Inventor · disambiguated record
Bruce M. Spiegelman
Also filed as: FORMAN BARRY M · SPIEGELMAN BRUCE · SPIEGELMAN BRUCE M
42 granted patents·14 pending applications·731 citations·filing 1988–2023
98Inventor score
Files withDANA FARBER CANCER INST INC36SPIEGELMAN BRUCE M8MILLENNIUM PHARM INC2SALK INST FOR BIOLOGICAL STUDI2BETH ISRAEL HOSPITAL1
Top patents by PatentIndex Score
56 records- 0195US6015558ATreatment of insulin resistance in obesity linked type II diabetes using antagonists to TNF-α functionDANA FARBER CANCER INST INC·Filed 1998·Granted Jan 18, 2000·134 cites·5 claims
- 0295US5730975ATreatment of insulin resistance in obesity linked type II diabetes using antagonist to TNF-alpha functionDANA FARBER CANCER INST INC·Filed 1994·Granted Mar 24, 1998·148 cites·13 claims
- 0392US7354738B2PGC-1β, a novel PGC-1 homologue and uses thereforDANA FARBER CANCER INST INC·Filed 2006·Granted Apr 8, 2008·19 cites·5 claims
- 0489US6242196B1Methods and pharmaceutical compositions for inhibiting tumor cell growthDANA FARBER CANCER INST INC·Filed 1997·Granted Jun 5, 2001·117 cites·35 claims
- 0588US7691578B2Methods and compositions for treating obesityDANA FARBER CANCER INST INC·Filed 2005·Granted Apr 6, 2010·11 cites·41 claims
- 0684US10328131B2Compositions and methods for regulating pancreatic beta cell function using adipsinDANA FARBER CANCER INST INC·Filed 2015·Granted Jun 25, 2019·2 cites·7 claims
- 0783US7091006B2PGC-1β, a novel PGC-1 homologue and uses thereforDANA FARBER CANCER INST INC·Filed 2002·Granted Aug 15, 2006·14 cites·8 claims
- 0882US7250283B2PGC-1 isoforms and uses thereforDANA FARBER CANCER INST INC·Filed 2002·Granted Jul 31, 2007·16 cites·13 claims
- 0981US6908987B2PCG-1, a novel brown fat PPARγ coactivatorDANA FARBER CANCER INST INC·Filed 2003·Granted Jun 21, 2005·12 cites·9 claims
- 1080US8969519B2Compositions and methods for brown fat induction and activity using FNDC5SPIEGELMAN BRUCE M·Filed 2012·Granted Mar 3, 2015·3 cites·20 claims
- 1176US6033656AMethod of preventing or alleviating mammalian obesitySUMITOMO CHEMICAL CO·Filed 1999·Granted Mar 7, 2000·53 cites·18 claims
- 1276US5223425ADNA encoding human adipsin with complement D activityBETH ISRAEL HOSPITAL·Filed 1988·Granted Jun 29, 1993·24 cites·9 claims
- 1375US6166192APGC-1, a novel brown fat PPARγ coactivatorDANA FARBER CANCER INST INC·Filed 1998·Granted Dec 26, 2000·36 cites·14 claims
- 1473US11766471B2Compositions and methods for induced brown fat differentiationDANA FARBER CANCER INST INC·Filed 2019·Granted Sep 26, 2023·0 cites·16 claims
- 1572US10093705B2Compositions and methods for brown fat induction and activity using FNDC5SPIEGELMAN BRUCE M·Filed 2012·Granted Oct 9, 2018·1 cites·20 claims
- 1672US5137734AAngiogenic monoglyceridesDANA FARBER CANCER INST INC·Filed 1989·Granted Aug 11, 1992·55 cites·7 claims
- 1771US6552055B2Methods and pharmaceutical compositions for inhibiting tumor cell growthDANA FARBER CANCER INST INC·Filed 1997·Granted Apr 22, 2003·44 cites·4 claims
- 1870US8889639B2Compositions and methods for modulating PGC-1β to treat lipid-related diseases and disordersSPIEGELMAN BRUCE M·Filed 2005·Granted Nov 18, 2014·1 cites·38 claims
- 1970US6525178B2PGC-1, a novel brown fat PPARgamma coactivatorDANA FARBER CANCER INST INC·Filed 2001·Granted Feb 25, 2003·3 cites·12 claims
- 2069US9074012B2Molecular control of brown fat differentiation and energy expenditureSEALE PATRICK·Filed 2007·Granted Jul 7, 2015·2 cites·8 claims
- 2168US11331379B2Compositions and methods for regulating pancreatic beta cell function using adipsinDANA FARBER CANCER INST INC·Filed 2019·Granted May 17, 2022·0 cites·20 claims
- 2268US10286042B2Methods for the treatment of neurological disorders and diseases using FNDC5DANA FARBER CANCER INST INC·Filed 2014·Granted May 14, 2019·1 cites·12 claims
- 2368US2022062389A1Methods for the identification, assessment, prevention, and treatment of neurological disorders and diseases using fndc5DANA FARBER CANCER INST INC·Filed 2021·Application pending·0 cites
- 2467US11129879B2Methods for the treatment of neurological disorders and diseases using FNDC5DANA FARBER CANCER INST INC·Filed 2019·Granted Sep 28, 2021·0 cites·5 claims
- 2567US6872391B2PGC-1, a novel brown fat PPARγ coactivatorDANA FARBER CANCER INST INC·Filed 2002·Granted Mar 29, 2005·2 cites·6 claims
