RES AGING·Filed 2020·Granted May 14, 2024·0 cites·23 claims
- 3779US10434107B2Synthetic bile acid compositions and methodsALLERGAN SALES LLC·Filed 2018·Granted Oct 8, 2019·1 cites·8 claims
- 3879US6719840B2In situ crystal growth and crystallizationSYRRX INC·Filed 2001·Granted Apr 13, 2004·35 cites·38 claims
- 3979US2019343832A1Therapy for removing senescent cells and treating senescence-associated disease using an mdm2 inhibitorUNITY BIOTECHNOLOGY INC·Filed 2019·Application pending·0 cites
- 4078US11963957B2Treating cardiovascular disease by selectively eliminating senescent cellsBUCK INST RES AGING·Filed 2020·Granted Apr 23, 2024·0 cites·24 claims
- 4178US11026955B2Synthetic bile acid compositions and methodsALLERGAN SALES LLC·Filed 2019·Granted Jun 8, 2021·0 cites·8 claims
- 4278US9949986B2Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICALS INC·Filed 2016·Granted Apr 24, 2018·1 cites·7 claims
- 4377US2021030752A1Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissueBUCK INST RES AGING·Filed 2020·Application pending·0 cites
- 4473US2020370029A1Composition comprising a gene vector that selectively depletes p16 positive senescent cellsUNITY BIOTECHNOLOGY INC·Filed 2019·Application pending·0 cites
- 4572US2022096466A1Treatment of parkinson's disease and other conditions caused or mediated by senescent astrocytes using small molecule senolytic agentsBUCK INSTITUTE FOR RES AND AGING·Filed 2021·Application pending·0 cites
- 4672US2025368711A1Compositions and methods for treating meibomian gland dysfunctionCAVALRY BIOSCIENCES INC·Filed 2025·Application pending·0 cites
- 4771US2020069703A1Chemical entities that kill senescent cells for use in treating age-related diseaseUNITY BIOTECHNOLOGY INC·Filed 2019·Application pending·0 cites
- 4871US2019127415A1Synthetic bile acid compositions and methodsKYTHERA BIOPHARMACEUTICALS INC·Filed 2018·Application pending·0 cites
- 4971US2019175623A1Chemical compounds for treating atherosclerosis by stabilizing atherosclerotic plaques or delaying atherogenesisBUCK INST RES AGING·Filed 2018·Application pending·0 cites
- 5070US11865123B2Methods of inhibiting pathological angiogenesisUNITY BIOTECHNOLOGY INC·Filed 2021·Granted Jan 9, 2024·0 cites·6 claims
Showing the top 50 of 79 patent records by PatentIndex Score.
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Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →