Assignee
MANOHARAN MUTHIAH
US·31 granted patents·18 pending applications·2,024 citations·filing 2003–2013
Top patents by PatentIndex Score
49 records- 0199US8106022B2Carbohydrate conjugates as delivery agents for oligonucleotidesMANOHARAN MUTHIAH·Filed 2008·Granted Jan 31, 2012·588 cites·21 claims
- 0298US9186325B2Lipids and compositions for the delivery of therapeuticsMANOHARAN MUTHIAH·Filed 2009·Granted Nov 17, 2015·100 cites·19 claims
- 0398US9012498B2Biodegradable lipids for the delivery of active agentsMANOHARAN MUTHIAH·Filed 2011·Granted Apr 21, 2015·104 cites·41 claims
- 0498US8999351B2Lipids and compositions for the delivery of therapeuticsMANOHARAN MUTHIAH·Filed 2009·Granted Apr 7, 2015·102 cites·15 claims
- 0598US8883202B2Lipid compositionsMANOHARAN MUTHIAH·Filed 2010·Granted Nov 11, 2014·104 cites·22 claims
- 0698US8642076B2Lipid containing formulationsMANOHARAN MUTHIAH·Filed 2011·Granted Feb 4, 2014·155 cites·28 claims
- 0798US8575123B2Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic componentsMANOHARAN MUTHIAH·Filed 2009·Granted Nov 5, 2013·82 cites·39 claims
- 0898US8450467B2Carbohydrate conjugates as delivery agents for oligonucleotidesMANOHARAN MUTHIAH·Filed 2011·Granted May 28, 2013·227 cites·21 claims
- 0998US8404862B2Ligand-conjugated monomersMANOHARAN MUTHIAH·Filed 2009·Granted Mar 26, 2013·84 cites·40 claims
- 1097US8927513B25′ phosphate mimicsMANOHARAN MUTHIAH·Filed 2010·Granted Jan 6, 2015·108 cites·14 claims
- 1197US8722082B2Lipids and compositions for the delivery of therapeuticsMANOHARAN MUTHIAH·Filed 2009·Granted May 13, 2014·44 cites·25 claims
- 1297US8507455B2Folate conjugatesMANOHARAN MUTHIAH·Filed 2008·Granted Aug 13, 2013·32 cites·14 claims
- 1397US8110674B2Therapeutic compositionsMANOHARAN MUTHIAH·Filed 2004·Granted Feb 7, 2012·81 cites·39 claims
- 1496US9687550B2Compositions for nucleic acid deliveryMANOHARAN MUTHIAH·Filed 2010·Granted Jun 27, 2017·21 cites·5 claims
- 1596US8507661B2Modified iRNA agentsMANOHARAN MUTHIAH·Filed 2010·Granted Aug 13, 2013·25 cites·48 claims
- 1695US9220683B2Lipids and compositions for the delivery of therapeuticsMANOHARAN MUTHIAH·Filed 2009·Granted Dec 29, 2015·28 cites·17 claims
- 1795US8975389B2Nucleic acid chemical modificationsMANOHARAN MUTHIAH·Filed 2010·Granted Mar 10, 2015·31 cites·23 claims
- 1894US8426377B2iRNA agents with biocleavable tethersMANOHARAN MUTHIAH·Filed 2010·Granted Apr 23, 2013·10 cites·20 claims
- 1992US8962580B2Chemical modifications of monomers and oligonucleotides with cycloadditionMANOHARAN MUTHIAH·Filed 2009·Granted Feb 24, 2015·26 cites·11 claims
- 2092US8420799B2Therapeutic compositionsMANOHARAN MUTHIAH·Filed 2010·Granted Apr 16, 2013·11 cites·13 claims
- 2190US8754201B2Therapeutic compositionsMANOHARAN MUTHIAH·Filed 2010·Granted Jun 17, 2014·8 cites·26 claims
- 2289US8431693B2Process for desilylation of oligonucleotidesMANOHARAN MUTHIAH·Filed 2011·Granted Apr 30, 2013·15 cites·28 claims
- 2388US9725479B25′-end derivativesMANOHARAN MUTHIAH·Filed 2011·Granted Aug 8, 2017·12 cites·15 claims
- 2487US9198972B2Monomers and oligonucleotides comprising cycloaddition adduct(s)MANOHARAN MUTHIAH·Filed 2011·Granted Dec 1, 2015·10 cites·8 claims
- 2585US9512164B2Oligonucleotide end capsMANOHARAN MUTHIAH·Filed 2010·Granted Dec 6, 2016·4 cites·13 claims