- 2667US2025161413A1Methods for decreasing pathologic alpha-synuclein using agents that modulate fndc5 or biologically active fragments thereofDANA FARBER CANCER INST INC·Filed 2023·Application pending·0 cites
- 2766US7947652B2Compositions and methods for modulating PGC-1α to treat huntington's diseaseDANA FARBER CANCER INST INC·Filed 2005·Granted May 24, 2011·1 cites·8 claims
- 2865US9181315B2Compositions and methods for induced brown fat differentiationSPIEGELMAN BRUCE M·Filed 2010·Granted Nov 10, 2015·1 cites·5 claims
- 2965US6974671B1Methods for indentifying compounds that modulate gluconeogenesis through the binding of CREB to the PGC-1 promoterSALK INST FOR BIOLOGICAL STUDI·Filed 2002·Granted Dec 13, 2005·2 cites·3 claims
- 3064US11098092B2Compositions and methods for brown fat induction and activity using FNDC5DANA FARBER CANCER INST INC·Filed 2018·Granted Aug 24, 2021·0 cites·12 claims
- 3164US8105774B2PGC-1β, PGC-1 homologue and uses thereforSPIEGELMAN BRUCE M·Filed 2008·Granted Jan 31, 2012·0 cites·9 claims
- 3263US2022193193A1Methods for identification, assessment, prevention, and treatment of metabolic disorders using slit2DANA FARBER CANCER INST INC·Filed 2022·Application pending·0 cites
- 3360US7635708B2Methods and pharmaceutical compositions for inhibiting tumor cell growthDANA FARBER CANCER INST INC·Filed 2002·Granted Dec 22, 2009·1 cites·27 claims
- 3458US2003045470A1Methods and compositions for modulating gluconeogenesis using PGC-1DANA FARBER CANCER INST INC·Filed 2002·Application pending·0 cites
- 3555US8445233B2PGC-1β, a novel PGC-1 homologue and uses thereforSPIEGELMAN BRUCE M·Filed 2011·Granted May 21, 2013·0 cites·10 claims
- 3655US2005100940A1Novel FDRG protein and nucleic acid molecules and uses thereforMILLENNIUM PHARM INC·Filed 2004·Application pending·0 cites
- 3754US12194080B2Methods for identification, assessment, prevention, and treatment of metabolic disorders using PM20D1 and N-lipidated amino acidsDANA FARBER CANCER INST INC·Filed 2016·Granted Jan 14, 2025·0 cites·8 claims
- 3853US2009098569A1Novel PGC-1 Isoforms and Uses ThereforDANA FARBER CANCER INST INC·Filed 2007·Application pending·0 cites
- 3952US2008248475A1Methods and Compositions for Modulating Gluconeogenesis Using PGC-1DANA FARBER CANCER INST INC·Filed 2007·Application pending·0 cites
- 4051US11365177B2Chemical uncouplers of respiration and methods of use thereofDANA FARBER CANCER INST INC·Filed 2018·Granted Jun 21, 2022·0 cites·19 claims
- 4150US2006035849A1Methods and composition for modulating type I muscle formation using pgc-1 alphaDANAFARBER CANCER INST INC·Filed 2003·Application pending·0 cites
- 4249US11291706B2Methods for identification, assessment, prevention, and treatment of metabolic disorders using Slit2DANA FARBER CANCER INST INC·Filed 2016·Granted Apr 5, 2022·0 cites·4 claims
- 4349US5476926AAdipocyte-specific DNA sequences and use thereof in the production of transgenic animals exhibiting altered fat tissue metabolismFiled 1991·Granted Dec 19, 1995·16 cites·7 claims
- 4449US2004077566A9Methods and compositions for the treatment and diagnosis of body weight disordersMILLENNIUM PHARM INC·Filed 2002·Application pending·0 cites
- 4548US7371529B2Methods and compositions for modulating gluconeogenesis using PGC-1DANA FARBER CANCER INST INC·Filed 2005·Granted May 13, 2008·0 cites·8 claims
- 4648US2003099994A1Novel FDRG protein and nucleic acid molecules and uses thereforMILLENNIUM PHARAMCEUTICALS INC·Filed 2002·Application pending·0 cites
- 4746US10717992B2Compositions and methods for regulating thermogenesis and muscle inflammation using metrnl and metrnDANA FARBER CANCER INST INC·Filed 2014·Granted Jul 21, 2020·0 cites·9 claims
- 4846US2016175401A1Compoitions and methods for modulating thermogenesis using pth-related and egf-related compoundsDANA FARBER CANCER INST INC·Filed 2014·Application pending·0 cites
- 4945US2012167240A1Compositions and Methods for Modulating PGC-1Alpha to Treat Neurological Diseases and DisordersLIN JIANDIE·Filed 2011·Application pending·0 cites
- 5044US2016095905A1Compositions and Methods for Induced Brown Fat DifferentiationDANA FARBER CANCER INST INC·Filed 2015·Application pending·0 cites
Showing the top 50 of 56 patent records by PatentIndex Score.
Join the waitlist — get patent alerts
Get an alert when Bruce M. Spiegelman files or is granted a new patent.
We store only your email — no account needed. See our privacy policy.
Identity basis: PatentsView inventor disambiguation (2025Q4-odp release). How scoring works →