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FR8 patents

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US7875436B2Jan 25, 2011

Peptide substrates recognizable by a botulinum toxin A, BoNT/A and the use thereof

PHARMALEADS8 citations82
US9388129B2Jul 12, 2016

Mixed inhibitors of aminopeptidase N and neprilysin

PHARMALEADS2 citations60
US11648231B2May 16, 2023

Amino acid derivatives containing a disulfanyl group in the form of an NEP and APN inhibitor for the prevention and treatment of trigeminal nerve pain

PHARMALEADS1 citations56
US11090317B2Aug 17, 2021

Aminophosphinic derivatives for preventing and treating eye inflammation

PHARMALEADS1 citations50
US10131681B2Nov 20, 2018

Aminophosphinic derivatives that can be used in the treatment of pain

PHARMALEADS1 citations49
US12391710B2Aug 19, 2025

Method for the industrial preparation of the disodium salt of ((2S)-3-([1,1′-biphenyl]-4-yl-2-((hydroxy((1R)-1-(((1-(isobutyryloxy)ethoxy)carbonyl)amino)ethyl)phosphoryl) methyl)propanoyl)-l-alanine

PHARMALEADS0 citations39
US10399936B2Sep 3, 2019

Industrial process for the preparation of (5S, 10S)-10-benzyl-16-methyl-11, 14, 18-trioxo-15, 17, 19-trioxa-2,7,8-trithia-12-azahenicosan-5-aminium(E)-3-carboxyacrylate salt

PHARMALEADS0 citations32
US10688113B2Jun 23, 2020

Methods of treating eye pain with aminophosphinic derivatives

PHARMALEADS0 citations30