- 2683US8445665B2Therapeutic compositionsMANOHARAN MUTHIAH·Filed 2010·Granted May 21, 2013·3 cites·14 claims
- 2781US9254327B2Methods and compositions for delivery of active agentsMANOHARAN MUTHIAH·Filed 2011·Granted Feb 9, 2016·2 cites·20 claims
- 2880US10913767B2Oligonucleotides comprising acyclic and abasic nucleosides and analogsMANOHARAN MUTHIAH·Filed 2011·Granted Feb 9, 2021·4 cites·25 claims
- 2980US8470988B2Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moietyMANOHARAN MUTHIAH·Filed 2009·Granted Jun 25, 2013·3 cites·30 claims
- 3067US8063198B2Processes and reagents for desilylation of oligonucleotidesMANOHARAN MUTHIAH·Filed 2008·Granted Nov 22, 2011·0 cites·39 claims
- 3163US2012095075A1Novel lipids and compositions for the delivery of therapeuticsMANOHARAN MUTHIAH·Filed 2011·Application pending·0 cites
- 3262US2007105803A1Methods and compositions for treating neurological diseaseMANOHARAN MUTHIAH·Filed 2006·Application pending·0 cites
- 3362US2013261166A1Methods and compositions for treating neurological diseaseMANOHARAN MUTHIAH·Filed 2013·Application pending·0 cites
- 3461US8058448B2Processes and reagents for sulfurization of oligonucleotidesMANOHARAN MUTHIAH·Filed 2009·Granted Nov 15, 2011·0 cites·18 claims
- 3561US2012107272A1Synthetic methods and derivatives of triphosphate oligonucleotidesMANOHARAN MUTHIAH·Filed 2009·Application pending·0 cites
- 3661US2004266706A1Cross-linked oligomeric compounds and their use in gene modulationMANOHARAN MUTHIAH·Filed 2003·Application pending·0 cites
- 3759US2013323269A1Methods and compositions for delivery of active agentsMANOHARAN MUTHIAH·Filed 2011·Application pending·0 cites
- 3857US2005267300A1Processes and reagents for oligonucleotide synthesis and purificationMANOHARAN MUTHIAH·Filed 2005·Application pending·0 cites
- 3957US2011251257A1Methods and compositions for treating neurological diseaseMANOHARAN MUTHIAH·Filed 2010·Application pending·0 cites
- 4056US2011027882A1Methods and Compositions for Treating Neurological DiseaseMANOHARAN MUTHIAH·Filed 2010·Application pending·0 cites
- 4154US2005233342A1Methods of preventing off-target gene silencingMANOHARAN MUTHIAH·Filed 2004·Application pending·0 cites
- 4253US2007123702A1Oligonucleotdies having A-DNA form and B-DNA form conformational geometryMANOHARAN MUTHIAH·Filed 2005·Application pending·0 cites
- 4353US2011313144A1iRNA Agents Targeting CCR5 Expressing Cells And Uses ThereofMANOHARAN MUTHIAH·Filed 2011·Application pending·0 cites
- 4453US2007179100A1Protected monomersMANOHARAN MUTHIAH·Filed 2004·Application pending·0 cites
- 4551US2011118340A1Delivery of rnai constructs to oligodendrocytesMANOHARAN MUTHIAH·Filed 2009·Application pending·0 cites
- 4647US2013202652A1Methods and compositions for delivery of active agentsMANOHARAN MUTHIAH·Filed 2011·Application pending·0 cites
- 4742US2013156845A1Lipid formulated single stranded rnaMANOHARAN MUTHIAH·Filed 2011·Application pending·0 cites
- 4840US2013236968A1Multifunctional copolymers for nucleic acid deliveryMANOHARAN MUTHIAH·Filed 2011·Application pending·0 cites
- 4938US2011282044A1Process for synthesizing oligonucleotide phosphate derivativesMANOHARAN MUTHIAH·Filed 2010·Application pending·0 cites
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