Assignee
ABBVIE INC
US·482 granted patents·582 pending applications·3,910 citations·filing 2008–2025
Top patents by PatentIndex Score
1,064 records- 0198US11787815B1Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Oct 17, 2023·8 cites·10 claims
- 0298US11780847B1Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1- carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Oct 10, 2023·7 cites·8 claims
- 0398US11718627B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Aug 8, 2023·9 cites·30 claims
- 0498US11535625B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2022·Granted Dec 27, 2022·19 cites·20 claims
- 0598US11535624B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-α]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2022·Granted Dec 27, 2022·19 cites·5 claims
- 0698US11535626B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1 carboxamide and solid state forms thereofABBVIE INC·Filed 2022·Granted Dec 27, 2022·18 cites·20 claims
- 0798US11524964B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2022·Granted Dec 13, 2022·21 cites·10 claims
- 0898US11512092B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2022·Granted Nov 29, 2022·21 cites·22 claims
- 0998US11198697B1Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2021·Granted Dec 14, 2021·29 cites·30 claims
- 1098US11186584B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2021·Granted Nov 30, 2021·28 cites·23 claims
- 1198US10995095B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carb oxamide and solid state forms thereofABBVIE INC·Filed 2019·Granted May 4, 2021·28 cites·9 claims
- 1298US10981924B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2020·Granted Apr 20, 2021·33 cites·25 claims
- 1398US10981923B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[l,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2020·Granted Apr 20, 2021·32 cites·30 claims
- 1498US10730883B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2020·Granted Aug 4, 2020·35 cites·5 claims
- 1598US10597400B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carb oxamide and solid state forms thereofABBVIE INC·Filed 2019·Granted Mar 24, 2020·36 cites·24 claims
- 1698US10550126B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2018·Granted Feb 4, 2020·37 cites·9 claims
- 1798US10519164B2Processes for the preparation of (3S,4R)-3,ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2019·Granted Dec 31, 2019·35 cites·11 claims
- 1898US10344036B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-#a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-#carboxamide and solid state forms thereofABBVIE INC·Filed 2018·Granted Jul 9, 2019·35 cites·30 claims
- 1998US10202394B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2018·Granted Feb 12, 2019·37 cites·30 claims
- 2098US10202393B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-α]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2018·Granted Feb 12, 2019·37 cites·30 claims
- 2198US10017517B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-α]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluorethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2018·Granted Jul 10, 2018·41 cites·30 claims
- 2298US9963459B1Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-alpla]pyrrolo[2,3-e]-pyrazin-8-YL)-N-(2,2,2-Trifluoroethyl)pyrrol and solid state forms thereofABBVIE INC·Filed 2017·Granted May 8, 2018·42 cites·30 claims
- 2398US9951080B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-alpha]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2017·Granted Apr 24, 2018·41 cites·30 claims
- 2498US9359434B2Cell culture methods to reduce acidic speciesABBVIE INC·Filed 2015·Granted Jun 7, 2016·35 cites·30 claims
- 2598US9284371B2Methods of producing adalimumabABBVIE INC·Filed 2015·Granted Mar 15, 2016·29 cites·30 claims
- 2698US9241873B2Medicine container, method of assembling the container, and method of dispensing the medicine from the containerABBVIE INC·Filed 2014·Granted Jan 26, 2016·32 cites·20 claims
- 2797US12091415B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Sep 17, 2024·3 cites·3 claims
- 2897US12077545B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Sep 3, 2024·2 cites·11 claims
- 2997US11773105B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]- pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Oct 3, 2023·7 cites·30 claims
- 3097US11767326B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Sep 26, 2023·7 cites·24 claims
- 3197US11680069B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2022·Granted Jun 20, 2023·6 cites·30 claims
- 3297US11661425B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2022·Granted May 30, 2023·9 cites·30 claims
- 3397USRE47221ETricyclic compoundsABBVIE INC·Filed 2017·Granted Feb 5, 2019·42 cites·14 claims
- 3497US9365579B2Tricyclic compoundsABBVIE INC·Filed 2015·Granted Jun 14, 2016·50 cites·15 claims
- 3597US9365645B1Methods for controlling the galactosylation profile of recombinantly-expressed proteinsABBVIE INC·Filed 2016·Granted Jun 14, 2016·18 cites·30 claims
- 3697US9334319B2Low acidic species compositionsABBVIE INC·Filed 2013·Granted May 10, 2016·29 cites·61 claims
- 3797US9290568B2Methods to control protein heterogeneityABBVIE INC·Filed 2015·Granted Mar 22, 2016·19 cites·30 claims
- 3897US9266949B2Low acidic species compositions and methods for producing and using the sameABBVIE INC·Filed 2014·Granted Feb 23, 2016·25 cites·30 claims
- 3997US9234033B2Methods to control protein heterogeneityABBVIE INC·Filed 2015·Granted Jan 12, 2016·17 cites·30 claims
- 4097US9200070B2Low acidic species compositions and methods for producing and using the sameABBVIE INC·Filed 2015·Granted Dec 1, 2015·21 cites·30 claims
- 4197US9200069B2Low acidic species compositions and methods for producing and using the sameABBVIE INC·Filed 2015·Granted Dec 1, 2015·18 cites·30 claims
- 4297US9174982B2Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseasesABBVIE INC·Filed 2013·Granted Nov 3, 2015·38 cites·7 claims
- 4397US9150645B2Cell culture methods to reduce acidic speciesABBVIE INC·Filed 2013·Granted Oct 6, 2015·40 cites·55 claims
- 4497US9085618B2Low acidic species compositions and methods for producing and using the sameABBVIE INC·Filed 2013·Granted Jul 21, 2015·38 cites·30 claims
- 4597US8906646B2Fed-batch method of making human anti-TNF-alpha antibodyABBVIE INC·Filed 2014·Granted Dec 9, 2014·44 cites·28 claims
- 4697US8686136B2Apoptosis promotersABBVIE INC·Filed 2012·Granted Apr 1, 2014·20 cites·2 claims
- 4796US11976077B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-α]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms therofABBVIE INC·Filed 2023·Granted May 7, 2024·6 cites·24 claims
- 4896US11795175B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Oct 24, 2023·8 cites·24 claims
- 4996US11780848B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1- carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Oct 10, 2023·7 cites·18 claims
- 5096US11773106B2Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereofABBVIE INC·Filed 2023·Granted Oct 3, 2023·7 cites·15 claims
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